Tumor Immunotherapy and Microenvironment

Stiftelsen Cancera

1/01/23 → 31/12/26

Project: Research

INCITE: Investigating the role of CMTM proteins in the regulation of PD-L1 expression

1/04/22 → 30/08/24

Project: Research

C2I: CHECKPOINT INHIBITORS IMPROVEMENT FOR THE TREATMENT OF CANCER

1/04/22 → 31/10/25

Project: Research

TRICK-ALDH: Assessment the impact of selective ALDH1 inhibitors on tumor infiltrating lymphocytes and the therapeutic benefit of Immune checkpoint blockers

Berchem, G. & Janji, B.

1/01/22 → 31/07/25

Project: Research

IMPACT 21: IMPROVING CANCER IMMUNOTHERAPY BY TARGETING HYPOXIA

Janji, B. & Benoit, A.

1/11/21 → 29/03/24

Project: Research

SMART COMBO: Improving cancer immunotherapy based on anti-PD-1 and STING agonists by combining small innovative molecule

Janji, B. & De Milito, A.

15/07/21 → 14/07/23

Project: Research

EMT-TNBC: EMT-dependent regulation of the ectonucleotidase CD73 in Triple Negative Breast Cancer and its role as a new therapeutic target

15/02/21 → 14/02/23

Project: Research

ACTIPHAGY: Actin remodeling in autophagy-mediated tumor immune escape,mechanistic aspects

Thomas, C., Janji, B. & Biolato, A. M.

1/12/19 → 30/04/24

Project: Research

NEUROIMMUNOTHERAPY PHASE II: Combining JQI and PD-1 as an innovative approach for the treatment of Childhood Neuroblastoma.

Fondatioun Kriibskrank Kanner

1/07/19 → 30/06/23

Project: Research

COMBATIC 2018: Improving T-cell and Macrophage Immune checkpoint blockades by combining autophagy inhibitors

1/01/19 → 31/07/23

Project: Research

Not started

PreCyse: Predictive biomarker profile for tumour and patient stratification for CyPep-1 guided ICI-therapy

FNRS - Fonds National de la Recherche Scientifique, Lions Clubs International

Project: Research

Finished

ACKR2 (CHEMOKINE RECEPTORS AND IMMUNOTHERAPY): Targeting chemokine receptors: An innovative strategy to reprogram cold to hot tumor microenvironment and to improve PD-1-based cancer immunotherapy

Janji, B. & Chevigne, A.

1/03/20 → 28/02/22

Project: Research

AUTOKIR: Combining selective pharmacological inhibitors of autophagy with NK immune checkpoint blockade anti-KIR: An innovative approach to improve NK-based cancer immunotherapy

Lions Clubs International

1/03/19 → 28/02/21

Project: Research

Anti-PD-1 and anti-CD47 combination: CD47 and PD-1 blockade: a new cutting edge COMBI approach to simultaneously stimulate macrophages and re-activate T cell-mediated destruction of highly aggressive metastatic breast tumors

15/02/19 → 30/04/21

Project: Research

Hypoxia 2017: Impact of the modulation of the intratumoral hypoxia on the improvement ofPD-1/PD-L1-based immune checkpoint blockade

Janji, B., Gallez, B., Berchem, G. & Haan, S.

1/10/17 → 30/09/20

Project: Research

CANBIO (Ernesto Gargiulo): Exosome proteins and RNA as biomarkers of prostate cancer progression and metastasis

Janji, B. & Gargiulo, E.

1/10/17 → 30/09/21

Project: Research

CANBIO (Malina Xiao): Role of hypoxia in the establishment of an immune suppressive tumour microenvironment

Janji, B. & Xiao, M.

15/09/17 → 14/09/21

Project: Research

Auto-Immune FC-II: Effect of PD-L1 blockade along with autophagy inhibition on the anti-tumor immune response

Fondation Cancer

1/05/16 → 30/04/19

Project: Research

Action des HDACis-IMiDs dans le MM: Impact of the immunomodulatory effect of the combination HDACis/IMiDs in myelome multiple (MM).

Janji, B., Berchem, G., Aouali, N. & Giuliani, M.

15/01/16 → 14/01/18

Project: Research

PD-1/PD-L1 NK: Effect of PD-1/PD-L1 immune checkpoint blockade on NK cell-mediated anti-tumor immune response