Projects per year
Hypoxic stress in the tumor microenvironment is associated with tumor resistance to anti-cancer therapies. Hypoxia has been reported to play a key role in shielding cells from immune cell attack either by promoting immune suppression, or by inducing many other oncogenic events and/or resistance mechanism (e.g. autophagy) in cancer cells, allowing to escape from immune cell attack. We are interested in studying the molecular mechanism by which hypoxia allows cancer cells escape from immune surveillance and to investigate how targeting autophagy could improve cancer immunotherapy by switching the tumor microenvironment from immunosuppressive to for cytotoxic immune cells. Our collaboration with Gustave Cancer Center (France) allows us to conduct research at the interface between fundamental and clinically-oriented research programs.
Dive into details
Select a country/territory to view shared publications and projects
Janji, B. & Benoit, A.
1/11/21 → 29/03/24
de Campos, N. S. P., Souza, B. S., da Silva, G. C. P., Porto, V. A., Chalbatani, G. M., Lagreca, G., Janji, B. & Suarez, E. R., 9 Mar 2022, In: Cancers. 14, 6, 1392.
Research output: Contribution to journal › Review article › peer-reviewOpen Access1 Citation (Scopus)
Xiao, M., Duhem, C., Chammout, A., Berchem, G. & Janji, B., Jun 2022, In: Journal of Cellular Biochemistry. 123, 6, p. 1025-1031 7 p.
Research output: Contribution to journal › Article › Research › peer-reviewOpen Access1 Citation (Scopus)
Hasmim, M., Janji, B., Tittarelli, A., Boutet, M., Baud, V., Viry, E., Billot, K., Nanbakhsh, A., Safta, T. B., Richon, C., Ferlicot, S., Donnadieu, E., Couve, S., Gardie, B., Orlanducci, F., Albiges, L., Thiery, J., Olive, D., & 2 others, 15 Apr 2022, In: Cancer Research. 82, 8, p. 1671 1 p.
Research output: Contribution to journal › EditorialOpen Access