Projects per year
Organisation profile
Organisation profile
The Transversal Translational Medicine (TTM) initiative of the Luxembourg Institute of Health aims to enhance the ability of biomedical stakeholder institutions to work translationally, fostering national and international bed-to-bench-to-bed collaborations and thereby acting as a bridge between fundamental research and clinical practice.
TTM aims to foster bed-to-bench-to-bed collaborations within LIH, inter-institutionally across Luxembourg and internationally, in view of implementing translational programmes across research topics, supported by specific platforms and infrastructures bridging between fundamental research and real-world healthcare. With the longstanding experience of the Luxembourgish National Centre for Excellence in Research (Parkinson’s disease) (NCER-PD) programme serving as a blueprint for translational bed-to-bench-to-bed cycles, TTM is perfectly positioned to enhance and develop translational initiatives in biomedical research and beyond.
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Collaborations and top research areas from the last five years
Profiles
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ParkinsonNet: ParkinsonNet – Réseau de compétence maladies neurodégéneratives
Krüger, R. (PI)
15/06/25 → 14/06/27
Project: Research
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LS-TTM: Precision Medicine in the field of neurodegeneration: 10 years of NCER-PD
Krüger, R. (PI)
1/04/25 → 31/12/25
Project: Research
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AIPD: Artificial Intelligence in Parkinson’s disease research
Krüger, R. (PI), Klucken, J. (PI), Ademola, E. (PhD Student) & Leonard, M. (PhD Student)
1/11/24 → 31/10/28
Project: Research
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Correction to: Propagative α-synuclein seeds as serum biomarkers for synucleinopathies (Nature Medicine, (2023), 29, 6, (1448-1455), 10.1038/s41591-023-02358-9)
Okuzumi, A., Hatano, T., Matsumoto, G., Nojiri, S., Ueno, S. I., Imamichi-Tatano, Y., Kimura, H., Kakuta, S., Kondo, A., Fukuhara, T., Li, Y., Funayama, M., Saiki, S., Taniguchi, D., Tsunemi, T., McIntyre, D., Gérardy, J. J., Mittelbronn, M., Kruger, R. & Uchiyama, Y. & 2 others, , Feb 2025, In: Nature Medicine. 31, 2, p. 698 1 p.Research output: Contribution to journal › Comment/debate
Open Access1 Citation (Scopus) -
Erratum: Author Correction: Mitochondria interaction networks show altered topological patterns in Parkinson's disease (NPJ systems biology and applications (2020) 6 1 DOI: 10.1038/s41540-020-00156-4.)
Zanin, M., Santos, B. F. R., Antony, P. M. A., Berenguer-Escuder, C., Larsen, S. B., Hanss, Z., Barbuti, P. A., Baumuratov, A. S., Grossmann, D., Capelle, C. M., Weber, J., Balling, R., Ollert, M., Krüger, R., Diederich, N. J. & HeFeng, F. Q., 3 Jul 2025, In: npj Systems Biology and Applications. 11, 1, p. 71 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Human induced pluripotent stem cell-derived dopaminergic neurons release alpha-synuclein through neuronal activity
Nuermaimaiti, M., Ishikawa, K. I., Oyama, G., Nonaka, R., Shiga, T., Jo, T., Tsunemi, T., Nakamura, R., Krüger, R., Akamatsu, W. & Hattori, N., Mar 2025, In: Neuroscience Research. 212, p. 105-114 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)