Translational Radiomics

Search results

  • 2024

    Corrigendum to ‘Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model’ [Ultrasound in Med & Biol. 49 (2023) 1082-1090, (S0301562922006664), (10.1016/j.ultrasmedbio.2022.12.006)]

    Zhang, Y., Wang, J., Ghobadi, S. N., Zhou, H., Huang, A., Gerosa, M., Hou, Q., Keunen, O., Golebiewska, A., Habte, F. G., Grant, G. A., Paulmurugan, R., Lee, K. S. & Wintermark, M., Mar 2024, In: Ultrasound in Medicine and Biology. 50, 3, p. 455 1 p.

    Research output: Contribution to journal › Comment/debate

    Open Access

  • Early-life influenza A (H1N1) infection independently programs brain connectivity, HPA AXIS and tissue-specific gene expression profiles

    Merz, M. P., Seal, S. V., Grova, N., Mériaux, S., Guebels, P., Kanli, G., Mommaerts, E., Nicot, N., Kaoma, T., Keunen, O., Nazarov, P. V. & Turner, J. D., 11 Mar 2024, In: Scientific Reports. 14, 1, 5898.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access

  • Predicting Hypoxia in Brain Tumors from Multiparametric MRI

    Perlo, D. (Main Author), Kanli, G., Boudissa, S. & Keunen, O., 25 Jan 2024, 7 p.

    Research output: Working paper › Preprint

  • 2023

    Author Correction: Federated learning enables big data for rare cancer boundary detection (Nature Communications, (2022), 13, 1, (7346), 10.1038/s41467-022-33407-5)

    Pati, S., Baid, U., Edwards, B., Sheller, M., Wang, S. H., Reina, G. A., Foley, P., Gruzdev, A., Karkada, D., Davatzikos, C., Sako, C., Ghodasara, S., Bilello, M., Mohan, S., Vollmuth, P., Brugnara, G., Preetha, C. J., Sahm, F., Maier-Hein, K. & Zenk, M. & 259 others, Bendszus, M., Wick, W., Calabrese, E., Rudie, J., Villanueva-Meyer, J., Cha, S., Ingalhalikar, M., Jadhav, M., Pandey, U., Saini, J., Garrett, J., Larson, M., Jeraj, R., Currie, S., Frood, R., Fatania, K., Huang, R. Y., Chang, K., Balaña, C., Capellades, J., Puig, J., Trenkler, J., Pichler, J., Necker, G., Haunschmidt, A., Meckel, S., Shukla, G., Liem, S., Alexander, G. S., Lombardo, J., Palmer, J. D., Flanders, A. E., Dicker, A. P., Sair, H. I., Jones, C. K., Venkataraman, A., Jiang, M., So, T. Y., Chen, C., Heng, P. A., Dou, Q., Kozubek, M., Lux, F., Michálek, J., Matula, P., Keřkovský, M., Kopřivová, T., Dostál, M., Vybíhal, V., Vogelbaum, M. A., Mitchell, J. R., Farinhas, J., Maldjian, J. A., Yogananda, C. G. B., Pinho, M. C., Reddy, D., Holcomb, J., Wagner, B. C., Ellingson, B. M., Cloughesy, T. F., Raymond, C., Oughourlian, T., Hagiwara, A., Wang, C., To, M. S., Bhardwaj, S., Chong, C., Agzarian, M., Falcão, A. X., Martins, S. B., Teixeira, B. C. A., Sprenger, F., Menotti, D., Lucio, D. R., LaMontagne, P., Marcus, D., Wiestler, B., Kofler, F., Ezhov, I., Metz, M., Jain, R., Lee, M., Lui, Y. W., McKinley, R., Slotboom, J., Radojewski, P., Meier, R., Wiest, R., Murcia, D., Fu, E., Haas, R., Thompson, J., Ormond, D. R., Badve, C., Sloan, A. E., Vadmal, V., Waite, K., Colen, R. R., Pei, L., Ak, M., Srinivasan, A., Bapuraj, J. R., Rao, A., Wang, N., Yoshiaki, O., Moritani, T., Turk, S., Lee, J., Prabhudesai, S., Morón, F., Mandel, J., Kamnitsas, K., Glocker, B., Dixon, L. V. M., Williams, M., Zampakis, P., Panagiotopoulos, V., Tsiganos, P., Alexiou, S., Haliassos, I., Zacharaki, E. I., Moustakas, K., Kalogeropoulou, C., Kardamakis, D. M., Choi, Y. S., Lee, S. K., Chang, J. H., Ahn, S. S., Luo, B., Poisson, L., Wen, N., Tiwari, P., Verma, R., Bareja, R., Yadav, I., Chen, J., Kumar, N., Smits, M., van der Voort, S. R., Alafandi, A., Incekara, F., Wijnenga, M. M. J., Kapsas, G., Gahrmann, R., Schouten, J. W., Dubbink, H. J., Vincent, A. J. P. E., van den Bent, M. J., French, P. J., Klein, S., Yuan, Y., Sharma, S., Tseng, T. C., Adabi, S., Niclou, S. P., Keunen, O., Hau, A. C., Vallières, M., Fortin, D., Lepage, M., Landman, B., Ramadass, K., Xu, K., Chotai, S., Chambless, L. B., Mistry, A., Thompson, R. C., Gusev, Y., Bhuvaneshwar, K., Sayah, A., Bencheqroun, C., Belouali, A., Madhavan, S., Booth, T. C., Chelliah, A., Modat, M., Shuaib, H., Dragos, C., Abayazeed, A., Kolodziej, K., Hill, M., Abbassy, A., Gamal, S., Mekhaimar, M., Qayati, M., Reyes, M., Park, J. E., Yun, J., Kim, H. S., Mahajan, A., Muzi, M., Benson, S., Beets-Tan, R. G. H., Teuwen, J., Herrera-Trujillo, A., Trujillo, M., Escobar, W., Abello, A., Bernal, J., Gómez, J., Choi, J., Baek, S., Kim, Y., Ismael, H., Allen, B., Buatti, J. M., Kotrotsou, A., Li, H., Weiss, T., Weller, M., Bink, A., Pouymayou, B., Shaykh, H. F., Saltz, J., Prasanna, P., Shrestha, S., Mani, K. M., Payne, D., Kurc, T., Pelaez, E., Franco-Maldonado, H., Loayza, F., Quevedo, S., Guevara, P., Torche, E., Mendoza, C., Vera, F., Ríos, E., López, E., Velastin, S. A., Ogbole, G., Soneye, M., Oyekunle, D., Odafe-Oyibotha, O., Osobu, B., Shu’aibu, M., Dorcas, A., Dako, F., Simpson, A. L., Hamghalam, M., Peoples, J. J., Hu, R., Tran, A., Cutler, D., Moraes, F. Y., Boss, M. A., Gimpel, J., Veettil, D. K., Schmidt, K., Bialecki, B., Marella, S., Price, C., Cimino, L., Apgar, C., Shah, P., Menze, B., Barnholtz-Sloan, J. S., Martin, J. & Bakas, S., 26 Jan 2023, In: Nature Communications. 14, 1, p. 436 436.

    Research output: Contribution to journal › Comment/debate

    Open Access
    3 Citations (Scopus)

  • Immune cell identity behind the Ktrans mapping of mouse glioblastoma

    Zhang, Y., Keunen, O., Golebiewska, A., Gerosa, M., Wang, J., Ghobadi, S. N., Huang, A., Hou, Q., Habte, F. G., Li, N., Grant, G., Paulmurugan, R., Lee, K. S. & Wintermark, M., Nov 2023, In: Magnetic Resonance Imaging. 103, p. 92-101 10 p.

    Research output: Contribution to journal › Article › Research › peer-review

  • Large-Scale Deep Learning Medical Image Methodology and Applications using Multiple GPUs

    Krishnasamy, E., Boudissa, S., Kanli, G., Marzal-Abarca, F. X., Keunen, O. & Bouvry, P., 12 Oct 2023, p. 17-22. 6 p.

    Research output: Contribution to conference › Paper › peer-review

  • Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model

    Zhang, Y., Wang, J., Ghobadi, S. N., Zhou, H., Huang, A., Gerosa, M., Hou, Q., Keunen, O., Golebiewska, A., Habte, F. G., Grant, G. A., Paulmurugan, R., Lee, K. S. & Wintermark, M., May 2023, In: Ultrasound in Medicine and Biology. 49, 5, p. 1082-1090 9 p.

    Research output: Contribution to journal › Article › Research › peer-review

    11 Citations (Scopus)
  • 2022

    Deciphering Human Glioblastoma Invasion Using a Developmental Mature Rat Brain Organoid Model

    Zhou, W., Thorsen, F. A., Grützmann, K., Mihaljevic, B., van Loon, B., Hossain, J. A., Golebiewska, A., Niclou, S., Bjørås, M., Tardito, S., Joesph, J. V., Martinez-Garcia, E., Lunavat, T. R., Saed, H. S., Bahador, M., Han, M., Fabian, C., Miletic, H., Li, X. & Wang, J. & 11 others, Dittmar, G., Keunen, O., Sarnow, K., Klink, B., Bjerkvig, R., Kanli, G., Nazarov, P., Schwab, S. G., Meiser, J., Jäger, C. & Mieczkowski, J., 15 Nov 2022, (DEVELOPMENTAL-CELL-D-22-00801).

    Research output: Working paper › Preprint

  • Exploiting Liver CT scans in Colorectal Carcinoma genomics mutation classification

    Perlo, D., Berton, L., Delpiano, A., Menchini, F., Tibaldi, S., Grosso, M. & Fonio, P., 2022, Proceedings - 2022 IEEE International Conference on Big Data, Big Data 2022. Tsumoto, S., Ohsawa, Y., Chen, L., Van den Poel, D., Hu, X., Motomura, Y., Takagi, T., Wu, L., Xie, Y., Abe, A. & Raghavan, V. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 4425-4433 9 p. (Proceedings - 2022 IEEE International Conference on Big Data, Big Data 2022).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

  • Federated learning enables big data for rare cancer boundary detection

    Pati, S., Baid, U., Edwards, B., Sheller, M., Wang, S. H., Reina, G. A., Foley, P., Gruzdev, A., Karkada, D., Davatzikos, C., Sako, C., Ghodasara, S., Bilello, M., Mohan, S., Vollmuth, P., Brugnara, G., Preetha, C. J., Sahm, F., Maier-Hein, K. & Zenk, M. & 259 others, Bendszus, M., Wick, W., Calabrese, E., Rudie, J., Villanueva-Meyer, J., Cha, S., Ingalhalikar, M., Jadhav, M., Pandey, U., Saini, J., Garrett, J., Larson, M., Jeraj, R., Currie, S., Frood, R., Fatania, K., Huang, R. Y., Chang, K., Quintero, C. B., Capellades, J., Puig, J., Trenkler, J., Pichler, J., Necker, G., Haunschmidt, A., Meckel, S., Shukla, G., Liem, S., Alexander, G. S., Lombardo, J., Palmer, J. D., Flanders, A. E., Dicker, A. P., Sair, H. I., Jones, C. K., Venkataraman, A., Jiang, M., So, T. Y., Chen, C., Heng, P. A., Dou, Q., Kozubek, M., Lux, F., Michálek, J., Matula, P., Keřkovský, M., Kopřivová, T., Dostál, M., Vybíhal, V., Vogelbaum, M. A., Mitchell, J. R., Farinhas, J., Maldjian, J. A., Yogananda, C. G. B., Pinho, M. C., Reddy, D., Holcomb, J., Wagner, B. C., Ellingson, B. M., Cloughesy, T. F., Raymond, C., Oughourlian, T., Hagiwara, A., Wang, C., To, M. S., Bhardwaj, S., Chong, C., Agzarian, M., Falcão, A. X., Martins, S. B., Teixeira, B. C. A., Sprenger, F., Menotti, D., Lucio, D. R., LaMontagne, P., Marcus, D., Wiestler, B., Kofler, F., Ezhov, I., Metz, M., Jain, R., Lee, M., Lui, Y. W., McKinley, R., Slotboom, J., Radojewski, P., Meier, R., Wiest, R., Murcia, D., Fu, E., Haas, R., Thompson, J., Ormond, D. R., Badve, C., Sloan, A. E., Vadmal, V., Waite, K., Colen, R. R., Pei, L., Ak, M., Srinivasan, A., Bapuraj, J. R., Rao, A., Wang, N., Yoshiaki, O., Moritani, T., Turk, S., Lee, J., Prabhudesai, S., Morón, F., Mandel, J., Kamnitsas, K., Glocker, B., Dixon, L. V. M., Williams, M., Zampakis, P., Panagiotopoulos, V., Tsiganos, P., Alexiou, S., Haliassos, I., Zacharaki, E. I., Moustakas, K., Kalogeropoulou, C., Kardamakis, D. M., Choi, Y. S., Lee, S. K., Chang, J. H., Ahn, S. S., Luo, B., Poisson, L., Wen, N., Tiwari, P., Verma, R., Bareja, R., Yadav, I., Chen, J., Kumar, N., Smits, M., van der Voort, S. R., Alafandi, A., Incekara, F., Wijnenga, M. M. J., Kapsas, G., Gahrmann, R., Schouten, J. W., Dubbink, H. J., Vincent, A. J. P. E., van den Bent, M. J., French, P. J., Klein, S., Yuan, Y., Sharma, S., Tseng, T. C., Adabi, S., Niclou, S. P., Keunen, O., Hau, A. C., Vallières, M., Fortin, D., Lepage, M., Landman, B., Ramadass, K., Xu, K., Chotai, S., Chambless, L. B., Mistry, A., Thompson, R. C., Gusev, Y., Bhuvaneshwar, K., Sayah, A., Bencheqroun, C., Belouali, A., Madhavan, S., Booth, T. C., Chelliah, A., Modat, M., Shuaib, H., Dragos, C., Abayazeed, A., Kolodziej, K., Hill, M., Abbassy, A., Gamal, S., Mekhaimar, M., Qayati, M., Reyes, M., Park, J. E., Yun, J., Kim, H. S., Mahajan, A., Muzi, M., Benson, S., Beets-Tan, R. G. H., Teuwen, J., Herrera-Trujillo, A., Trujillo, M., Escobar, W., Abello, A., Bernal, J., Gómez, J., Choi, J., Baek, S., Kim, Y., Ismael, H., Allen, B., Buatti, J. M., Kotrotsou, A., Li, H., Weiss, T., Weller, M., Bink, A., Pouymayou, B., Shaykh, H. F., Saltz, J., Prasanna, P., Shrestha, S., Mani, K. M., Payne, D., Kurc, T., Pelaez, E., Franco-Maldonado, H., Loayza, F., Quevedo, S., Guevara, P., Torche, E., Mendoza, C., Vera, F., Ríos, E., López, E., Velastin, S. A., Ogbole, G., Soneye, M., Oyekunle, D., Odafe-Oyibotha, O., Osobu, B., Shu’aibu, M., Dorcas, A., Dako, F., Simpson, A. L., Hamghalam, M., Peoples, J. J., Hu, R., Tran, A., Cutler, D., Moraes, F. Y., Boss, M. A., Gimpel, J., Veettil, D. K., Schmidt, K., Bialecki, B., Marella, S., Price, C., Cimino, L., Apgar, C., Shah, P., Menze, B., Barnholtz-Sloan, J. S., Martin, J. & Bakas, S., 5 Dec 2022, In: Nature Communications. 13, 1, 7346.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    102 Citations (Scopus)

  • Federated Learning Enables Big Data for Rare Cancer Boundary Detection

    Pati, S., Baid, U., Edwards, B., Sheller, M., Wang, S.-H., Reina, G. A., Foley, P., Gruzdev, A., Karkada, D., Davatzikos, C., Sako, C., Ghodasara, S., Bilello, M., Mohan, S., Vollmuth, P., Brugnara, G., Preetha, C. J., Sahm, F., Maier-Hein, K. & Zenk, M. & 259 others, Bendszus, M., Wick, W., Calabrese, E., Rudie, J., Villanueva-Meyer, J., Cha, S., Ingalhalikar, M., Jadhav, M., Pandey, U., Saini, J., Garrett, J., Larson, M., Jeraj, R., Currie, S., Frood, R., Fatania, K., Huang, R. Y., Chang, K., Balana, C., Capellades, J., Puig, J., Trenkler, J., Pichler, J., Necker, G., Haunschmidt, A., Meckel, S., Shukla, G., Liem, S., Alexander, G. S., Lombardo, J., Palmer, J. D., Flanders, A. E., Dicker, A. P., Sair, H. I., Jones, C. K., Venkataraman, A., Jiang, M., So, T. Y., Chen, C., Heng, P. A., Dou, Q., Kozubek, M., Lux, F., Michálek, J., Matula, P., Keřkovský, M., Kopřivová, T., Dostál, M., Vybíhal, V., Vogelbaum, M. A., Mitchell, J. R., Farinhas, J., Maldjian, J. A., Yogananda, C. G. B., Pinho, M. C., Reddy, D., Holcomb, J., Wagner, B. C., Ellingson, B. M., Cloughesy, T. F., Raymond, C., Oughourlian, T., Hagiwara, A., Wang, C., To, M.-S., Bhardwaj, S., Chong, C., Agzarian, M., Falcão, A. X., Martins, S. B., Teixeira, B. C. A., Sprenger, F., Menotti, D., Lucio, D. R., LaMontagne, P., Marcus, D., Wiestler, B., Kofler, F., Ezhov, I., Metz, M., Jain, R., Lee, M., Lui, Y. W., McKinley, R., Slotboom, J., Radojewski, P., Meier, R., Wiest, R., Murcia, D., Fu, E., Haas, R., Thompson, J., Ormond, D. R., Badve, C., Sloan, A. E., Vadmal, V., Waite, K., Colen, R. R., Pei, L., Ak, M., Srinivasan, A., Bapuraj, J. R., Rao, A., Wang, N., Yoshiaki, O., Moritani, T., Turk, S., Lee, J., Prabhudesai, S., Morón, F., Mandel, J., Kamnitsas, K., Glocker, B., Dixon, L. V. M., Williams, M., Zampakis, P., Panagiotopoulos, V., Tsiganos, P., Alexiou, S., Haliassos, I., Zacharaki, E. I., Moustakas, K., Kalogeropoulou, C., Kardamakis, D. M., Choi, Y. S., Lee, S.-K., Chang, J. H., Ahn, S. S., Luo, B., Poisson, L., Wen, N., Tiwari, P., Verma, R., Bareja, R., Yadav, I., Chen, J., Kumar, N., Smits, M., Voort, S. R. V. D., Alafandi, A., Incekara, F., Wijnenga, M. M., Kapsas, G., Gahrmann, R., Schouten, J. W., Dubbink, H. J., Vincent, A. J., Bent, M. J. V. D., French, P. J., Klein, S., Yuan, Y., Sharma, S., Tseng, T.-C., Adabi, S., Niclou, S. P., Keunen, O., Hau, A.-C., Vallières, M., Fortin, D., Lepage, M., Landman, B., Ramadass, K., Xu, K., Chotai, S., Chambless, L. B., Mistry, A., Thompson, R. C., Gusev, Y., Bhuvaneshwar, K., Sayah, A., Bencheqroun, C., Belouali, A., Madhavan, S., Booth, T. C., Chelliah, A., Modat, M., Shuaib, H., Dragos, C., Abayazeed, A., Kolodziej, K., Hill, M., Abbassy, A., Gamal, S., Mekhaimar, M., Qayati, M., Reyes, M., Park, J. E., Yun, J., Kim, H. S., Mahajan, A., Muzi, M., Benson, S., Beets-Tan, R. G. H., Teuwen, J., Herrera-Trujillo, A., Trujillo, M., Escobar, W., Abello, A., Bernal, J., Gómez, J., Choi, J., Baek, S., Kim, Y., Ismael, H., Allen, B., Buatti, J. M., Kotrotsou, A., Li, H., Weiss, T., Weller, M., Bink, A., Pouymayou, B., Shaykh, H. F., Saltz, J., Prasanna, P., Shrestha, S., Mani, K. M., Payne, D., Kurc, T., Pelaez, E., Franco-Maldonado, H., Loayza, F., Quevedo, S., Guevara, P., Torche, E., Mendoza, C., Vera, F., Ríos, E., López, E., Velastin, S. A., Ogbole, G., Oyekunle, D., Odafe-Oyibotha, O., Osobu, B., Shu'aibu, M., Dorcas, A., Soneye, M., Dako, F., Simpson, A. L., Hamghalam, M., Peoples, J. J., Hu, R., Tran, A., Cutler, D., Moraes, F. Y., Boss, M. A., Gimpel, J., Veettil, D. K., Schmidt, K., Bialecki, B., Marella, S., Price, C., Cimino, L., Apgar, C., Shah, P., Menze, B., Barnholtz-Sloan, J. S., Martin, J. & Bakas, S., 22 Apr 2022.

    Research output: Working paper › Preprint

    File
    64 Downloads (Pure)

  • Molecular Identity Changes of Tumor-Associated Macrophages and Microglia after MRgFUS induced BBB Opening in a Mouse Glioblastoma Model

    Zhang, Y., Wang, J., Ghobadi, S., Zhou, H., Huang, A., Gerosa, M., Hou, Q., Keunen, O., Golebiewska, A., Habte, F., Grant, G., Paulmurugan, R., Lee, K. & Wintermark, M., 15 Mar 2022, Research Square.

    Research output: Working paper › Preprint

    Open Access

  • The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model

    Sauvage, D., Bosseler, M., Viry, E., Kanli, G., Oudin, A., Berchem, G., Keunen, O. & Janji, B., 6 Sept 2022, In: Cells. 11, 18, 2783.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    6 Citations (Scopus)
  • 2021

    Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis

    Aasen, S. N., Espedal, H., Keunen, O., Adamsen, T. C. H., Bjerkvig, R. & Thorsen, F., 14 Oct 2021, In: Neuro-Oncology Advances. 3, 1, vdab151.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    3 Citations (Scopus)

  • Inhibition of GBM invasion by the A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid (AMPA) Glutamate receptor antagonist Perampanel

    Sarnow, K., Kanli, G., Keunen, O. & Bjerkvig, R., 9 Sept 2021, In: Neuro-Oncology. 23, Suppl.2, p. 10-10 OS06.6A.

    Research output: Contribution to journal › Meeting Abstract › peer-review

    Open Access

  • Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy

    Zhang, Y., Buckmaster, P. S., Qiu, L., Wang, J., Keunen, O., Ghobadi, S. N., Huang, A., Hou, Q., Li, N., Narang, S., Habte, F. G., Bertram, E. H., Lee, K. S. & Wintermark, M., Sept 2021, In: Experimental Neurology. 343, p. 113761 113761.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    6 Citations (Scopus)

  • Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors

    Oudin, A., Baus, V., Barthelemy, V., Fabian, C., Klein, E., Dieterle, M., Wantz, M., Hau, A. C., Dording, C., Bernard, A., Michelucci, A., Yabo, Y. A., Kanli, G., Keunen, O., Bjerkvig, R., Niclou, S. P. & Golebiewska, A., 18 Jun 2021, In: STAR Protocols. 2, 2, p. 100534 100534.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    13 Citations (Scopus)

  • Relationship between Metabolically Unhealthy Obesity and Visceral Adipose Tissue in Youth

    Samouda, H., Leite, S., Gilson, G., Van Nieuwenhuyse, J. P., Keunen, O. & Beaufort, C. D., 1 Dec 2021, In: Obesity. 29, p. 155-155 1 p., Poster 270.

    Research output: Contribution to journal › Meeting Abstract › peer-review

    Open Access
  • 2020

    Is there a prominent role for MR spectroscopy in the clinical management of brain tumors?

    Keunen, O. & Simone, P. N., 1 Jul 2020, In: Neuro-Oncology. 22, 7, p. 903-904 2 p.

    Research output: Contribution to journal › Editorial

    Open Access
    1 Citation (Scopus)

  • Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

    Golebiewska, A., Hau, A. C., Oudin, A., Stieber, D., Yabo, Y. A., Baus, V., Barthelemy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., Michelucci, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P. V., Azuaje, F., De Falco, A., Flies, B. & Richart, L. & 21 others, Poovathingal, S., Arns, T., Grzyb, K., Mock, A., Herold-Mende, C., Steino, A., Brown, D., May, P., Miletic, H., Malta, T. M., Noushmehr, H., Kwon, Y. J., Jahn, W., Klink, B., Tanner, G., Stead, L. F., Mittelbronn, M., Skupin, A., Hertel, F., Bjerkvig, R. & Niclou, S. P., Dec 2020, In: Acta Neuropathologica. 140, 6, p. 919-949 31 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    77 Citations (Scopus)
  • 2019

    Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood–brain barrier

    Aasen, S. N., Espedal, H., Holte, C. F., Keunen, O., Karlsen, T. V., Tenstad, O., Maherally, Z., Miletic, H., Hoang, T., Eikeland, A. V., Baghirov, H., Olberg, D. E., Pilkington, G. J., Sarkar, G., Jenkins, R. B., Sundstrøm, T., Bjerkvig, R. & Thorsen, F., Nov 2019, In: Molecular Cancer Therapeutics. 18, 11, p. 2171-2181 11 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    15 Citations (Scopus)

  • Iterative methods for fast reconstruction of undersampled dynamic contrast-enhanced MRI data

    Walner, H., Bartoš, M., Mangová, M., Keunen, O., Bjerkvig, R., Jiřík, R. & Šorel, M., 2019, In: IFMBE Proceedings. 68, 1, p. 267-271 5 p.

    Research output: Contribution to journal › Conference article › peer-review

  • Spatially regularized estimation of the tissue homogeneity model parameters in DCE-MRI using proximal minimization

    Bartoš, M., Rajmic, P., Šorel, M., Mangová, M., Keunen, O. & Jiřík, R., 1 Dec 2019, In: Magnetic Resonance in Medicine. 82, 6, p. 2257-2272 16 p.

    Research output: Contribution to journal › Article › Research › peer-review

    3 Citations (Scopus)

  • THER-11. Peptide mediated permeabilization of the blood-brain-barrier improves drug delivery to brain metastasis

    Aasen, S. N., Espedal, H., Holte, C. F., Keunen, O., Karlsen, T. V., Tenstad, O., Maherally, Z., Miletic, H., Hoang, T., Eikeland, A. V., Baghirov, H., Olberg, D. E., Pilkington, G. J., Sarkar, G., Jenkins, R. B., Sundstrøm, T., Bjerkvig, R. & Thorsen, F., Aug 2019, In: Neuro-Oncology Advances. 1, Suppl.1, p. i13

    Research output: Contribution to journal › Meeting Abstract › peer-review

    Open Access
  • 2018

    EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors

    Dudvarski Stanković, N., Bicker, F., Keller, S., Jones, D. T. W., Harter, P. N., Kienzle, A., Gillmann, C., Arnold, P., Golebiewska, A., Keunen, O., Giese, A., von Deimling, A., Bäuerle, T., Niclou, S. P., Mittelbronn, M., Ye, W., Pfister, S. M. & Schmidt, M. H. H., Sept 2018, In: EMBO Molecular Medicine. 10, 9, e8420.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    36 Citations (Scopus)

  • Improved treatment of melanoma brain metastasis using a synthetic peptide

    Aasen, S., Espedal, H., Holte, C. F., Keunen, O., Karlsen, T. V., Tenstad, O., Maherally, Z., Miletic, H., Eikeland, A. V., Baghirov, H., Bjerkvig, R., Olberg, D. E., Sarkar, G., Jenkins, R. & Thorsen, F., Nov 2018, In: Neuro-Oncology. 20, Suppl.6, p. 275-276 TMOD-34.

    Research output: Contribution to journal › Meeting Abstract › peer-review

    Open Access

  • Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma

    Obad, N., Espedal, H., Jirik, R., Sakariassen, P. O., Brekke Rygh, C., Lund-Johansen, M., Taxt, T., Niclou, S. P., Bjerkvig, R. & Keunen, O., 1 Oct 2018, In: Journal of Cerebral Blood Flow and Metabolism. 38, 10, p. 1741-1753 13 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    15 Citations (Scopus)

  • The good drug, the bad barrier and the handy peptide: Improved treatment of experimental melanoma brain metastases using a synthetic peptide

    Aasen, S. N., Espedal, H., Holte, C. F., Keunen, O., Karlsen, T. V., Tenstad, O., Baghirov, H., Olberg, D. E., Bjerkvig, R., Sarkar, G. & Thorsen, F., Jul 2018, In: Cancer Research. 78, 13 Suppl., LB-314.

    Research output: Contribution to journal › Meeting Abstract › peer-review

    Open Access
  • 2017

    Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways

    Fack, F., Tardito, S., Hochart, G., Oudin, A., Zheng, L., Fritah, S., Golebiewska, A., Nazarov, P. V., Bernard, A., Hau, A. C., Keunen, O., Leenders, W., Lund-Johansen, M., Stauber, J., Gottlieb, E., Bjerkvig, R. & Niclou, S. P., Dec 2017, In: EMBO Molecular Medicine. 9, 12, p. 1681-1695 15 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    101 Citations (Scopus)

  • Subtraction of subcutaneous fat to improve the prediction of visceral adiposity: exploring a new anthropometric track in overweight and obese youth

    Samouda, H., De Beaufort, C., Stranges, S., Van Nieuwenhuyse, J. P., Dooms, G., Keunen, O., Leite, S., Vaillant, M., Lair, M. L. & Dadoun, F., Aug 2017, In: Pediatric Diabetes. 18, 5, p. 399-404 6 p.

    Research output: Contribution to journal › Article › Research › peer-review

    5 Citations (Scopus)
  • 2016

    Cardiometabolic risk: Leg fat is protective during childhood

    Samouda, H., De Beaufort, C., Stranges, S., Hirsch, M., Van Nieuwenhuyse, J. P., Dooms, G., Gilson, G., Keunen, O., Leite, S., Vaillant, M., Lair, M. L. & Dadoun, F., 1 Jun 2016, In: Pediatric Diabetes. 17, 4, p. 300-308 9 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    17 Citations (Scopus)

  • EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation

    Eskilsson, E., Rosland, G. V., Talasila, K. M., Knappskog, S., Keunen, O., Sottoriva, A., Foerster, S., Solecki, G., Taxt, T., Jirik, R., Fritah, S., Harter, P. N., Välk, K., Al Hossain, J., Joseph, J. V., Jahedi, R., Saed, H. S., Piccirillo, S. G., Spiteri, I. & Euskirchen, P. & 10 others, Graziani, G., Daubon, T., Lund-Johansen, M., Enger, P. Ø., Winkler, F., Ritter, C. A., Niclou, S. P., Watts, C., Bjerkvig, R. & Miletic, H., Dec 2016, In: Neuro-Oncology. 18, 12, p. 1644-1655 12 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    80 Citations (Scopus)

  • Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

    Bougnaud, S., Golebiewska, A., Oudin, A., Keunen, O., Harter, P. N., Mäder, L., Azuaje, F., Fritah, S., Stieber, D., Kaoma, T., Vallar, L., Brons, N. H. C., Daubon, T., Miletic, H., Sundstrøm, T., Herold-Mende, C., Mittelbronn, M., Bjerkvig, R. & Niclou, S. P., 31 May 2016, In: Oncotarget. 7, 22, p. 31955-31971 17 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    61 Citations (Scopus)
  • 2015

    Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

    Fack, F., Espedal, H., Keunen, O., Golebiewska, A., Obad, N., Harter, P. N., Mittelbronn, M., Bähr, O., Weyerbrock, A., Stuhr, L., Miletic, H., Sakariassen, P., Stieber, D., Rygh, C. B., Lund-Johansen, M., Zheng, L., Gottlieb, E., Niclou, S. P. & Bjerkvig, R., 17 Jan 2015, In: Acta Neuropathologica. 129, 1, p. 115-131 17 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    115 Citations (Scopus)

  • Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

    Tardito, S., Oudin, A., Ahmed, S. U., Fack, F., Keunen, O., Zheng, L., Miletic, H., Sakariassen, P. Ø., Weinstock, A., Wagner, A., Lindsay, S. L., Hock, A. K., Barnett, S. C., Ruppin, E., Harald MØrkve, S., Lund-Johansen, M., Chalmers, A. J., Bjerkvig, R., Niclou, S. P. & Gottlieb, E., 27 Nov 2015, In: Nature Cell Biology. 17, 12, p. 1556-1568 13 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    406 Citations (Scopus)