Projects per year
Organisation profile
Organisation profile
The Translational Medicine Operations Hub (TMOH) ensures a full support to clinical research from the planning of the clinical research studies to their execution and closure via the collection, processing, storage and analysis of high-quality biological samples and structured clinical data.
The Translational Medicine Operations Hub (TMOH) includes the operational units of the LIH (CPMO, CIEC, CCMS, IBBL) and its collaborative platforms (LCTR, DMSP, LuxGen, RPP) to integrate and optimise their accessibility, workflows and project/portfolio oversight.
The TMOH facilitates intra-institutional research, as well as transversal translational projects of “Research Luxembourg” and collaborations with external partners. These include publicly funded Research Projects like LITMUS, NCER-PD and CLINNOVA, as well as collaborations with industry partners. The central entry point for new projects is the CPMO, which will guide researchers and their projects through the governance and approval process, as well as plan and track project execution.
The mission of TMOH is to improve patients’ lives by providing Operational Excellence:
- Single Point of contact regarding Research Services for internal & external stakeholders
- Seamless workflow and high-quality project execution
- Consultation for projects regarding project design, operations, regulatory aspects, among others
- Inbuilt collaboration (clear processes, interfaces, R&R) and exchange of resources (technologies, SME)
- Transparent information/communication E2E (TMOH, LIH and beyond...)
- Continuous development – of methods, technology, science, quality, and processes, among others
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Collaborations and top research areas from the last five years
Profiles
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NVDX3-CLN01: Safety and efficacy of Novadip 3D osteogenic implants
1/08/23 → 31/12/25
Project: Consultancy
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NVDX3-spine: Safety and efficacy of Novadip autologous 3D osteogenic implant in the treatment of recalcitrant limb nonunion
Gantenbein, M. & Alexandre, M.
1/07/23 → 30/06/25
Project: Consultancy
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Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus
Mgrditchian, T., Brown-Clay, J., Hoffmann, C., Müller, T., Filali, L., Ockfen, E., Mao, X., Moreau, F., Casellas, C. P., Kaoma, T., Mittelbronn, M. & Thomas, C., 15 May 2023, In: Frontiers in Cell and Developmental Biology. 11, 1100938.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Actin cytoskeleton remodeling at the cancer cell side of the immunological synapse: good, bad, or both?
Thomas, C., Ockfen, E., Filali, L., Fernandes, D. P. & Hoffmann, C., 21 Sept 2023, (Accepted/In press) In: Frontiers in Immunology. 14, 1 p., 1276602.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice
Parrish, A., Boudaud, M., Grant, E. T., Willieme, S., Neumann, M., Wolter, M., Craig, S. Z., De Sciscio, A., Cosma, A., Hunewald, O., Ollert, M. & Desai, M. S., 11 Sept 2023, (E-pub ahead of print) In: Nature Microbiology.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Datasets
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Optimized Multicolor Immunofluorescence Panel (OMIP) Database
Cosma, A. (Creator), Hedin, F. (Creator) & Masquelier, C. (Data Collector), salesforce, 2022
https://public.tableau.com/app/profile/fanny2212/viz/OMIP_ISAC/Menu
Dataset
Equipment
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Imaging Flow Cytometry
Antonio Cosma (Manager)
Platform National CytometryFacility/equipment: Equipment
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