Projects per year
Organisation profile
Organisation profile
The Translational and Clinical Immunology group aims to discover novel molecular and cellular intervention candidates and identify diagnostic and prognostic biomarkers for non-communicable complex diseases and infectious diseases, by integrating both pre-clinical animal models and human samples from cohorts and clinical trials. The overall research topics of the group are divided into the following specific themes:
1. Identify novel mechanisms leading to immune tolerance through allergen-specific immunotherapies used for treating various allergic diseases (led by Prof. Markus Ollert).
2. Investigate the potential links between acute viral infection, host immune dysregulations and the subsequent development of autoimmune, allergic and neurological disorders (led by Prof. Markus Ollert).
3. Identify the molecular mechanisms underlying the immune ageing process and their implementation in ageing-associated diseases (led by Dr. Feng Hefeng).
4. Develop and apply cutting-edge deep immunophenotyping strategies to enhance the understanding of immune dysregulations in various complex and infectious diseases (led by Dr. Feng Hefeng).
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Collaborations and top research areas from the last five years
Profiles
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CRIS-CD8TERA: CRISPR screening in primary human CD8 T cells identifies regulators modulating CD8 TEMRA differentiation
Hefeng, F. Q. (PI)
1/09/24 → 31/07/27
Project: Research
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IFAM: Exploring early immune mechanisms of food allergic reactions in humans to develop markers and treatment targets
Kuehn, A. (PI), Cosma, A. (Partner), Hilger, C. (Partner), Ollert, M. (Partner), Graf, T. (Partner) & Nagy, N. (Partner)
FNR - Fonds National de la Recherche
1/07/24 → 30/09/27
Project: Research
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Nextimmune-2 (Andrea Riviello): Regulation of the allergic airway Th2 response by redox metabolism
Ollert, M. (PI) & Riviello, A. (PhD Student)
FNR - Fonds National de la Recherche
15/01/24 → 14/01/28
Project: Research
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AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI-EANO position paper
Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., Backes, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., Michelucci, A., Nazarov, P. V., Niclou, S. P., Nocentini, G., Ollert, M. & Preusser, M. & 10 others, , Jun 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 6, p. 1419-1439 21 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Asthma and rhinitis control in adolescents and young adults: A real-world MASK-air study
Sousa-Pinto, B., Valiulis, A., Melén, E., Koppelman, G. H., Papadopoulos, N. G., Makela, M., Haahtela, T., Bonini, M., Braido, F., Brussino, L., Cruz, A. A., Fiocchi, A., Giovannini, M., Gemicioglu, B., Kulus, M., Kuna, P., Kupczyk, M., Kvedariene, V., Larenas-Linnemann, D. E. & Louis, R. & 19 others, , Feb 2024, In: Pediatric Allergy and Immunology. 35, 2, e14080.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)
Bousquet, J., Schünemann, H. J., Sousa-Pinto, B., Zuberbier, T., Togias, A., Samolinski, B., Bedbrook, A., Czarlewski, W., Hofmann-Apitius, M., Litynska, J., Vieira, R. J., Anto, J. M., Fonseca, J. A., Brozek, J., Bognanni, A., Brussino, L., Canonica, G. W., Cherrez-Ojeda, I., Cruz, A. A. & Vecillas, L. D. L. & 200 others, , Oct 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 10, p. 2648-2668.e2Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus)