Organisation profile

Organisation profile

The Translational and Clinical Immunology group aims to discover novel molecular and cellular intervention candidates and identify diagnostic and prognostic biomarkers for non-communicable complex diseases and infectious diseases, by integrating both pre-clinical animal models and human samples from cohorts and clinical trials. The overall research topics of the group are divided into the following specific themes:

1. Identify novel mechanisms leading to immune tolerance through allergen-specific immunotherapies used for treating various allergic diseases (led by Prof. Markus Ollert).

2. Investigate the potential links between acute viral infection, host immune dysregulations and the subsequent development of autoimmune, allergic and neurological disorders (led by Prof. Markus Ollert).

3. Identify the molecular mechanisms underlying the immune ageing process and their implementation in ageing-associated diseases (led by Dr. Feng Hefeng).

4. Develop and apply cutting-edge deep immunophenotyping strategies to enhance the understanding of immune dysregulations in various complex and infectious diseases (led by Dr. Feng Hefeng).

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Collaborations and top research areas from the last five years

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  • AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI-EANO position paper

    Turner, M. C., Radzikowska, U., Ferastraoaru, D. E., Pascal, M., Wesseling, P., McCraw, A., Backes, C., Bax, H. J., Bergmann, C., Bianchini, R., Cari, L., de las Vecillas, L., Izquierdo, E., Lind-Holm Mogensen, F., Michelucci, A., Nazarov, P. V., Niclou, S. P., Nocentini, G., Ollert, M. & Preusser, M. & 10 others, Rohr-Udilova, N., Scafidi, A., Toth, R., Van Hemelrijck, M., Weller, M., Jappe, U., Escribese, M. M., Jensen-Jarolim, E., Karagiannis, S. N. & Poli, A., Jun 2024, In: Allergy: European Journal of Allergy and Clinical Immunology. 79, 6, p. 1419-1439 21 p.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
  • Asthma and rhinitis control in adolescents and young adults: A real-world MASK-air study

    Sousa-Pinto, B., Valiulis, A., Melén, E., Koppelman, G. H., Papadopoulos, N. G., Makela, M., Haahtela, T., Bonini, M., Braido, F., Brussino, L., Cruz, A. A., Fiocchi, A., Giovannini, M., Gemicioglu, B., Kulus, M., Kuna, P., Kupczyk, M., Kvedariene, V., Larenas-Linnemann, D. E. & Louis, R. & 19 others, Morais-Almeida, M., Niedoszytko, M., Ollert, M., Pfaar, O., Regateiro, F. S., Roberts, G., Samolinski, B., Savouré, M., Taborda-Barata, L., Toppila-Salmi, S., Ventura, M. T., Vazquez-Ortiz, M., Vieira, R. J., Fonseca, J. A., Yorgancioglu, A., Zuberbier, T., Anto, J. M., Bousquet, J. & Pham-Thi, N., Feb 2024, In: Pediatric Allergy and Immunology. 35, 2, e14080.

    Research output: Contribution to journalArticleResearchpeer-review

    Open Access
    3 Citations (Scopus)
  • Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)

    Bousquet, J., Schünemann, H. J., Sousa-Pinto, B., Zuberbier, T., Togias, A., Samolinski, B., Bedbrook, A., Czarlewski, W., Hofmann-Apitius, M., Litynska, J., Vieira, R. J., Anto, J. M., Fonseca, J. A., Brozek, J., Bognanni, A., Brussino, L., Canonica, G. W., Cherrez-Ojeda, I., Cruz, A. A. & Vecillas, L. D. L. & 200 others, Dykewicz, M., Gemicioglu, B., Giovannini, M., Haahtela, T., Jacobs, M., Jacomelli, C., Klimek, L., Kvedariene, V., Larenas-Linnemann, D. E., Louis, G., Lourenço, O., Leemann, L., Morais-Almeida, M., Neves, A. L., Nadeau, K. C., Nowak, A., Palamarchuk, Y., Palkonen, S., Papadopoulos, N. G., Parmelli, E., Pereira, A. M., Pfaar, O., Regateiro, F. S., Savouré, M., Taborda-Barata, L., Toppila-Salmi, S. K., Torres, M. J., Valiulis, A., Ventura, M. T., Williams, S., Yepes-Nuñez, J. J., Yorgancioglu, A., Zhang, L., Zuberbier, J., Abdul Latiff, A. H., Abdullah, B., Agache, I., Al-Ahmad, M., Al-Nesf, M. A., Al Shaikh, N. A., Amaral, R., Ansotegui, I. J., Asllani, J., Balotro-Torres, M. C., Bergmann, K. C., Bernstein, J. A., Bindslev-Jensen, C., Blaiss, M. S., Bonaglia, C., Bonini, M., Bossé, I., Braido, F., Caballero-Fonseca, F., Camargos, P., Carreiro-Martins, P., Casale, T., Castillo-Vizuete, J. A., Cecchi, L., Teixeira, M. D. C., Chang, Y. S., Loureiro, C. C., Christoff, G., Ciprandi, G., Cirule, I., Correia-de-Sousa, J., Costa, E. M., Cvetkovski, B., de Vries, G., Del Giacco, S., Devillier, P., Dokic, D., Douagui, H., Durham, S. R., Enecilla, M. L., Fiocchi, A., Fokkens, W. J., Fontaine, J. F., Gawlik, R., Gereda, J. E., Gil-Mata, S., Giuliano, A. F. M., Gotua, M., Gradauskiene, B., Guzman, M. A., Hossny, E., Hrubiško, M., Iinuma, T., Irani, C., Ispayeva, Z., Ivancevich, J. C., Jartti, T., Jeseňák, M., Julge, K., Jutel, M., Kaidashev, I., Bennoor, K. S., Khaltaev, N., Kirenga, B., Kraxner, H., Kull, I., Kulus, M., Kuna, P., Kupczyk, M., Kurchenko, A., La Grutta, S., Lane, S., Miculinic, N., Lee, S. M., Le Thi Tuyet, L., Lkhagvaa, B., Louis, R., Mahboub, B., Makela, M., Makris, M., Maurer, M., Melén, E., Milenkovic, B., Mohammad, Y., Moniuszko, M., Montefort, S., Moreira, A., Moreno, P., Mullol, J., Nadif, R., Nakonechna, A., Navarro-Locsin, C. G., Neffen, H. E., Nekam, K., Niedoszytko, M., Nunes, E., Nyembue, D., O'Hehir, R., Ollert, M., Ohta, K., Okamoto, Y., Okubo, K., Olze, H., Padukudru, M. A., Palomares, O., Pali-Schöll, I., Panzner, P., Palosuo, K., Park, H. S., Passalacqua, G., Patella, V., Pawankar, R., Pétré, B., Pitsios, C., Plavec, D., Popov, T. A., Puggioni, F., Quirce, S., Raciborski, F., Ramonaité, A., Recto, M., Repka-Ramirez, S., Roberts, G., Robles-Velasco, K., Roche, N., Rodriguez-Gonzalez, M., Romualdez, J. A., Rottem, M., Rouadi, P. W., Salapatas, M., Sastre, J., Serpa, F. S., Sayah, Z., Scichilone, N., Senna, G., Sisul, J. C., Solé, D., Soto-Martinez, M. E., Sova, M., Sozinova, O., Stevanovic, K., Ulrik, C. S., Szylling, A., Tan, F. M., Tantilipikorn, P., Todo-Bom, A., Tomic-Spiric, V., Tsaryk, V., Tsiligianni, I., Urrutia-Pereira, M., Rostan, M. V., Sofiev, M., Valovirta, E., Van Eerd, M., Van Ganse, E., Vasankari, T., Vichyanond, P., Viegi, G., Wallace, D., Wang, D. Y., Waserman, S., Wong, G., Worm, M., Yusuf, O. M., Zaitoun, F. & Zidarn, M., Oct 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 10, p. 2648-2668.e2

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1 Citation (Scopus)