Translational & Clinical Immunology

Organisation profile

Organisation profile

The Translational and Clinical Immunology group aims to discover novel molecular and cellular intervention candidates and identify diagnostic and prognostic biomarkers for non-communicable complex diseases and infectious diseases, by integrating both pre-clinical animal models and human samples from cohorts and clinical trials. The overall research topics of the group are divided into the following specific themes:

1. Identify novel mechanisms leading to immune tolerance through allergen-specific immunotherapies used for treating various allergic diseases (led by Prof. Markus Ollert).

2. Investigate the potential links between acute viral infection, host immune dysregulations and the subsequent development of autoimmune, allergic and neurological disorders (led by Prof. Markus Ollert).

3. Identify the molecular mechanisms underlying the immune ageing process and their implementation in ageing-associated diseases (led by Dr. Feng Hefeng).

4. Develop and apply cutting-edge deep immunophenotyping strategies to enhance the understanding of immune dysregulations in various complex and infectious diseases (led by Dr. Feng Hefeng).

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  • Adherence to inhaled corticosteroids and long-acting β2-agonists in asthma: A MASK-air study

    Sousa-Pinto, B., Louis, R., Anto, J. M., Amaral, R., Sá-Sousa, A., Czarlewski, W., Brussino, L., Canonica, G. W., Chaves Loureiro, C., Cruz, A. A., Gemicioglu, B., Haahtela, T., Kupczyk, M., Kvedariene, V., Larenas-Linnemann, D. E., Okamoto, Y., Ollert, M., Pfaar, O., Pham-Thi, N. & Puggioni, F. & 49 others, Regateiro, F. S., Romantowski, J., Sastre, J., Scichilone, N., Taborda-Barata, L., Ventura, M. T., Agache, I., Bedbrook, A., Becker, S., Bergmann, K. C., Bosnic-Anticevich, S., Bonini, M., Boulet, L. P., Brusselle, G., Buhl, R., Cecchi, L., Charpin, D., de Blay, F., Del Giacco, S., Ivancevich, J. C., Jutel, M., Klimek, L., Kraxner, H., Kuna, P., Laune, D., Makela, M., Morais-Almeida, M., Nadif, R., Niedoszytko, M., Papadopoulos, N. G., Papi, A., Patella, V., Pétré, B., Rivero Yeverino, D., Robalo Cordeiro, C., Roche, N., Rouadi, P. W., Samolinski, B., Savouré, M., Shamji, M. H., Sheikh, A., Suppli Ulrik, C., Usmani, O. S., Valiulis, A., Yorgancioglu, A., Zuberbier, T., Fonseca, J. A., Costa, E. M. & Bousquet, J., 31 Dec 2025, In: Pulmonology. 31, 1, 2416869.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    10 Citations (Scopus)

  • Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK-air Study

    Sousa-Pinto, B., Costa, E. M., Vieira, R. J., Klimek, L., Czarlewski, W., Pfaar, O., Bedbrook, A., Amaral, R., Brussino, L., Kvedariene, V., Larenas-Linnemann, D. E., Iinuma, T., Pham-Thi, N., Regateiro, F. S., Taborda-Barata, L., Ventura, M. T., Ansotegui, I. J., Bergmann, K. C., Canonica, G. W. & Cardona, V. & 32 others, Cecchi, L., Cherrez-Ojeda, I., Cingi, C., Cruz, A. A., Del Giacco, S., Devillier, P., Fokkens, W. J., Gemicioglu, B., Haahtela, T., Ivancevich, J. C., Kuna, P., Kraxner, H., Laune, D., Louis, R., Makris, M., Morais-Almeida, M., Mösges, R., Niedoszytko, M., Papadopoulos, N. G., Patella, V., Pereira, A. M., Reitsma, S., Robles-Velasco, K., Rouadi, P. W., Samolinski, B., Sova, M., Toppila-Salmi, S. K., Sastre, J., Valiulis, A., Ollert, M., the MASK-air think tank & bousquet, J., Mar 2025, In: Clinical and Experimental Allergy. 55, 3, p. 226-238 13 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    1 Citation (Scopus)

  • Association of LEF1-AS1 with cardiovascular and neurological complications of COVID-19

    Vausort, M., Lumley, A. I., Boubakeur, H., Zhang, L., Hefeng, F. Q., Ollert, M., Wilmes, P., Fagherazzi, G. & Devaux, Y., Mar 2025, In: Journal of Molecular and Cellular Cardiology Plus. 11, 8 p., 100280.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
View all 217 research outputs