Projects per year
Organisation profile
Organisation profile
Full-fledged or partial technical biomarker validation, encompassing three modules:
- pre-analytical validation, to assess the most common pre-analytical variables undermining biomarker robustness
- analytical validation, to verify method fitness-for-purpose
- clinical verification, to perform a clinical validation on a smaller scale
Each module can be performed individually or in combination with another module.
Module sequence can be exchanged on a case-by-case BM scenario
Consultancy services for studies revolving around biomarker discovery, also in the context of grant applications Biomarker measurements, including platform bridging (ex.: qPCR to ddrPCR, ELISA to capillary Western Blot, etc.)
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Collaborations and top research areas from the last five years
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EPND: European platform for neurodegenerative disorders
Marchese, M. (PI)
1/11/21 → 31/10/26
Project: Research
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EATRIS-Plus: Consolidating the capacities of EATRIS-ERIC for Personalised Medicine
Ammerlaan, W. (PI), Marchese, M. (Partner), Beaumont, K. (Partner) & Nazarov, P. (Partner)
1/01/20 → 31/12/23
Project: Research
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Consensus guidelines for the validation of qRT-PCR assays in clinical research by the CardioRNA consortium
de Gonzalo-Calvo, D., Marchese, M., Hellemans, J., Betsou, F., Skov Frisk, N. L., Dalgaard, L. T., Lakkisto, P., Foy, C., Scherer, A., Garcia Bermejo, M. L., Devaux, Y. & EU-CardioRNA COST Action CA17129 (https://cardiorna.eu/), 10 Mar 2022, In: Molecular Therapy - Methods and Clinical Development. 24, p. 171-180 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access12 Citations (Scopus) -
Introduction of BD Vacutainer®Barricor™ tubes in clinical biobanking and application of amino acid and cytokine quality indicators to Barricor plasma
Knutti, N., Neugebauer, S., Scherr, F., Mathay, C., Marchese, M., Henry, E., Palm, J., Betsou, F. & Kiehntopf, M., 26 Apr 2022, In: Clinical Chemistry and Laboratory Medicine. 60, 5, p. 689-700 12 p.Research output: Contribution to journal › Article › Research › peer-review
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A cystatin C cleavage ELISA assay as a quality control tool for determining sub-optimal storage conditions of cerebrospinal fluid samples in alzheimer's disease research
Mommaerts, K., Willemse, E. A. J., Marchese, M., Larue, C., Van Der Flier, W. M., Betsou, F. & Teunissen, C. E., 2021, In: Journal of Alzheimer's Disease. 83, 3, p. 1367-1377 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus)