Proteins are the central players in cellular functions. They are functional units that are essential for cell structure. They are molecular machines, which can create power, regulate cellular signals or catalyze biochemical processes. Studying proteins can provide insight into what defines health and disease. We are using quantitative mass spectrometry-based proteomics as the central methodology of our research.  

We are interested in two central questions: First, how do post-translational modification alter the interaction network and the signaling of cellular systems and tissues, and second how we can use proteomic analysis to analyze patient samples to develop diagnostic markers.