Organisation profile
Organisation profile
As a collaboration between LIH and LNS, the main goal of the Center is to contribute to the partners’ respective and common translational transversal medicine research efforts and to provide sequencing capacity to internal and third party users.
The Center can be used as a service by either party, individually or jointly, or by a third party.
The Center is operated by a team composed of members from both partner organisations and led by an Operational Head of the Center, who will report to the LuxGen Steering Body.
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Collaborations and top research areas from the last five years
Profiles
Projects
- 1 Active
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GoE: Genome of Europe
Glod, F. (PI), Thien, H. (Partner), Klink, B. (Partner), Gantenbein, M. (Partner) & Malisoux, L. (Partner)
1/10/24 → 31/03/28
Project: Research
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DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks
Pinto, L. M., Pailas, A., Bondarchenko, M., Sharma, A. B., Neumann, K., Rizzo, A. J., Jeanty, C., Nicot, N., Racca, C., Graham, M. K., Naughton, C., Liu, Y., Chen, C. L., Meakin, P. J., Gilbert, N., Britton, S., Meeker, A. K., Heaphy, C. M., Larminat, F. & Van Dyck, E., 9 Feb 2024, In: Nucleic Acids Research. 52, 3, p. 1136-1155 20 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access16 Citations (Scopus) -
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Yabo, Y. A., Moreno-Sanchez, P. M., Pires-Afonso, Y., Kaoma, T., Nosirov, B., Scafidi, A., Ermini, L., Lipsa, A., Oudin, A., Kyriakis, D., Grzyb, K., Poovathingal, S. K., Poli, A., Muller, A., Toth, R., Klink, B., Berchem, G., Berthold, C., Hertel, F. & Mittelbronn, M. & 6 others, , 2 Apr 2024, In: Genome Medicine. 16, 1, 51.Research output: Contribution to journal › Article › Research › peer-review
Open Access34 Citations (Scopus) -
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation
Lind-Holm Mogensen, F., Sousa, C., Ameli, C., Badanjak, K., Pereira, S. L., Muller, A., Kaoma, T., Coowar, D., Scafidi, A., Poovathingal, S. K., Tziortziou, M., Antony, P. M. A., Nicot, N., Ginolhac, A., Vogt Weisenhorn, D. M., Wurst, W., Poli, A., Nazarov, P. V., Skupin, A. & Grünewald, A. & 1 others, , 16 Jul 2024, In: Journal of Neuroinflammation. 21, 1, 174.Research output: Contribution to journal › Article › Research › peer-review
Open Access18 Citations (Scopus)