Luxembourg Institute of Health

Research output

Research output per year 1978 2016 2017 2018 2019 2020 2021 2022 2022

• 2294 Article
• 400 Review article
• 144 Chapter
• 141 Abstract
• 532 More
  • 98 Comment/debate
  • 89 Commissioned report
  • 86 Letter
  • 78 Editorial
  • 57 Doctoral Thesis
  • 27 Book
  • 18 Conference contribution
  • 18 Short survey
  • 17 Patent
  • 16 Preprint
  • 13 Conference article
  • 4 Foreword/postscript
  • 4 Poster
  • 4 Other contribution
  • 2 Digital or Visual Products
  • 1 Meeting Abstract

Research output per year

Research output per year

Search results

• 2021

  A DNA Damage Repair Signature in Pediatric High-Grade Gliomas: XRCC1 and PARP1, Key Biomarkers

  Entz-Werle, N., Poidevin, L., Nazarov, P., Lhermitte, B., Poch, O., Dontenwill, M. & Van Dyck, E., Nov 2021, p. S59-S59.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Allergic airway inflammation impacts tumor take and delays experimental glioblastoma progression

  Poli, A., Oudin, A., Muller, A., Hunewald, O., Domingues, O., Nazarov, P. V., Puard, V., Baus, V., Azuaje, F., Dittmar, G., Zimmer, J., Michel, T., Niclou, S. P. & Ollert, M., Sep 2021, p. 3-4.

  Research output: Contribution to conference › Abstract › peer-review

• Allergy burden in luxembourg: A population-based, cross-sectional health survey paralleled by component-resolved-IgE-diagnosis

  Czolk, R., Roth, L. E., Scheuermann, T., Graf, T., Klueber, J., Hilger, C., Roesch, N., Le Coroller, G., Vaillant, M., Ruiz-Castell, M., Fagherazzi, G., Huiart, L., Ollert, M. & Kuehn, A., Nov 2021, p. 429-429.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Animal allergen exposure levels in veterinary practices and homes of practice employees

  Zahradnik, E., Sander, I., Kleinmueller, O., Lotz, A., Liebers, V., Janssen-Weets, B., Kler, S., Hilger, C., Beine, A., Hoffmeyer, F., Nienhaus, A. & Raulf, M., Feb 2021, p. 152-152.

  Research output: Contribution to conference › Abstract › peer-review

• A toolbox enabling a data-driven selection of regions of interest in tumor tissue sections for imaging mass cytometry analysis.

  Schulz, D., Renaud-Tissot, S., Liechti, R., Eling, N., Daniel, M., Windhager, J., Karapetyan, Y., Mrowiec, T., Rusakiewicz, S., Hong, H. S., Morfouace, M. & Bodenmiller, B., Jul 2021.

  Research output: Contribution to conference › Abstract › peer-review

• Beliefs and attitudes towards an ehealth tool to improve medication adherence in breast cancer survivors

  Goetzinger, C., Vrijens, B., Fagherazzi, G., Preau, M., Mancini, J., Ben-Diane, M. K. & Huiart, L., Feb 2021, p. 293-293.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Declining incidence of HIV multidrug resistance in Europe

  Dewandre, J., Vercauteren, J., Vandamme, A. -M., Icarndona, F., Rossetti, B., Fabbiani, M., Abecasis, A., Devaux, C., Kaiser, R., Sonnerborg, A. & Zazzi, M., Oct 2021, p. 25-26.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Effects of alpha-synuclein on astrocytic-neuronal crosstalk

  Mulica, P., Pereira, S., Delcambre, S., Venegas, C., Krueger, R. & Gruenewald, A., Jul 2021, p. E221-E221.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Epigenetic regulation via PRMT7 controls monocyte migration and COPD pathogenesis

  Conlon, T., Gunes, G., Kim, A. J. R., Burgstaller, G., Verleden, S., Stoeger, T., Dittmar, G., Koenigshoff, M., Eickelberg, O., Watz, H., Schneider, R. & Yildirim, A. O., 5 Sep 2021.

  Research output: Contribution to conference › Abstract › peer-review

• Illuminating the signaling enigma of Carvedilol

  Benkel, T., Zimmermann, M., Monteleone, S., Lim, V., Pavlaki, N., Malan, D., Matthees, E., Szpakowska, M., Miess, E., Zeiner, J., Haeberlein, F., Simon, K., Gomeza, J., Inoue, A., Schulz, S., Chevigne, A., Hoffmann, C., Sasse, P., Nikolaev, V., Kolb, P., & 2 othersWaldhoer, M. & Kostenis, E., Mar 2021, p. S22-S22.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Inhibition of GBM invasion by the A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid (AMPA) Glutamate receptor antagonist Perampanel

  Sarnow, K., Kanli, G., Keunen, O. & Bjerkvig, R., 9 Sep 2021, p. 10-10.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Loss of williams syndrome transcription factor (WSTF) leads to improved temozolomide sensitivity in human glioblastoma cells irrespective of MGMT expression

  Sarnow, K., Schwab, S. G., Rio, O., Mukherjee, J., Bjerkvig, R. & Johannessen, T. A., Sep 2021, p. 56-56.

  Research output: Contribution to conference › Abstract › peer-review

• Metastatic potential of systemic glioblastoma stem cell lines in vivo

  Schwab, S. G., Sarnow, K., Thorsen, F. A., Hossain, J. A., Goldbrunner, R., Miletic, H. & Bjerkvig, R., Sep 2021, p. 36-36.

  Research output: Contribution to conference › Abstract › peer-review

• Mondo-A Maintains Aggressiveness in Common Acute Lymphoblastic Leukemia (B-All) by Modulating the Metabolic Stress Response and can be Targeted by a Designer Drug

  Sipol, A., Hameister, E., Xue, B., Hofstetter, J., Barenboim, M., Ollinger, R., Prexler, C., Franchina, D., Petry, A., Thiel, U., Gorlach, A., Cario, G., Brenner, D., Richter, G., Grunewald, T., Rad, R., Wolf, E., Ruland, J., Sorensen, P. & Burdach, S., Nov 2021, p. S161-S162.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Multiomic single nucleus RNA- and ATACSEQ profiling reveals regulators of glioma cell state diversity

  Anderson, K., Johnson, K., Varn, F., Bessonett, S., Gujar, A., Flynn, B., Courtois, E., Hau, A-C., Golebiewska, A., Paek, S. H., Niclou, S., Samuels, M., Robson, P. & Verhaak, R., Nov 2021, p. 4-4.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• New section on carbohydrate epitopes in the WHO/IUIS allergen nomenclature website

  Jappe, U., Platts-Mills, T. A., Hilger, C., Van Hage, M., Gadermaier, G., Spillner, E., Lidholm, J., Aalberse, R. C., Van Ree, R., Goodman, R. E. & Pomes, A., Nov 2021, p. 168-168.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Novel thioridazine derivates: antiproliferative and apoptosis-inducing activity on glioblastoma cells in vitro

  Schwab, S. G., Sarnow, K., Alme, E., Goldbrunner, R., Bjorsvik, H. & Bjerkvig, R., Sep 2021, p. 34-34.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Phenotypic heterogeneity and plasticity as resistance mechanisms in glioblastoma

  Yabo, Y. Y., Oudin, A., Skupin, A., Nazarov, P. V., Niclou, S. P. & Golebiewska, A., Sep 2021, p. 1-1.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Raman spectroscopy as a diagnostic tool in neuropathology

  Klamminger, G. G., Mombaerts, L., Klein, K., Jelke, F., Mirizzi, G., Slimani, R., Gerardy, J-J., Husch, A., Hertel, F., Mittelbronn, M. & Borgmann, F. K., Nov 2021, p. 125-125.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Raman spectroscopy as a tool in neurosurgery

  Borgmann, F. K., Klamminger, G. G., Mombaerts, L., Klein, K., Jelke, F., Mirizzi, G., Slimani, R., Pilot, M., Husch, A., Mittelbronn, M. & Hertel, F., Nov 2021, p. 125-125.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Re-Irradiation with high-dose stereotactic radiotherapy for recurrent High-grade Gliomas

  Mousli, A., Bocquet, V., Frederick, B., Louis, C., Biver, S., Philippi, S., Nickers, P., Untereiner, M. & Vogin, G., Aug 2021, p. S864-S864.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• The circadian clock remains intact, but with dampened hormonal output in heart failure

  Crnko, S., Printezi, M., Leiteris, L., Lumley, A. I., Zhang, L., Ernens, I., Van Faassen, M., Du Pre, B. C., Kemperman, H., Zwetsloot, P. P. M., Oerlemans, M. I. F. J., Doevendans, P. A. F. M., Sluijter, J. P. G., Devaux, Y. & Van Laake, L. W., Sep 2021, p. 18-19.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• The gut commensal Bacteroides vulgatus mpk reduces Candida albicans pathogenicity towards epithelial cells

  Niemiec, M. J., Hammer, M., Auge, I., van Leeuwen, P., Gorki, F., Walker, A., Steimle, A., Frick, J. S. & Jacobsen, I. D., Sep 2021, p. 10-10.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• The role of IDH1 R132H mutation in glioma an investigation by genome-editing in human induced pluripotent stem cells

  Kopp, A., Gawehn, L., William, D., Preussler, M., Richter, S., Heide, M., Marrone, L., Thieme, A., Borgmann, F. K., Mittelbronn, M., Capper, D., Schrock, E. & Klink, B., Nov 2021, p. 217-217.

  Research output: Contribution to conference › Abstract › peer-review

• Vicilin IgE-cross-reactivity is responsible for in vitro allergenicity to cowpea in patients with legume allergy

  Chentouh, M. M., Boutebba, A., Kler, S., Revets, D., Swiontek, K., Kluebers, J., Kuehn, A., Ollert, M., Codreanu-Morel, F. & Hilger, C., Nov 2021, p. 400-400.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access
• 2020

  4-miRNA signature and MGMT promoter methylation improve risk stratification in glioblastoma.

  Unger, K., Fleischmann, D. F., Ruf, V., Felsberg, J., Piehlmaier, D., Samaga, D., Hess, J., Mittelbronn, M., Lauber, K., Budach, W., Sabel, M., Roedel, C., Reifenberger, G., Herms, J., Tonn, J., Zitzelsberger, H., Belka, C. & Niyazi, M., Nov 2020, p. S169-S170.

  Research output: Contribution to conference › Abstract › peer-review

• Biotin interference can cause false-negative IgE test results in patients with anaphylaxis

  Scheib, N., Bauersachs, D., Heinrich, C. M., Pogorelov, D., He, F., Bindslev-Jensen, C., Skevaki, C. & Ollert, M., Aug 2020, p. 70-71.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Circular RNAs as prognostic biomarkers after cardiac arrest

  Stefanizzi, F., Zhang, L., Nielsen, N., Devaux, Y. & Salgado-Somoza, A., Nov 2020, p. 3660-3660.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Deep serum IgE-profiling in a Luxembourgish cohort of peanut-allergic children diagnosed by oral food challenge

  Czolk, R., Klueber, J., Scheuermann, T., Wilmes, P., Bindslev-Jensen, C., Codreanu-Morel, F., Ollert, M. & Kuehn, A., Aug 2020, p. 581-582.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Dianhydrogalactitol (VAL-083) exhibits strong efficacy in GBM tumors with different (epi)genetic background and treatment history

  Golebiewska, A., Oudin, A., Baus, V., Hau, A-C., Klein, E., Steino, A., Bacha, J. A., Niclou, S. P. & Brown, D. M., Aug 2020.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Effects of the neurotrophic factor Neurturin on epithelial barrier disruption in the context of asthma

  Morel, L., Domingues, O., Zimmer, J. & Michel, T., Aug 2020, p. 385-385.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Evolution of multimorbidity patterns and their association with quality of life: findings from SHARE

  Makovski, T., Schnell, M., Huiart, L. & van den Akker, M., Oct 2020, p. S33-S34.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access
  1 Citation (Scopus)

• Identifying GDF-15 as potential novel immunotherapeutic target linked to immune cell exclusion in tumors and resistance to anti-PD-1 treatment

  Wischhusen, J., Wistuba-Hamprecht, K., Harter, P. N., Cheng, P., Martens, A., Gogolla, F., Nonomura, Y., Romer, P., Koch, S. D., Haake, M., Schuberth-Wagner, C., Rudiger, M., Leo, E., Mittelbronn, M., Levesque, M. P., Hackl, H., Dummer, R. & Weide, B., Aug 2020.

  Research output: Contribution to conference › Abstract › peer-review

• Interrogating intratumoral transcriptomic heterogeneity and plasticity as resistance mechanisms in glioblastoma

  Yabo, Y. A., Arns, T., Oudin, A., Grzyb, K., Poovathingal, S., Michelucci, A., Skupin, A., Niclou, S. P. & Golebiewska, A., Nov 2020, p. 198-198.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Mitochondrial-specific polygenic risk score is associated with increased Parkinson's disease risk

  Landoulsi, Z., Bobbili, D., Pachcheck, S., Arena, G., Kruger, R. & May, P., Dec 2020, p. 410-410.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Mucus barrier erosion by the commensal gut microbiome leads to exacerbated food allergy sensitization

  Parrish, A. L., Willieme, S., Neumann, M., Leonard, C., Ollert, M. & Desai, M., Aug 2020, p. 252-253.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Multimorbidity patterns and quality of life across European populations: Results from SHARE database

  Makovski, T. T., Poblador Plou, B., Schnell, M., Stranges, S., Zeegers, M., Le Coroller, G., Huiart, L. & van den Akker, M., Sep 2020, p. V244-V244.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Musculoskeletal disorders (MSKDS) are very frequent in patients with T1D, are associated with diabetes complications and can impair the ability to use diabetes technology

  Picard, S., Vasilevski, D. & Fagherazzi, G., 1 Feb 2020, p. A233-A233.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access
  6 Citations (Scopus)

• Night shift work, sleep quality and risk of endocrine-related cancer: a systematic review

  Ling, L., Shah, S., Hussain, J., Stranges, S. & Anderson, K., Sep 2020, p. V956-V956.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Overcoming preanalytical variabilities for peripheral blood mononuclear cells and exosome profiling in the IMMUcan multicentre study

  Mustapha, R., Pomella, V., Vicencio, J., Lopez-Lastra, S., Bahlawane, C., Ammerlaan, W., Hong, H. S., Morfouace, M., Vallely-Gilroy, C., Soumelis, V., Romano, E., Tejpar, S., Ng, T. & Betsou, F., Aug 2020.

  Research output: Contribution to conference › Abstract › peer-review

• Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine

  Golebiewska, A., Hau, A-C., Oudin, A., Stieber, D., Yabo, Y. A., Kwon, Y-J., Klink, B., Skupin, A., Hertel, F., Bjerkvig, R. & Niclou, S. P., Nov 2020, p. 229-229.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Programme demence prevention (PDP) : a nation-wide programme for dementia prevention in luxembourg

  Schroder, V., Kemp, J., Kaysen, A., Fritz, J. V., Wagner, S., Kohler, S., Leist, A., Kalbe, E. & Kruger, R., Oct 2020, p. 6-7.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Repositioned Drugs for Targeted Therapy of Biomarker Driven Cancer Metastasis

  Kobelt, D., Manisha, J., Sack, U., Perez-Hernandez, D., Zincke, F., Gohlke, B., Dahlmann, M., Liebeskind, J. M., Robert, P., Peter, V. K. J., Dittmar, G., Lewis, J., Walther, W. & Stein, U., Feb 2020, p. 203-203.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Risk and prevention of dementia: from observation to implementation

  Kohler, S., Deckers, K., Richard, E. & Kruger, R., Oct 2020, p. 3-4.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Sleep difficulties and alcohol use behaviors in adolescents and young adults: a systematic review

  Hussain, J., Ling, L., Stranges, S. & Anderson, K. K., Sep 2020.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Socioeconomic status and stroke incidence, prevalence, mortality and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

  Avan, A., Digaleh, H., Di Napoli, M., Stranges, S., Behrouz, R., Shojaeianbabaei, G., Amiri, A., Tabrizi, R., Mokhber, N., Spence, J. D. & Azarpazhooh, M. R., 14 Apr 2020.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Statins and breast cancer risk in a cohort of postmenopausal women

  Dossus, L., Chajes, V., His, M., Cairat, M., Al-Rahmoun, M., Fagherazzi, G., Severi, G., Gunter, M. J. & Fournier, A., Oct 2020, p. 572-572.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access
  1 Citation (Scopus)

• Successful CpG/Fel d 1-based immunotherapy reduces Th2 effector and memory cell compartments in a mouse model of allergic asthma

  Montamat, G., Leonard, C., Domingues, O., Davril, C. & Ollert, M., Aug 2020, p. 97-98.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• Targetable FGFR3 Fusions and Novel FGFR3 Mutations in Glioma

  Schittenhelm, J., Ziegler, L., Mittelbronn, M., Capper, D., Burghardt, I., Poso, A., Biskup, S., Skardelly, M. & Tabatabal, G., Feb 2020, p. 33-33.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access
• 2019

  A 3D brain organoid coculture system delineates the invasive cell components in glioblastoma

  Zhou, W., Klink, B., Dittmar, G., Nazarov, P., Garcia, E. M., Han, M., Lunavat, T. R., Joesph, J. V., Saed, H. S., Bahador, M., Wang, J. & Bjerkvig, R., Aug 2019, p. 56-57.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access