Projects per year
Organisation profile
Organisation profile
The goal of the Infection and Immunotherapy Research (IIR) is to develop new immunotherapies against infectious diseases and cancer. They aim to provide a new translational understanding on HIV cure, bacterial infections and of cancer immunology. The group is also involved in clinical research working towards the elimination of HIV and Hepatitis in Luxembourg.
Aims and objectives
We focus on the development of immunotherapeutic complexes and NK cell engagers boosting innate immunity against viruses, bacteria and cancer cells for further elimination by the immune system. Our research encompasses protein engineering, virology, bacteriology, immunoassays and preclinical studies for the design of targeted therapeutic approaches.
HIV and viral hepatitis elimination
Our group support the monitoring of HIV and Hepatitis elimination in Luxembourg, as part of international research and surveillance networks, through outreach projects and clinical studies from the national HIV and Hepatitis programmes.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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PSEUDO: Pre-clinical validation of CoMiX and Bikes/Trikes against infections with Pseudomonas aeruginosa
Seguin-Devaux, C. (PI), Zimmer, J. (Partner), Si-Tahar, M. (Partner) & Pitiot, A. (Partner)
FNR - Fonds National de la Recherche
1/02/23 → 30/04/26
Project: Research
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ROSETTA: A global registry on second generation and long-acting integrase inhibitor failures.
Seguin-Devaux, C. (PI)
1/01/22 → 30/11/25
Project: Research
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I2TRON Camille Rolin: Pre-clinical evaluation of immunoconjugates activating NK cells in cancer models
Seguin-Devaux, C. (PI) & Rolin, C. (PhD Student)
FNR - Fonds National de la Recherche
1/09/21 → 31/08/25
Project: Research
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Adoptive T Regulatory Cell Therapy Takes an Important Step
Seguin-Devaux, C. & Zimmer, J., Jun 2024, In: NEJM evidence. 3, 6, p. EVIDe2400109Research output: Contribution to journal › Editorial
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Bridging the gap with multispecific immune cell engagers in cancer and infectious diseases
Rolin, C., Zimmer, J. & Seguin-Devaux, C., Jul 2024, In: Cellular and Molecular Immunology. 21, 7, p. 643-661 19 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Direct-acting antiviral therapies for hepatitis C infection: global registration, reimbursement, and restrictions
Marshall, A. D., Willing, A. R., Kairouz, A., Cunningham, E. B., Wheeler, A., O'Brien, N., Perera, V., Ward, J. W., Hiebert, L., Degenhardt, L., Hajarizadeh, B., Colledge, S., Hickman, M., Jawad, D., Lazarus, J. V., Matthews, G. V., Scheibe, A., Vickerman, P., Dore, G. J. & Grebely, J. & 31 others, , Apr 2024, In: The Lancet Gastroenterology and Hepatology. 9, 4, p. 366-382 17 p.Research output: Contribution to journal › Review article › peer-review
9 Citations (Scopus)