Projects per year
Organisation profile
Organisation profile
The goal of the Infection and Immunotherapy Research (IIR) is to develop new immunotherapies against infectious diseases and cancer. They aim to provide a new translational understanding on HIV cure, bacterial infections and of cancer immunology. The group is also involved in clinical research working towards the elimination of HIV and Hepatitis in Luxembourg.
Aims and objectives
We focus on the development of immunotherapeutic complexes and NK cell engagers boosting innate immunity against viruses, bacteria and cancer cells for further elimination by the immune system. Our research encompasses protein engineering, virology, bacteriology, immunoassays and preclinical studies for the design of targeted therapeutic approaches.
HIV and viral hepatitis elimination
Our group support the monitoring of HIV and Hepatitis elimination in Luxembourg, as part of international research and surveillance networks, through outreach projects and clinical studies from the national HIV and Hepatitis programmes.
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Collaborations and top research areas from the last five years
Profiles
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PSEUDO: Pre-clinical validation of CoMiX and Bikes/Trikes against infections with Pseudomonas aeruginosa
Seguin-Devaux, C. (PI), Zimmer, J. (Partner), Si-Tahar, M. (Partner) & Pitiot, A. (Partner)
FNR - Fonds National de la Recherche
1/02/23 → 30/04/26
Project: Research
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ROSETTA: A global registry on second generation and long-acting integrase inhibitor failures.
Seguin-Devaux, C. (PI)
1/01/22 → 30/11/25
Project: Research
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I2TRON Camille Rolin: Pre-clinical evaluation of immunoconjugates activating NK cells in cancer models
Seguin-Devaux, C. (PI) & Rolin, C. (PhD Student)
FNR - Fonds National de la Recherche
1/09/21 → 31/08/25
Project: Research
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Fighting Antibiotic Resistance: Insights Into Human Barriers and New Opportunities: Antibiotic Resistance Constantly Rises With the Development of Human Activities. We discuss Barriers and Opportunities to Get It Under Control
Pitiot, A., Rolin, C., Seguin-Devaux, C. & Zimmer, J., Jun 2025, In: BioEssays. 47, 6, e70001.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Flow cytometry conjugate formation assay between natural killer cells and their target cells
Iserentant, G., Seguin-Devaux, C. & Zimmer, J., 5 Feb 2025, In: Methods in Cell Biology. 193, p. 213-228Research output: Contribution to journal › Article › Research › peer-review
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Adoptive T Regulatory Cell Therapy Takes an Important Step
Seguin-Devaux, C. & Zimmer, J., Jun 2024, In: NEJM evidence. 3, 6, p. EVIDe2400109Research output: Contribution to journal › Editorial