The Group of Immune Systems Biology (GISB) focuses on unravelling how the dynamic molecular networks of immune cells quantitatively, rather than simply all-or-none, respond to various genetic perturbations/mutations as well as environmental stresses under physiological or pathological conditions.  

To this end, the GISB develops and applies integrated computational and experimental systems biology strategies to predict and delineate the dynamic molecular networks of immune cells using both patients' samples and mouse disease models. With expertise in both large-scale network analysis and immunology, we orchestrate major efforts on data-driven and network-biology guided experiments in order to accelerate biomedical discoveries, especially in systems immunology and aging related diseases.