Organisation profile
Organisation profile
The HBRU primary goals are the development of biomarkers for the identification of human exposure to different occupational and environmental pollutants such as pesticides, polycyclic aromatic hydrocarbons and persistent organic pollutants. Furthermore, HBRU aims to expand existing knowledge of the relationships between exposure to pollutants and subsequent biological/biochemical disorders.
HBRU analytical techniques are mainly based on chromatography coupled with tandem mass spectrometry applied to various biological matrices such as blood, urine and hair. HBRU also has strong expertise in biomarkers of alcohol consumption as well as in the assessment of exposure to cigarette smoke in active and passive smoking.
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Collaborations and top research areas from the last five years
Profiles
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CARCICHEM: Tracking Exposure to Carcinogenic Chemicals in Luxembourg with Multi-Matrix Approach
Appenzeller, B. (PI) & Fabris, A. (Partner)
1/03/26 → 29/02/28
Project: Research
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Xpose (Paula Llabres Piza): Hormonal profile in hair for subject characterization and indication of early biological response to exposome
Appenzeller, B. (PI) & Llabres Piza, P. (PhD Student)
FNR - Fonds National de la Recherche
15/01/25 → 14/01/29
Project: Research
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27th Meeting of the Society of Hair Testing (SoHT)
Favretto, D., Rossi, S., Appenzeller, B. & Cirimele, V., Mar 2026, In: Drug Testing and Analysis. 18, 3, p. 332-333 2 p.Research output: Contribution to journal › Editorial
Open Access -
Mapping the human chemical exposome for public health
David, A., Lennon, S., Mercier, F., Bouhlel, J., Chaker, J., Appenzeller, B. M. R., Audouze, K., Ayeni, K. I., Bailly-Chouriberry, L., El Balkhi, S., Barouki, R., Belova, L., Benmarhnia, T., Bonnefille, B., Bessonneau, V., Bonvallot, N., Bouchart, V., Bouvier-Capely, C., Buisson, C. & Bury, D. & 38 others, , 18 Mar 2026, In: Nature Medicine. 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Citation (Scopus) -
Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay
Benitez Leite, S., Iglesias-Gonzalez, A., Mesquita, M., Macchi, M., Mesnage, R. & Appenzeller, B. ., Mar 2026, In: Drug Testing and Analysis. 18, 3, p. 354-369 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access