DNA Repair and Chemoresistance

Websitehttps://www.lih.lu/en/research-scope/research-department/department-of-cancer-research/dna-repair-and-chemoresistance/

5 Active
6 Finished

11 results

Active

PIANO: Impact of intratumoral heterogeneity on treatment resistance and tumor relapse in glioblastoma
Van Dyck, E. (PI), Mittelbronn, M. (CoPI), Rogister, B. (CoPI), Neirinckx, V. (CoPI) & Torres Fernández, M. (PhD Student)
15/11/23 → 30/11/25
Project: Research
CANBIO2 (Ana Catarina Almeida): Harnessing DNA repair factors to promote an innate immune response against glioblastoma
Van Dyck, E. (PI) & Almeida, A. C. (PhD Student)
FNR - Fonds National de la Recherche
1/09/23 → 31/08/27
Project: Research
ATLANTIS: Targeting homologous recombination and replication stress in glioblastoma: from molecular insights to synthetic lethality approaches
Van Dyck, E. (PI) & Yi, T. (PhD Student)
FNR - Fonds National de la Recherche, Action LIONS Vaincre le Cancer
1/03/23 → 28/02/27
Project: Research
SUNRISE (TLV-PDR-2021): TARGETING TUMOR PROPAGATING CELLS IN GLIOBLASTOMA: FROM MECHANISTICINSIGHTS TO PRECISION MEDICINE
Van Dyck, E. (PI), Rogister, B. (CoPI), Neirinckx, V. (CoPI), Nazarov, P. (CoPI) & Pailas, A. (PhD Student)
Fondation du Pélican de Mie et Pierre Hippert-Faber, FNRS - Fonds National de la Recherche Scientifique
1/03/22 → 28/02/26
Project: Research
NIMBUS: Roles of the epigenetic reader MBD1 in IDH1-mutated gliomas
Van Dyck, E. (PI), Fritah, S. (CoPI) & Tourneur, L. (PhD Student)
FNRS - Fonds National de la Recherche Scientifique
17/01/22 → 16/10/26
Project: Research
Finished
TERMINI: Roles of NEIL3 DNA glycosylase in telomere dynamics and DNA demethylation in glioblastoma: From molecular insights topreclinical target validation
Van Dyck, E. (PI) & Baidarjad, H. (PhD Student)
FNR - Fonds National de la Recherche, Lions Clubs International
1/07/21 → 30/09/24
Project: Research
DANTE: Harnessing DNA repair factors to promote an innate immune response against glioblastoma: an invitro RNAi screen selecting phagocytosis promoting genes in glioblastoma cells
Van Dyck, E. (PI), Michelucci, A. (CoPI), Nazarov, P. (Partner), Skupin, A. (Partner) & Mittelbronn, M. (Partner)
Fondation de Luxembourg
1/01/20 → 31/12/21
Project: Research
PAELLA: A NOVEL PERSONALIZED STRATEGY TARGETING DNA REPAIR PATHWAY ADDICTIONS IN GLIOBLASTOMA: FROM PATIENT STRATIFICATION TO PRECLINICAL VALIDATION
Van Dyck, E. (PI)
Lions Clubs International
1/01/20 → 31/12/21
Project: Research
Modulators of chemoresistance in GBM: DNA repair mechanisms as molecular determinants of glioblastomachemoresistance: in vitro investigation and characterization of novel animalmodels
Van Dyck, E. (PI) & Niclou, S. (CoPI)
FNRS - Fonds National de la Recherche Scientifique
1/10/19 → 30/09/21
Project: Research
CANBIO (Lia Pinto): Targeting DNA repair mechanisms in primary glioblastoma and their recurrences: from basic mechanisms to pre-clinical aspects and personalized therapy
Van Dyck, E. (PI) & Pinto, L. (PhD Student)
FNR - Fonds National de la Recherche
1/11/17 → 31/10/21
Project: Research
MGMT, GBM development and TMZ resistance: Impact of MGMT on tumor development and resistance to temozolomide inglioblastoma: in vitro and in vivo characterization using novel GBM models
Van Dyck, E. (PI) & Bjerkvig, R. (CoPI)
FNRS - Fonds National de la Recherche Scientifique
1/02/17 → 31/01/19
Project: Research