Department of Infection and Immunity

Luxembourg Institute of Health

Websitehttps://www.lih.lu/en/research-scope/research-department/department-of-infection-and-immunity/

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LS_DII 2024: Lecture series in infection and immunity
Brenner, D. (PI)
FNR - Fonds National de la Recherche
1/01/24 → 31/12/24
Project: Research
NanoLux platform: NanoLux platform
Chevigne, A. (PI) & Szpakowska, M. (CoPI)
Luxembourg Institute of Health
1/01/23 → 31/12/24
Project: Research
LS-DII 2023: Lecture Series in Infection & Immunity 2023
Brenner, D. (PI) & Ollert, M. (CoPI)
1/01/23 → 31/12/23
Project: Research
Antibody-CoV-ID: Development and validation of a SARS-CoV-2 variant surrogate Viral Neutralization Test (sVNT)
Seguin-Devaux, C. (PI)
European Commission
8/12/22 → 30/04/23
Project: Research
LSMOT2: Lecture series on multi-omics techniques
Dittmar, G. (PI)
1/12/22 → 30/11/23
Project: Research
EAACI-TNFR2: Use of TNFR2 agonist antibody to enhance potent regulatory T cells in allergen-specific immunotherapy
Bazon, M. (PI) & Ollert, M. (Scientific Advisor/Mentor)
European Academy of Allergy and Clinical Immunology (EAACI)
1/10/22 → 31/03/23
Project: Research
PYRAIMD: Deciphering the Function of Mitochondrial Pyruvate Transport in T Cell-Mediated Immunity
Horkova, V. (CoPI) & Brenner, D. (PI)
EMBO
1/10/22 → 30/09/24
Project: Research
Conolidine (TLV-2022-PDR): Regulation of glioblastoma growth and tumor microenvironment by receptors ACKR3 and CXCR4
Szpakowska, M. (CoPI) & Chevigne, A. (PI)
1/10/22 → 30/09/24
Project: Research
VIRALERT: Environmental-based epidemiology for preparedness and early detection of viral epidemics
Ogorzaly, L. (PI) & Snoeck, C. (CoPI)
FNR - Fonds National de la Recherche
1/01/22 → 31/12/24
Project: Research
LS-DII 2022: Lecture Series in Infection & Immunity 2022
Brenner, D. (PI) & Ollert, M. (PI)
FNR - Fonds National de la Recherche
1/01/22 → 31/12/22
Project: Research
InProFluD: Developing an integrated approach to assess the emergence threat associated with influenza D viruses’ circulating in Europe
Ducatez, M. F. (PI), Snoeck, C. (CoPI), Zohari, S. (CoPI), Saegerman, C. (CoPI), Moreno, A. (CoPI) & Quinnes, E. (CoPI)
European Food Safety Authority
10/11/21 → 9/11/23
Project: Research
LSMOT: Next-generation of multi-omics research: going to the single cell
Dittmar, G. (PI)
FNR - Fonds National de la Recherche
1/09/21 → 31/08/22
Project: Research
MEGAKINE: Megakines - novel tools for structural insight into receptor:chemokine complexes
Uchanski, T. (PI) & Chevigne, A. (CoPI)
European Commission
1/09/21 → 4/01/22
Project: Research
EXOKINE (ACKR3/CXCR7): Unraveling the role of the ACKR3/CXCR7 receptor in glioblastoma cells survival and invasion in the tumor relapse.
Rogister, B. (PI), Chevigne, A. (CoPI) & Szpakowska, M. (CoPI)
FNRS - Fonds National de la Recherche Scientifique
1/07/21 → 30/11/23
Project: Research
MUCO-IMMUN: MUCOBIOME-MEDIATED IMMUNE PATHWAYS IN INFLAMMATORY BOWEL DISEASES
Desai, M. (PI) & Boudaud, M. (CoPI)
European Commission
1/05/21 → 30/04/23
Project: Research
INTERACTINg: Targeting a key promoter of multiple pro-metastatic pathways in breast cancer
Thomas, C. (PI), Dittmar, G. (PI) & Berro, F. (PhD Student)
FNRS - Fonds National de la Recherche Scientifique
1/03/21 → 28/02/23
Project: Research
Lux-FiCo: From mouse to man: translating findings in mouse study into a human cohort (Luxembourgish Fiber Cohort: Lux-FiCo)
Desai, M. (PI), Bohn, T. (Partner) & Ollert, M. (Partner)
Personalised Medicine Consortium (PMC)
1/01/21 → 30/06/22
Project: Research
Prévention transmission covid-19
Seguin-Devaux, C. (PI)
Ministry of Health
9/10/20 → 31/12/22
Project: Research
ALAC: Age Acceleration and the Life Course
D’Ambrosio, C. (PI), Turner, J. (CoPI) & Holuka, C. (PhD Student)
FNR - Fonds National de la Recherche
1/09/20 → 30/09/24
Project: Research
NanoLux SARS-CoV-2: Assessment of SARS-CoV-2neutralizing antibodies inLuxembourg through novel highlysensitive NanoLuciferase-basedhigh throughput assays
Chevigne, A. (PI) & Ollert, M. (CoPI)
FNR - Fonds National de la Recherche, Laboratoires Réunis S.A.
1/09/20 → 14/07/23
Project: Research
COMPARE: Comparing the technical performances of three real-time PCRs to counteract the COVID-19 outbreak in Luxembourg
Seguin-Devaux, C. (PI) & Abdelrahman, T. (CoPI)
FNR - Fonds National de la Recherche
1/07/20 → 28/02/21
Project: Research
COV-Array: Coronavirus antigen array for parallelized serological profiling
Longworth, J. (PI) & Dittmar, G. (PI)
FNR - Fonds National de la Recherche
1/07/20 → 28/02/21
Project: Research
FunBiome: Functional characterization of COVID-19 patient gut microbiome
Desai, M. (PI)
FNR - Fonds National de la Recherche
1/06/20 → 31/03/21
Project: Research
COLIVE*: Role of COmpanion and LIVEstock animals in the epidemiology of SARS-CoV
Snoeck, C. (PI)
FNR - Fonds National de la Recherche
1/06/20 → 31/03/21
Project: Research
CORONASTEP+: The value of sewage surveillance to provide new insights on the circulation of SARS-COV-2 and to reveal the true extent of the coronavirus pandemic at the national scale
Ogorzaly, L. (PI), Snoeck, C. (CoPI), Martin-Gallausiaux, C. (Participant) & Fournier, G. (Participant)
FNR - Fonds National de la Recherche
1/06/20 → 31/03/21
Project: Research
CovSerum: Early detection of COVID19-induced tissue damage and (hyper)inflammation from serum samples
Dittmar, G. (PI) & Behrmann, I. (CoPI)
FNR - Fonds National de la Recherche
1/06/20 → 31/03/21
Project: Research
NEUTRACOV: A novel high throughput assay to measure plasma NEUTRalizing Activity against SARS-CoV-2 against SARS-CoV-2
PerezBercoff, D. (PI)
FNR - Fonds National de la Recherche, Rotary Clubs de Luxembourg
1/06/20 → 30/11/20
Project: Research
SMART GLIOBLASTOMA: SMART GLIOBLASTOMA: Signaling and Modulation of the AtypicalIsoform of the CXCR3 RecepTor in glioblastoma cells
Chevigne, A. (PI), Niclou, S. (PI), Rogister, B. (PI), Hanson, J. (PI) & D'Uonnolo, G. (PhD Student)
FNRS - Fonds National de la Recherche Scientifique
15/05/20 → 14/10/24
Project: Research
Opiokine: Multidimensional regulation of the opioid network by ACKR3
Chevigne, A. (PI), Szpakowska, M. (CoPI) & Palmer, C. (PhD Student)
FNR - Fonds National de la Recherche
15/05/20 → 14/05/24
Project: Research
COV-Immun: Development of a high performance COVID-19 immunoassay, an essential tool to establish immunity passports in the Luxembourgish population
Hilger, C. (PI)
FNR - Fonds National de la Recherche
1/05/20 → 31/12/20
Project: Research
Predi-COVID: Luxembourg cohort of positive patients for COVID-19: a stratification study to predict severe prognosis
Fagherazzi, G. (PI), Ollert, M. (CoPI), Berchem, G. (CoPI), Devaux, Y. (Partner), Hübschen, J. (Partner), Schlesser, M. (Partner) & Wilmes, P. (Partner)
FNR - Fonds National de la Recherche
1/04/20 → 31/03/22
Project: Research
CON-VINCE: COvid-19 National survey for assessing Viral spread by Non-affected Carriers
Krüger, R. (PI), Satagopam, V. P. (PI), Huiart, L. (CoPI), Ollert, M. (Partner), Berchem, G. (Partner), Betsou, F. (Partner), Brenner, D. (Partner), Gantenbein, M. (Partner), Vaillant, M. (Partner), Turner, J. (Partner), Aguayo, G. (Partner), Vaillant, M. (Partner), Bahlawane, C. (Partner), Roomp, K. (Partner), Hübschen, J. (Partner) & Snoeck, C. (Partner)
FNR - Fonds National de la Recherche
1/04/20 → 31/12/21
Project: Research
MEGAKINE: Megakines - novel tools for structural insight into receptor:chemokine complexes
Chevigne, A. (PI), Uchanski, T. (CoPI) & Counson, M. (Partner)
FNR - Fonds National de la Recherche
1/03/20 → 28/02/22
Project: Research
ACKR2 (CHEMOKINE RECEPTORS AND IMMUNOTHERAPY): Targeting chemokine receptors: An innovative strategy to reprogram cold to hot tumor microenvironment and to improve PD-1-based cancer immunotherapy
Janji, B. (PI), Chevigne, A. (PI) & Benoit, A. (PhD Student)
Lions Clubs International, FNRS - Fonds National de la Recherche Scientifique
1/03/20 → 28/02/22
Project: Research
ALLON (Action Lions Vaincre le cancer-2019): Impact of the Adaptive Immunity on the Delayed Glioma Progression in a Mouse Model of Allergic Inflammation
Poli, A. (PI) & Ollert, M. (Associated Group Leader)
Action LIONS Vaincre le Cancer
1/01/20 → 31/12/22
Project: Research
INTERceptor: Targeting chemokine receptors for improved cancer immunotherapy
Szpakowska, M. (PI), Chevigne, A. (CoPI) & Janji, B. (Partner)
FNR - Fonds National de la Recherche
1/12/19 → 31/07/20
Project: Research
MICROH-DTU (Anouk Ewen): Microbiomes in One Health
Brenner, D. (PI) & Ewen, A. (PhD Student)
FNR - Fonds National de la Recherche
1/09/19 → 31/08/23
Project: Research
MICROH-DTU (Bianca Brandus): Microbiomes in One Health
Seguin-Devaux, C. (PI) & Brandus, B. (PhD Student)
FNR - Fonds National de la Recherche
1/06/19 → 31/08/24
Project: Research
Muco-IBD: Mucobiomes in the pathogenesis of inflammatory bowel disease
Desai, M. (PI) & Parrish, A. (PhD Student)
FNR - Fonds National de la Recherche
1/05/19 → 30/04/23
Project: Research
PestGutCRC: Effects of pesticides on the gut and their role in cancer development
Appenzeller, B. (PI), Desai, M. (CoPI) & Haan, S. (PI)
1/04/19 → 30/06/22
Project: Research
CoPImmunoPD: Comprehensive peripheral immune status assessment in Parkinson’s disease patients
Hefeng, F. Q. (PI)
Personalised Medicine Consortium (PMC)
15/03/19 → 14/09/21
Project: Research
LIH383: Evaluation of LIH383 as a new neuro-pharmacological modulator
Chevigne, A. (PI), Szpakowska, M. (CoPI) & Langlet, J. (CoPI)
FNR - Fonds National de la Recherche
1/03/19 → 14/11/19
Project: Research
LS-DII 2019: Lecture Series 2019-2021 'Infection & Immunity'
Brenner, D. (PI) & Ollert, M. (CoPI)
FNR - Fonds National de la Recherche
1/02/19 → 14/11/21
Project: Research
MICROH-DTU (Rebecca Czolk): Microbiomes in One Health
Kuehn, A. (PI), Ollert, M. (CoPI) & Czolk, R. (PhD Student)
FNR - Fonds National de la Recherche
1/01/19 → 31/07/23
Project: Research
Characterization and modulation of fish allergenicity towards the production of a low allergen farmed fish
Rodrigues, P. M. (PI), Kuehn, A. (CoPI) & Schrama, D. (PhD Student)
1/01/19 → 31/05/22
Project: Research
MICROH-DTU (Erica Grant): Microbiomes in One Health
Desai, M. (PI) & Grant, E. (PhD Student)
FNR - Fonds National de la Recherche
1/01/19 → 31/12/22
Project: Research
NEXTIMMUNE (Leticia Soriano Baguet): Metabolic gatekeepers in T cells: Decision making and controlling inflammation in vivo
Brenner, D. (CoPI) & Soriano Baguet, L. (PhD Student)
FNR - Fonds National de la Recherche
1/01/19 → 31/12/22
Project: Research
MICROH-DTU (Eleftheria Charalambous): Microbiomes in One Health
Turner, J. (PI) & Charalambous, E. (PhD Student)
FNR - Fonds National de la Recherche
1/01/19 → 31/12/22
Project: Research
MICROH-DTU: Interaction of the lung microbiome with airway epithelial and immune cells
Michel, T. (PI), Hilger, C. (CoPI) & Morel, L. (PhD Student)
FNR - Fonds National de la Recherche
1/01/19 → 31/12/22
Project: Research
IRGal: Targeting Key Factors Involved in Immune Reactions mediated by Tick Bites to the Carbohydrate alpha-Gal
Hilger, C. (PI)
FNR - Fonds National de la Recherche
1/08/18 → 31/12/23
Project: Research