Department of Infection and Immunity

Projects

Projects per year 2010 2017 2018 2019 2020 2021 2022 2023 2029

• 5 Not started
• 45 Active
• 80 Finished

Projects per year

Search results

• Finished

  Antibody-CoV-ID: Development and validation of a SARS-CoV-2 variant surrogate Viral Neutralization Test (sVNT)

  Seguin-Devaux, C.

  European Commission

  8/12/22 → 30/04/23

  Project: Research

• LSMOT2: Lecture series on multi-omics techniques

  Dittmar, G.

  1/12/22 → 30/11/23

  Project: Research

• EAACI-TNFR2: Use of TNFR2 agonist antibody to enhance potent regulatory T cells in allergen-specific immunotherapy

  Bazon, M. & Ollert, M.

  European Academy of Allergy and Clinical Immunology (EAACI)

  1/10/22 → 31/03/23

  Project: Research

• LS-DII 2022: Lecture Series in Infection & Immunity 2022

  Brenner, D. & Ollert, M.

  FNR - Fonds National de la Recherche

  1/01/22 → 31/12/22

  Project: Research

• CSMI: Conseil Supérieur des maladies infectieuses

  Santos Da Silva, E.

  Ministère de la Santé Luxembourg

  1/01/22 → 31/05/23

  Project: Research

  • Publications 100%
  • Publication 100%

• InProFluD: Developing an integrated approach to assess the emergence threat associated with influenza D viruses’ circulating in Europe

  Ducatez, M. F., Snoeck, C., Zohari, S., Saegerman, C., Moreno, A. & Quinnes, E.

  European Food Safety Authority

  10/11/21 → 9/11/23

  Project: Research

  • Virus 100%
  • Threat 100%
  • Influenza 100%
  • Genetics 25%
  • Development 25%

• LSMOT: Next-generation of multi-omics research: going to the single cell

  Dittmar, G.

  FNR - Fonds National de la Recherche

  1/09/21 → 31/08/22

  Project: Research

  • Metabolomics 100%
  • Volume 74%
  • Multi-Omics 74%
  • Cells 74%
  • Tamsulosin 74%

• MEGAKINE: Megakines - novel tools for structural insight into receptor:chemokine complexes

  Uchanski, T. & Chevigne, A.

  European Commission

  1/09/21 → 4/01/22

  Project: Research

  • Chemokine Receptor 100%
  • Chemokine 83%
  • Receptor 66%
  • Protein 50%
  • Ligand 50%

• EXOKINE (ACKR3/CXCR7): Unraveling the role of the ACKR3/CXCR7 receptor in glioblastoma cells survival and invasion in the tumor relapse.

  Rogister, B., Chevigne, A. & Szpakowska, M.

  FNRS - Fonds National de la Recherche Scientifique

  1/07/21 → 30/11/23

  Project: Research

  • Subventricular Zone 100%
  • Chemokine Receptor CXCR7 100%
  • Cell Survival 100%
  • Cell Invasion 100%
  • Cell Migration 25%

• MUCO-IMMUN: MUCOBIOME-MEDIATED IMMUNE PATHWAYS IN INFLAMMATORY BOWEL DISEASES

  Desai, M. & Boudaud, M.

  European Commission

  1/05/21 → 30/04/23

  Project: Research

  • Inflammatory Bowel Disease 100%
  • Mucus 83%
  • Gut Microbiome 66%
  • Patient 50%
  • Food Allergy 50%

• INTERACTINg: Targeting a key promoter of multiple pro-metastatic pathways in breast cancer

  Thomas, C., Dittmar, G. & Berro, F.

  FNRS - Fonds National de la Recherche Scientifique

  1/03/21 → 28/02/23

  Project: Research

  • Cysteine 100%
  • Promoter Region 50%
  • Protein 50%
  • Aptitude 33%
  • Cancer Cell 22%

• Lux-FiCo: From mouse to man: translating findings in mouse study into a human cohort (Luxembourgish Fiber Cohort: Lux-FiCo)

  Desai, M., Bohn, T. & Ollert, M.

  Personalised Medicine Consortium (PMC)

  1/01/21 → 30/06/22

  Project: Research

  • Man 100%
  • Bacterium 100%
  • Mouse Study 100%
  • Translating (Language) 100%
  • Gut 75%

• Prévention transmission covid-19

  Seguin-Devaux, C.

  Ministère de la Santé Luxembourg

  9/10/20 → 31/12/22

  Project: Research

  • Publications 100%

• NanoLux SARS-CoV-2: Assessment of SARS-CoV-2neutralizing antibodies inLuxembourg through novel highlysensitive NanoLuciferase-basedhigh throughput assays

  Chevigne, A. & Ollert, M.

  FNR - Fonds National de la Recherche, Laboratoires Réunis S.A.

  1/09/20 → 14/07/23

  Project: Research

  • Assay 100%
  • SARS Coronavirus 100%
  • Coronavirinae 100%
  • Coronavirus 100%
  • Monitoring 50%

• COV-Array: Coronavirus antigen array for parallelized serological profiling

  Longworth, J. & Dittmar, G.

  FNR - Fonds National de la Recherche

  1/07/20 → 28/02/21

  Project: Research

  • Antigen 100%
  • Coronavirinae 100%
  • Antibodies 100%
  • Antigens 100%
  • Monospecific Antibody 62%

• COMPARE: Comparing the technical performances of three real-time PCRs to counteract the COVID-19 outbreak in Luxembourg

  Seguin-Devaux, C. & Abdelrahman, T.

  FNR - Fonds National de la Recherche

  1/07/20 → 28/02/21

  Project: Research

  • Sample 100%
  • Real Time Polymerase Chain Reaction 100%
  • COVID-19 100%
  • Real-Time Polymerase Chain Reaction 100%
  • Assays 80%

• CovSerum: Early detection of COVID19-induced tissue damage and (hyper)inflammation from serum samples

  Dittmar, G. & Behrmann, I.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • Tissue Injury 100%
  • Protein 66%
  • Serum 50%
  • Inflammation 50%
  • Sample 50%

• NEUTRACOV: A novel high throughput assay to measure plasma NEUTRalizing Activity against SARS-CoV-2 against SARS-CoV-2

  PerezBercoff, D.

  FNR - Fonds National de la Recherche, Rotary Clubs de Luxembourg

  1/06/20 → 30/11/20

  Project: Research

  • Assay 100%
  • Plasma 100%
  • Severe Acute Respiratory Syndrome Coronavirus 2 100%
  • COVID-19 100%
  • Patient 75%

• CORONASTEP+: The value of sewage surveillance to provide new insights on the circulation of SARS-COV-2 and to reveal the true extent of the coronavirus pandemic at the national scale

  Ogorzaly, L., Snoeck, C., Martin-Gallausiaux, C. & Fournier, G.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • Coronavirinae 100%
  • Circulation 100%
  • Prevalence 70%
  • Severe Acute Respiratory Syndrome Coronavirus 2 50%
  • Severe Acute Respiratory Syndrome 50%

• COLIVE*: Role of COmpanion and LIVEstock animals in the epidemiology of SARS-CoV

  Snoeck, C.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • Animals 100%
  • Farm Animal 100%
  • Zoonosis 100%
  • Ferret 100%
  • Cat 100%

• FunBiome: Functional characterization of COVID-19 patient gut microbiome

  Desai, M.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • COVID-19 100%
  • Gut Microbiome 100%
  • Microbiome 100%
  • Severe Acute Respiratory Syndrome Coronavirus 2 50%
  • Gastrointestinal Tract 50%

• COV-Immun: Development of a high performance COVID-19 immunoassay, an essential tool to establish immunity passports in the Luxembourgish population

  Hilger, C.

  FNR - Fonds National de la Recherche

  1/05/20 → 31/12/20

  Project: Research

  • Monitoring 100%
  • Diagnosis 100%
  • Assay 100%
  • Development 100%
  • Screening 100%

• CON-VINCE: COvid-19 National survey for assessing Viral spread by Non-affected Carriers

  Krüger, R., Satagopam, V. P., Huiart, L., Ollert, M., Berchem, G., Betsou, F., Brenner, D., Gantenbein, M., Vaillant, M., Turner, J., Aguayo, G., Vaillant, M., Bahlawane, C., Roomp, K., Hübschen, J. & Snoeck, C.

  FNR - Fonds National de la Recherche

  1/04/20 → 31/12/21

  Project: Research

  • Luxembourg 100%
  • Survey 100%
  • Severe Acute Respiratory Syndrome Coronavirus 2 70%
  • Infection 60%
  • Life 50%

• Predi-COVID: Luxembourg cohort of positive patients for COVID-19: a stratification study to predict severe prognosis

  Fagherazzi, G., Ollert, M., Berchem, G., Devaux, Y., Hübschen, J., Schlesser, M. & Wilmes, P.

  FNR - Fonds National de la Recherche

  1/04/20 → 31/03/22

  Project: Research

  • Voice 100%
  • COVID-19 100%
  • Health 60%
  • Coughing 50%
  • Biological Marker 50%

• MEGAKINE: Megakines - novel tools for structural insight into receptor:chemokine complexes

  Chevigne, A., Uchanski, T. & Counson, M.

  FNR - Fonds National de la Recherche

  1/03/20 → 28/02/22

  Project: Research

  • Chemokine Receptor 100%
  • Chemokine 100%
  • CXCL14 50%
  • CXCR5 6%
  • Chemokine Receptor CXCR5 6%

• ACKR2 (CHEMOKINE RECEPTORS AND IMMUNOTHERAPY): Targeting chemokine receptors: An innovative strategy to reprogram cold to hot tumor microenvironment and to improve PD-1-based cancer immunotherapy

  Janji, B. & Chevigne, A.

  Lions Clubs International, FNRS - Fonds National de la Recherche Scientifique

  1/03/20 → 28/02/22

  Project: Research

  • Chemokine Receptor 100%
  • Cancer Immunotherapy 100%
  • Tumor Microenvironment 100%
  • Immune Checkpoint Blockade 100%
  • Immunocompetent Cell 90%

• ALLON (Action Lions Vaincre le cancer-2019): Impact of the Adaptive Immunity on the Delayed Glioma Progression in a Mouse Model of Allergic Inflammation

  Poli, A. & Ollert, M.

  Action LIONS Vaincre le Cancer

  1/01/20 → 31/12/22

  Project: Research

• INTERceptor: Targeting chemokine receptors for improved cancer immunotherapy

  Szpakowska, M., Chevigne, A. & Janji, B.

  FNR - Fonds National de la Recherche

  1/12/19 → 31/07/20

  Project: Research

  • Neoplasm 100%
  • Chemokine Receptor 100%
  • Malignant Neoplasm 100%
  • Immunotherapy 100%
  • Receptor 50%

• MICROH-DTU (Bianca Brandus): Microbiomes in One Health

  Seguin-Devaux, C. & Brandus, B.

  FNR - Fonds National de la Recherche

  1/06/19 → 31/05/23

  Project: Research

  • One Health 100%
  • Health 50%
  • Microbiome 50%
  • Antibiotic Resistance 33%
  • Environment 25%

• Muco-IBD: Mucobiomes in the pathogenesis of inflammatory bowel disease

  Desai, M. & Parrish, A.

  FNR - Fonds National de la Recherche

  1/05/19 → 30/04/23

  Project: Research

  • Gnotobiotics 100%
  • Gut Microbiome 91%
  • Microbiome 86%
  • Inflammatory Bowel Disease 75%
  • Mucus 73%

• PestGutCRC: Effects of pesticides on the gut and their role in cancer development

  Appenzeller, B., Desai, M. & Haan, S.

  1/04/19 → 30/06/22

  Project: Research

  • Pesticide 100%
  • Malignant Neoplasm 100%
  • Colon Cancer 54%
  • Chronic Disease 18%
  • Microbiome 18%

• LIH383: Evaluation of LIH383 as a new neuro-pharmacological modulator

  Chevigne, A., Langlet, J. & Szpakowska, M.

  FNR - Fonds National de la Recherche

  1/03/19 → 14/11/19

  Project: Research

  • Spectrum 100%
  • Scavenger 100%
  • Chemokine Receptor 100%
  • CXCR7 100%
  • Opioid Peptide 100%

• LS-DII 2019: Lecture Series 2019-2021 'Infection & Immunity'

  Brenner, D. & Ollert, M.

  FNR - Fonds National de la Recherche

  1/02/19 → 14/11/21

  Project: Research

  • Immunity 100%
  • Infection 100%
  • Student 62%
  • Lecture 50%
  • Metabolic Pathway 16%

• MICROH-DTU (Rebecca Czolk): Microbiomes in One Health

  Kuehn, A., Ollert, M. & Czolk, R.

  FNR - Fonds National de la Recherche

  1/01/19 → 31/07/23

  Project: Research

  • Health 100%
  • One Health 100%
  • Microbiome 100%
  • Environment 50%
  • Public Health 50%

• NEXTIMMUNE (Leticia Soriano Baguet): Metabolic gatekeepers in T cells: Decision making and controlling inflammation in vivo

  Brenner, D. & Soriano Baguet, L.

  FNR - Fonds National de la Recherche

  1/01/19 → 31/12/22

  Project: Research

  • Inflammation 100%
  • Decision Making 100%
  • Cells 50%
  • Viral Disease 50%
  • Immunocompetent Cell 50%

• MICROH-DTU (Eleftheria Charalambous): Microbiomes in One Health

  Turner, J. & Charalambous, E.

  FNR - Fonds National de la Recherche

  1/01/19 → 31/12/22

  Project: Research

  • Microbiome 100%
  • Life 75%
  • One Health 50%
  • Health 50%
  • Oral Microbiome 50%

• MICROH-DTU: Interaction of the lung microbiome with airway epithelial and immune cells

  Michel, T., Hilger, C. & Morel, L.

  FNR - Fonds National de la Recherche

  1/01/19 → 31/12/22

  Project: Research

  • Microbiome 100%
  • Immunocompetent Cell 50%
  • Lung 50%
  • One Health 50%
  • Health 50%

• MICROH-DTU (Erica Grant): Microbiomes in One Health

  Desai, M. & Grant, E.

  FNR - Fonds National de la Recherche

  1/01/19 → 31/12/22

  Project: Research

  • Microbiome 100%
  • One Health 78%
  • Gnotobiotics 78%
  • Gut Microbiome 78%
  • Health 78%

• Characterization and modulation of fish allergenicity towards the production of a low allergen farmed fish

  Rodrigues, P. M., Kuehn, A. & Schrama, D.

  1/01/19 → 31/05/22

  Project: Research

  • Farmed Fish 100%
  • Aquaculture 16%
  • Immunoglobulin E 8%
  • Shellfish 8%
  • Tree Nut 8%

• CARES: Casamance Research-program on HIV-Resistance and Sexual health

  Seguin-Devaux, C.

  Fondation Recherche sur le SIDA

  1/07/18 → 31/07/22

  Project: Research

  • Research 100%
  • Patient 100%
  • Viruses 100%

• SIGSING: Spatio-temporal analysis of TGFβ receptor signalling and trafficking studied by peroxidase-mediated quantitative proximity proteomics and correlative imaging

  Dittmar, G., Sandin, S. & Ludwig, A.

  FNR - Fonds National de la Recherche

  15/06/18 → 31/12/20

  Project: Research

  • Peroxidase 100%
  • Endocytosis 100%
  • Proteomics 50%
  • Caveolae 50%
  • Clathrin 50%

• PrISMaHif: Comprehensive analysis of the Hif1α interactome and its regulation by post-translational modifications

  Dittmar, G.

  FNR - Fonds National de la Recherche

  1/06/18 → 30/09/21

  Project: Research

  • Posttranslational Modification 100%
  • Regulatory Mechanism 100%
  • Ubiquitin 97%
  • Cell Function 77%
  • Protein Sequencing 77%

• PLAN: Plan national de lutte contre le VIH/SIDA et les IST

  Seguin-Devaux, C.

  Ministère de la Santé Luxembourg

  1/06/18 → 31/12/18

  Project: Research

  • France 100%
  • Mobilization 75%
  • Gastric Inhibitory Polypeptide 50%
  • Infection 50%
  • Sons 50%

• EFSA Partnering Grant: Risk assessment for influenza D in Europe

  Ducatez, M. F., Verheije, H., Snoeck, C., Zohari, S., Saegerman, C. & Foni, E.

  European Food Safety Authority

  21/02/18 → 20/02/20

  Project: Research

  • Influenza 100%
  • Virus 40%
  • Cattle 24%
  • Viruses 20%
  • Risk Assessment 20%

• UDI: Real-time molecular surveillance to prioritize HCV treatment in injecting drug users

  Seguin-Devaux, C.

  1/02/18 → 31/12/22

  Project: Research

  • Phylogeny 100%
  • Reinfection 100%
  • Drug 100%
  • Time 66%
  • Social Network 50%

• MADAM: MAternal Diabetes and neuropsychiAtric vulnerability in offspring: role of DNAmethylation

  Turner, J., Darnaudery, M. & Movassat, J.

  FNR - Fonds National de la Recherche

  1/01/18 → 30/04/22

  Project: Research

  • Life 100%
  • Progeny 90%
  • Maternal Diabetes Mellitus 90%
  • Child 90%
  • Epigenomics 78%

• LS-DII 2018: Lecture Series 2018 'Infection & Immunity'

  Brenner, D. & Ollert, M.

  FNR - Fonds National de la Recherche

  1/01/18 → 31/01/19

  Project: Research

  • Immunity 100%
  • Infection 100%
  • Luxembourg 100%
  • Scientists 100%
  • Health 85%

• APSIS: Allergen Peptide SIgnatureS in allergic vs tolerant individuals (APSIS): paving the way for novel personalized medicine approaches to diagnose and cure food allergies

  Kuehn, A., Schneider, R. & Ammerlaan, W.

  Personalised Medicine Consortium (PMC)

  1/01/18 → 30/11/20

  Project: Research

  • Peptide 100%
  • Allergen 100%
  • Food Allergy 100%
  • Diagnosis 50%
  • Personalized Medicine 50%

• CoMiX: Therapeutic and Safety Evaluation of the CoMiX immunoconjugates as a novel complement activation-based immunotherapy strategy

  Seguin-Devaux, C.

  FNR - Fonds National de la Recherche

  1/01/18 → 31/12/19

  Project: Research

  • Neoplasm 100%
  • Polymer 100%
  • Antibody Conjugate 100%
  • Immunotherapy 100%
  • Complement Activation 100%

• GOODSYN: Immunodeficiency with autoimmunity: unravelling the molecular origin of Good’s syndrome

  Zimmer, J., Ollert, M. & Schneider, J.

  FNR - Fonds National de la Recherche

  1/01/18 → 31/12/20

  Project: Research

  • Immunodeficiency 100%
  • Syndrome 100%
  • Immune Deficiency 100%
  • Common Variable Immunodeficiency 55%
  • Autoimmunity 50%