Department of Infection and Immunity

Projects

Projects per year 2010 2017 2018 2019 2020 2021 2026

• 15 Not started
• 23 Active
• 62 Finished

Projects per year

Search results

• Active

  EVceptor: Role of chemokine receptor-bearing extracellular vesicles in leukaemia and lymphoma

  Chevigne, A., Paggetti, J. & Szpakowska, M.

  FNRS - Fonds National de la Recherche Scientifique

  1/05/22 → 30/04/24

  Project: Research

  • Extracellular Vesicles 100%
  • Chemokine Receptors 95%
  • Lymphoma 70%
  • Leukemia 69%
  • Chemokine CXCL12 54%

• TARGETPATHO: SPATIAL TARGETED PROTEOMICS USING PASEF-PRM

  Dittmar, G.

  1/04/22 → 30/04/25

  Project: Research

  • proteomics 100%
  • proteins 50%
  • ionization 42%
  • spectrometers 41%
  • prototypes 37%

• I2TRON Naphisabet Wanniang: Markers of shaping and educating the early life immune response to food proteins

  Kuehn, A.

  FNR - Fonds National de la Recherche

  1/04/22 → 31/03/26

  Project: Research

• HifReg: Hif-α non-canonical regulation by PTMs and new interaction partners

  Dittmar, G., Letellier, E. & Krauß, S.

  FNR - Fonds National de la Recherche, Fondation Cancer

  1/03/22 → 28/02/25

  Project: Research

  • Ubiquitin 100%
  • Deubiquitinating Enzymes 46%
  • mesoglycan 43%
  • Ubiquitin-Protein Ligases 18%
  • Oxidative Phosphorylation 18%

• VIRALERT: Environmental-based epidemiology for preparedness and early detection of viral epidemics

  Ogorzaly, L. & Snoeck, C.

  FNR - Fonds National de la Recherche

  2/01/22 → 31/12/24

  Project: Research

  • Epidemics 100%
  • SARS Virus 60%
  • Pandemics 58%
  • Epidemiology 55%
  • Viruses 54%

• InProFluD: Developing an integrated approach to assess the emergence threat associated with influenza D viruses’ circulating in Europe

  Ducatez, M. F., Snoeck, C., Zohari, S., Saegerman, C., Moreno, A. & Quinnes, E.

  European Food Safety Authority

  10/11/21 → 9/11/23

  Project: Research

  • Thogotovirus 100%
  • Farms 15%
  • Human Influenza 12%

• I2TRON Camille Rolin: i2TRON: PRE-CLINICAL EVALUATION OF IMMUNOCONJUGATES ACTIVATING NK CELLS IN DIFFERENT CANCER MODELS

  Seguin-Devaux, C. & Rolin, C.

  FNR - Fonds National de la Recherche

  1/09/21 → 31/08/25

  Project: Research

• ImmunoTwin: LONG TERM IMMUNOLOGICAL CONSEQUENCES IN ADVERSITY-DIVERGENT TWINS

  Turner, J., D’Ambrosio, C., Vögele, C. & Diewald, M.

  FNR - Fonds National de la Recherche

  1/09/21 → 30/09/25

  Project: Research

  • health 100%
  • acute care 74%
  • economist 53%
  • Social Environment 51%
  • expenditures 48%

• EXOKINE (ACKR3/CXCR7): Unraveling the role of the ACKR3/CXCR7 receptor in glioblastoma cells survival and invasion in the tumor relapse.

  Rogister, B., Chevigne, A. & Szpakowska, M.

  FNRS - Fonds National de la Recherche Scientifique

  1/07/21 → 30/11/23

  Project: Research

  • Glioblastoma 100%
  • Cell Survival 77%
  • Lateral Ventricles 63%
  • Recurrence 58%
  • Neoplasms 32%

• ACKR3/CXCL12 axis in GBM: Study of the CXCL12-CXCR4/ACKR3 signaling in glioblastoma and of its importance in the control of translation and relapses

  Chevigne, A. & Rogister, B.

  FNR - Fonds National de la Recherche

  3/05/21 → 30/05/25

  Project: Research

  • Chemokine Receptors 100%
  • Scavenger Receptors 71%
  • Glioblastoma 48%
  • Adrenomedullin 37%
  • CC Chemokines 34%

• MUCO-IMMUN: MUCOBIOME-MEDIATED IMMUNE PATHWAYS IN INFLAMMATORY BOWEL DISEASES

  Desai, M. & Boudaud, M.

  European Commission

  1/05/21 → 30/04/23

  Project: Research

  • Food Hypersensitivity 100%
  • Mucus 90%
  • Gastrointestinal Microbiome 83%
  • gastric mucus glycoproteins 70%
  • Microbiota 63%

• INTERACTINg: Targeting a key promoter of multiple pro-metastatic pathways in breast cancer

  Thomas, C., Dittmar, G. & Berro, F.

  FNRS - Fonds National de la Recherche Scientifique

  1/03/21 → 28/02/23

  Project: Research

  • Cysteine 100%
  • Podosomes 70%
  • Breast Neoplasms 67%
  • Proteins 47%
  • Aptitude 24%

• I2TRON Rafael Luis: Development of chemokine receptor modulators for improved cancer immunotherapy

  Chevigne, A. & Luis, R.

  FNR - Fonds National de la Recherche

  1/03/21 → 28/02/25

  Project: Research

• I2TRON Agnieszka Demczuk: Modulation of cytokine pathways for allergy specific immunotherapy

  Ollert, M. & Demczuk, A.

  FNR - Fonds National de la Recherche

  1/02/21 → 31/01/25

  Project: Research

• CYTOMARK: Development of a personalised non-invasive diagnosis of endometrial cancer

  Dittmar, G., Colas, E., Casares de Cal, M. D. L. A., Tover, A., Gultekin, M. & Kilic, Y.

  FNR - Fonds National de la Recherche

  1/02/21 → 31/01/25

  Project: Research

  • Endometrial Neoplasms 100%
  • Spain 63%
  • Turkey 46%
  • Biomarkers 42%
  • Luxembourg 35%

• ALAC: Age Acceleration and the Life Course

  D’Ambrosio, C. & Turner, J.

  FNR - Fonds National de la Recherche

  1/09/20 → 30/09/24

  Project: Research

  • socioeconomic factors 100%
  • health 64%
  • public budget 63%
  • economic sociology 59%
  • public finance 59%

• NanoLux SARS-CoV-2: Assessment of SARS-CoV-2neutralizing antibodies inLuxembourg through novel highlysensitive NanoLuciferase-basedhigh throughput assays

  Chevigne, A. & Ollert, M.

  FNR - Fonds National de la Recherche, Laboratoires Réunis S.A.

  1/09/20 → 14/07/23

  Project: Research

  • SARS Virus 100%
  • Luxembourg 90%
  • Coronavirus 71%
  • Neutralizing Antibodies 56%
  • Severe Acute Respiratory Syndrome 36%

• Opiokine: Multidimensional regulation of the opioid network by ACKR3

  Palmer, C., Chevigne, A. & Szpakowska, M.

  FNR - Fonds National de la Recherche

  13/07/20 → 14/07/23

  Project: Research

  • Opioid Receptors 100%
  • Opioid Analgesics 78%
  • Opioid Peptides 74%
  • Scavenger Receptors 55%
  • Chemokine Receptors 44%

• SMART GLIOBLASTOMA: SMART GLIOBLASTOMA: Signaling and Modulation of the AtypicalIsoform of the CXCR3 RecepTor in glioblastoma cells

  Chevigne, A., Niclou, S., Rogister, B., Hanson, J. & D'Uonnolo, G.

  FNRS - Fonds National de la Recherche Scientifique

  15/05/20 → 14/10/24

  Project: Research

  • CXCR3 Receptors 100%
  • Glioblastoma 79%
  • Protein Isoforms 50%
  • Chemokine Receptors 19%
  • Brain Neoplasms 16%

• METGLIO: eEF1A1K165 methylation modulator of protein synthesis and promoter of glioma tumorigenesis

  Dittmar, G. & Niclou, S.

  FNRS - Fonds National de la Recherche Scientifique

  1/01/20 → 14/06/23

  Project: Research

  • Glioma 100%
  • Methylation 97%
  • alpha-hydroxyglutarate 91%
  • Isocitrate Dehydrogenase 63%
  • Epigenome 46%

• MICROH-DTU (Bianca Brandus): Microbiomes in One Health

  Seguin-Devaux, C. & Brandus, B.

  FNR - Fonds National de la Recherche

  1/06/19 → 31/05/23

  Project: Research

  • microbiome 100%
  • chronic diseases 44%
  • microbiology 41%
  • antibiotic resistance 36%
  • human health 34%

• Muco-IBD: Mucobiomes in the pathogenesis of inflammatory bowel disease

  Desai, M., Martens, E. C., Sofos, S., Hansson, G. & Parrish, A.

  FNR - Fonds National de la Recherche

  1/05/19 → 30/04/23

  Project: Research

  • Gastrointestinal Microbiome 100%
  • Microbiota 92%
  • Germ-Free Life 65%
  • Dietary Fiber 56%
  • Mucus 51%

• NEXTIMMUNE (Program management): NEXT GENERATION IMMUNOSCIENCE: Advanced Concepts for Deciphering Acute and Chronic Inflammation

  Ollert, M.

  FNR - Fonds National de la Recherche

  1/01/17 → 30/09/23

  Project: Research

  • immunology 100%
  • human diseases 86%
  • inflammation 85%
  • Th17 Cells 63%
  • Citric Acid 58%
• Not started

  EPICON: Epigenetic control of effector lymphocyte function

  SCHEER, S. & Turner, J.

  1/04/23 → 31/05/26

  Project: Research

• ROSETTA: A global registry on second generation and long-acting integrase inhibitor failures.

  Seguin-Devaux, C.

  Gilead Sciences, Inc.

  Project: Research

• Antibody-CoV-ID: Development and validation of a SARS-CoV-2 variant surrogate Viral Neutralization Test (sVNT)

  Seguin-Devaux, C.

  European Commission

  Project: Research

• CAROFIBER: Interactions of carotenoids and dietary fiber – implications for bioavailability and colonic degradation

  Bohn, T. & Desai, M.

  Project: Research

• PSEUDO: Pre-clinical validation of CoMiX and Bikes/Trikes against infections with Pseudomonas aeruginosa

  Seguin-Devaux, C., Zimmer, J. & Si-Tahar, M.

  Project: Research

• B-MARK: MICROBIOME-BASED BIOMARKERS AS PERSONALISED RISK FACTORS OF DISEASE

  Desai, M.

  Project: Research

• Nextimmune-2 (Program Management): The Next Generation Immunoscience

  Brenner, D. & Ollert, M.

  Project: Research

  • disease models 100%
  • data analysis 68%
  • immunology 45%
  • communication (human) 40%
  • education 37%

• Conolidine (TLV-2022-PDR): Regulation of glioblastoma growth and tumor microenvironment by receptors ACKR3 and CXCR4

  Szpakowska, M. & Chevigne, A.

  Project: Research

  • CXCR4 Receptors 100%
  • Tumor Microenvironment 75%
  • Glioblastoma 71%
  • conolidine 43%
  • Growth 36%

• HOPE-IOID: Multilevel regulation and modulation of the new opioid peptide scavenger ACKR3

  Chevigne, A.

  Project: Research

• LSMOT2: Lecture series on multi-omics techniques

  Dittmar, G.

  Project: Research

• I2TRON (NN): Impact of gut microbiome on cancer immunotherapy

  Desai, M. & Craig, S.

  FNR - Fonds National de la Recherche

  Project: Research

• CHAMP: The effects of childhood adversity on mental health and learning: A nationwide longitudinal project with children in alternative care in Luxembourg

  Turner, J.

  FNR - Fonds National de la Recherche

  Project: Research

• ALLPRET: Allergenicity prediction toolbox for novel foods

  Kuehn, A. & Hilger, C.

  Project: Research

  • novel foods 100%
  • allergenicity 97%
  • legume protein 48%
  • prediction 43%
  • food allergies 42%

• LS-DII 2023: Lecture Series in Infection & Immunity 2023

  Brenner, D. & Ollert, M.

  Project: Research

• HealthyW8: EMPOWERING HEALTHY LIFESTYLE BEHAVIOUR THROUGH PERSONALIZED INTERVENTION PORTFOLIOS TO PREVENT AND CONTROL OBESITY DURING VULNERABLE STAGES OF LIFE

  Bohn, T., Vahid, F., Desai, M., Turner, J., Devaux, Y. & Malisoux, L.

  Project: Research

• Finished

  CSMI: Conseil Supérieur des maladies infectieuses

  Santos Da Silva, E.

  Ministère de la Santé Luxembourg

  1/01/22 → 31/12/22

  Project: Research

• MEGAKINE: Megakines - novel tools for structural insight into receptor:chemokine complexes

  Uchanski, T. & Chevigne, A.

  European Commission

  1/09/21 → 4/01/22

  Project: Research

  • Chemokine Receptors 100%
  • Chemokines 51%
  • Ligands 29%
  • Molecular Structure 16%
  • Physiological Phenomena 14%

• LSMOT: Next-generation of multi-omics research: going to the single cell

  Dittmar, G.

  FNR - Fonds National de la Recherche

  1/09/21 → 31/08/22

  Project: Research

  • Metabolomics 100%
  • Proteomics 87%
  • Proteins 59%
  • Biological systems 37%
  • Data integration 37%

• Lux-FiCo: From mouse to man: translating findings in mouse study into a human cohort (Luxembourgish Fiber Cohort: Lux-FiCo)

  Desai, M., Bohn, T., Ollert, M. & Beaufort, C. D.

  Personalised Medicine Consortium (PMC)

  1/01/21 → 30/06/22

  Project: Research

  • dietary fiber 100%
  • bacteria 45%
  • intestinal microorganisms 45%
  • low fiber diet 36%
  • diet 32%

• COMPARE: Comparing the technical performances of three real-time PCRs to counteract the COVID-19 outbreak in Luxembourg

  Seguin-Devaux, C. & Abdelrahman, T.

  FNR - Fonds National de la Recherche

  1/07/20 → 28/02/21

  Project: Research

  • Luxembourg 100%
  • Real-Time Polymerase Chain Reaction 49%
  • Disease Outbreaks 41%
  • RNA 23%
  • SARS Virus 16%

• COV-Array: Coronavirus antigen array for parallelized serological profiling

  Longworth, J. & Dittmar, G.

  FNR - Fonds National de la Recherche

  1/07/20 → 28/02/21

  Project: Research

  • Coronavirinae 100%
  • antigens 75%
  • antibodies 62%
  • antibody formation 26%
  • immunoglobulins 26%

• FunBiome: Functional characterization of COVID-19 patient gut microbiome

  Desai, M.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • Gastrointestinal Microbiome 100%
  • SARS Virus 83%
  • Disease Susceptibility 63%
  • Microbiota 56%
  • Gastrointestinal Tract 49%

• COLIVE*: Role of COmpanion and LIVEstock animals in the epidemiology of SARS-CoV

  Snoeck, C.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • SARS Virus 100%
  • Livestock 59%
  • Zoonoses 45%
  • Pets 44%
  • Viruses 35%

• NEUTRACOV: A novel high throughput assay to measure plasma NEUTRalizing Activity against SARS-CoV-2 against SARS-CoV-2

  PerezBercoff, D.

  FNR - Fonds National de la Recherche

  1/06/20 → 30/11/20

  Project: Research

  • SARS Virus 100%
  • Luxembourg 54%
  • Plasmapheresis 41%
  • Coronavirus 28%
  • Vaccines 25%

• CORONASTEP+: The value of sewage surveillance to provide new insights on the circulation of SARS-COV-2 and to reveal the true extent of the coronavirus pandemic at the national scale

  Ogorzaly, L., Snoeck, C., Martin-Gallausiaux, C. & Fournier, G.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • severe acute respiratory syndrome 100%
  • Sewage 83%
  • Coronavirus 82%
  • Pandemics 69%
  • Waste Water 63%

• CovSerum: Early detection of COVID19-induced tissue damage and (hyper)inflammation from serum samples

  Dittmar, G. & Behrmann, I.

  FNR - Fonds National de la Recherche

  1/06/20 → 31/03/21

  Project: Research

  • Viruses 100%
  • Proteins 82%
  • Cytokines 69%
  • Blood Proteins 66%
  • Inflammation 66%

• COV-Immun: Development of a high performance COVID-19 immunoassay, an essential tool to establish immunity passports in the Luxembourgish population

  Hilger, C.

  FNR - Fonds National de la Recherche

  1/05/20 → 31/12/20

  Project: Research

  • Luxembourg 100%
  • Immunologic Monitoring 80%
  • Viral Proteins 66%
  • Immunoassay 62%
  • Recombinant Proteins 61%