Department of Cancer Research

1/01/22 → 31/12/22

Project: Research

DynCell: Dynamics modelling from single-cell data

Aalto, A.

FNR - Fonds National de la Recherche, Sprint Bioscience

1/12/21 → 30/11/22

Project: Research

SMART COMBO: Improving cancer immunotherapy based on anti-PD-1 and STING agonists by combining small innovative molecule

Janji, B., De Milito, A. & Murera, D.

15/07/21 → 14/07/23

Project: Research

INTERACTINg: Targeting a key promoter of multiple pro-metastatic pathways in breast cancer

Thomas, C., Dittmar, G. & Berro, F.

1/03/21 → 28/02/23

Project: Research

EMT-TNBC: EMT-dependent regulation of the ectonucleotidase CD73 in Triple Negative Breast Cancer and its role as a new therapeutic target

15/02/21 → 14/02/23

Project: Research

EV-META-L (EV METAbolism in Leukemia): Involvement of leukemic-derived extracellular vesicles in tumor microenvironment metabolic rewiring

Paggetti, J., Meiser, J. & Moussay, E.

Personalised Medicine Consortium (PMC)

1/02/21 → 30/06/23

Project: Research

PIMP-GBM: Prognostic Impact of Monocyte subsets in Patients with Glioblastoma

Michelucci, A., Skupin, A. & Betsou, F.

1/01/21 → 31/12/22

Project: Research

INCOM (RCMS-2020): Identification of new common predictive biomarkers to stratify TNBC breast cancer patients for treatment with emerging immune checkpoints

Fondation Recherche Cancer et Sang

15/10/20 → 1/01/22

Project: Research

CAMeSyn: Contribution of Astrocyte Metabolism to Synucleinopathy in Parkinson’s disease.

Meiser, J. & Grünewald, A.

1/09/20 → 31/08/23

Project: Research

CIAO-COVID 19 (2nd batch): Comparative antiviral efficacy of different autophagy inhibitors against COVID-19

Noman, M. Z. & Janji, B.

Lions Clubs International, FNRS - Fonds National de la Recherche Scientifique

1/07/20 → 28/02/21

Project: Research

ACKR2 (CHEMOKINE RECEPTORS AND IMMUNOTHERAPY): Targeting chemokine receptors: An innovative strategy to reprogram cold to hot tumor microenvironment and to improve PD-1-based cancer immunotherapy

Janji, B. & Chevigne, A.

1/03/20 → 28/02/22

Project: Research

EPITRANS: Impact of IDH1 mutation on Epitranscriptome regulation in Gliomas

Fritah, S. & Niclou, S.

1/01/20 → 31/12/21

Project: Research

DANTE: Harnessing DNA repair factors to promote an innate immune response against glioblastoma: an invitro RNAi screen selecting phagocytosis promoting genes in glioblastoma cells

Van Dyck, E., Michelucci, A., Nazarov, P., Skupin, A. & Mittelbronn, M.

Fondation de Luxembourg

1/01/20 → 31/12/21

Project: Research

CRP2-TME: CRP2, an innovative target for metastatic breast cancer, with multiple rolesin the tumour and tumour microenvironmen

Thomas, C. & Berchem, G.

Lions Clubs International

1/01/20 → 31/12/21

Project: Research

SHIFT: Shifting immune-suppressed monocyte-derived macrophage programs into microglia-like reactive cells in Glioblastoma

Michelucci, A.

1/01/20 → 31/12/22

Project: Research

ALLON (Action Lions Vaincre le cancer-2019): Impact of the Adaptive Immunity on the Delayed Glioma Progression in a Mouse Model of Allergic Inflammation

Poli, A. & Ollert, M.

Action LIONS Vaincre le Cancer

1/01/20 → 31/12/22

Project: Research

COMBO KD II (Action Lions Vaincre le cancer-2019): Improving the efficacy of renal cell carcinoma immunotherapy by combining anti-PD-1 and anti-CD47 immune checkpoints

Action LIONS Vaincre le Cancer

1/01/20 → 30/06/22

Project: Research

PAELLA: A NOVEL PERSONALIZED STRATEGY TARGETING DNA REPAIR PATHWAY ADDICTIONS IN GLIOBLASTOMA: FROM PATIENT STRATIFICATION TO PRECLINICAL VALIDATION

Van Dyck, E.

Lions Clubs International

1/01/20 → 31/12/21

Project: Research

INTERceptor: Targeting chemokine receptors for improved cancer immunotherapy

Szpakowska, M., Chevigne, A. & Janji, B.

1/12/19 → 31/07/20

Project: Research

CLL-EV impact on immune cells: Impact of Chronic Lymphocytic Leukemia-derived extracellular vesicles onthe microenvironment immune landscape

Paggetti, J., Stamatopoulos, B. & Moussay, E.

1/10/19 → 30/09/21

Project: Research

Anti-glycation drugs as immunotherapy

1/10/19 → 30/09/22

Project: Research

H-1PV/ABT-737 combination against glioma: Development of a novel combination therapy based on oncolytic parvovirus H-1PV and the BH3 mimetic ABT-737 against glioblastoma

Marchini, A.

1/10/19 → 30/09/20

Project: Research

Modulators of chemoresistance in GBM: DNA repair mechanisms as molecular determinants of glioblastomachemoresistance: in vitro investigation and characterization of novel animalmodels

Van Dyck, E. & Niclou, S.

Fondatioun Kriibskrank Kanner

1/10/19 → 30/09/21

Project: Research

NEUROIMMUNOTHERAPY PHASE II: Combining JQI and PD-1 as an innovative approach for the treatment of Childhood Neuroblastoma.

Janji, B. & Berchem, G.

1/07/19 → 30/06/23

Project: Research

ParvoAct1: Development of novel oncolytic Paroviruses with ability to silence the TRAF3IP2 Gene as novel therapeutics against Glioblastoma

Marchini, A. & Niclou, S.

Alliance of Cardiovascular Researchers

1/05/19 → 30/04/21

Project: Research

AUTOKIR: Combining selective pharmacological inhibitors of autophagy with NK immune checkpoint blockade anti-KIR: An innovative approach to improve NK-based cancer immunotherapy

Janji, B. & Berchem, G.

Lions Clubs International

1/03/19 → 28/02/21

Project: Research

Anti-PD-1 and anti-CD47 combination: CD47 and PD-1 blockade: a new cutting edge COMBI approach to simultaneously stimulate macrophages and re-activate T cell-mediated destruction of highly aggressive metastatic breast tumors

Janji, B. & Berchem, G.

FNRS - Fonds National de la Recherche Scientifique, Fondation Cancer

15/02/19 → 30/04/21

Project: Research

CANBIO (Hugo Dosquet): Development of methodologies for monitoring cancer progression and predicting treatment response

Azuaje, F. & Dosquet, H.

1/01/19 → 31/12/22

Project: Research

COMBATIC 2018: Improving T-cell and Macrophage Immune checkpoint blockades by combining autophagy inhibitors

1/01/19 → 31/07/23

Project: Research

RESCOM-2018: 4th Lecture Series in Cancer Research

Niclou, S., Bjerkvig, R. & Behrmann, I.

15/11/18 → 14/11/21

Project: Other

GBModImm: Innovative Models and Oncolytic Viruses for Immunotherapy of Glioblastoma

Niclou, S., Marchini, A., Bours, V., Robe, P. & Salvato, I.

1/11/18 → 31/01/23

Project: Research

Treg LLC : Role of regulatory T cells in the development and progression of chroniclymphocytic leukemia

Moussay, E., Paggetti, J., Berchem, G. & Pagano, G.

1/10/18 → 30/09/22

Project: Research

1cFlux: Understanding and targeting the function of formate overflow in cancer cells

Meiser, J.

1/09/18 → 31/08/23

Project: Research

FUSGLIO: MRgFUS facilitated local treatment of brain tumors

Keunen, O.

1/08/18 → 31/07/19

Project: Research

Reverting Cancer Driver Mutations in Gliomas

Fritah, S.

1/07/18 → 30/06/19

Project: Research

PFP: Personal Functional Profiling

Kwon, Y., Mao, X. & Michel, T.

23/04/18 → 22/04/21

Project: Research

CANBIO (Yue Zhang): Development of methodologies for monitoring cancer progression and predicting treatment response

Nazarov, P. & Zhang, Y.

1/02/18 → 31/01/22

Project: Research

Think Pink II: The Student Training Project

Thomas, C.

Think Pink Luxembourg

1/01/18 → 31/12/19

Project: Other

DEMICS: Decomposition of mixed transcriptomes for classification of heterogeneous tumour samples

Nazarov, P.

1/01/18 → 31/01/21

Project: Research

ASTROSYS: Systems analysis of astrocytes differentiation under inflammatory conditions

Michelucci, A. & Grandbarbe, L.

1/01/18 → 30/12/21

Project: Research

CANBIO (Carina Fabian): Targeting the glycolytic metabolism induced by anti-angiogenic treatment in Glioblastoma

Niclou, S. & Fabian, C.

15/11/17 → 14/11/21

Project: Research

CANBIO (Lia Pinto): Targeting DNA repair mechanisms in primary glioblastoma and their recurrences: from basic mechanisms to pre-clinical aspects and personalized therapy

Van Dyck, E. & Pinto, L.

1/11/17 → 31/10/21

Project: Research

CANBIO (Ernesto Gargiulo): Exosome proteins and RNA as biomarkers of prostate cancer progression and metastasis

Janji, B. & Gargiulo, E.

1/10/17 → 30/09/21

Project: Research

TETHER: Targeted Epigenetic Therapy for Relapsed Glioblastoma

Niclou, S.

1/10/17 → 30/11/20

Project: Research

Hypoxia 2017: Impact of the modulation of the intratumoral hypoxia on the improvement ofPD-1/PD-L1-based immune checkpoint blockade

Janji, B., Gallez, B., Berchem, G. & Haan, S.

1/10/17 → 30/09/20

Project: Research

Pinpointing Glioblastoma Phospho-Sites: MS-based proteomic approach to characterize phosphosignaling in glioblastoma

Dittmar, G. & Niclou, S.

1/10/17 → 30/09/19

Project: Research

PHB+eIF4LLC: Inhibition of prohibitins and translation in chronic lymphocytic leukemi

Moussay, E., Paggetti, J. & Berchem, G.

1/10/17 → 31/01/22

Project: Research

CANBIO (Malina Xiao): Role of hypoxia in the establishment of an immune suppressive tumour microenvironment

Janji, B. & Xiao, M.

15/09/17 → 14/09/21

Project: Research

METASTALIM: Inhibition of breast cancer metastasis by targeting critical cytoskeletal components of invadopodia

Thomas, C. & Mao, X.