Department of Cancer Research

Collaboration Fondation Cancer - FNR

1/09/22 → 30/08/26

Project: Research

1cFlex: Understanding the Flexibility of 1C metabolism and its role during metastatic dissemination of cancer cell

Meiser, J. & Letellier, E.

1/09/22 → 30/09/26

Project: Research

Synapodia: Novel synaptic filopodium-like protrusions (SFPs) protect tumor cells against cytotoxic lymphocyte-mediated killing

Thomas, C. & Filali, L.

FNR - Fonds National de la Recherche, Fondation Cancer

15/07/22 → 14/08/25

Project: Research

DIOMEDES: Deconvolution of heterogeneity in the Glioblastoma cellular ecosystem for understanding treatment resistance and improving patient stratification

Golebiewska, A., Nazarov, P., Mittelbronn, M., Skupin, A., Zinovyev, A., Bjerkvig, R. & Brown, D.

FNR - Fonds National de la Recherche, Fondation Cancer

1/07/22 → 30/06/25

Project: Research

EVceptor: Role of chemokine receptor-bearing extracellular vesicles in leukaemia and lymphoma

Chevigne, A., Paggetti, J. & Szpakowska, M.

1/05/22 → 30/04/24

Project: Research

INCITE: Investigating the role of CMTM proteins in the regulation of PD-L1 expression

1/04/22 → 30/08/24

Project: Research

C2I: CHECKPOINT INHIBITORS IMPROVEMENT FOR THE TREATMENT OF CANCER

1/04/22 → 31/10/25

Project: Research

RESCOM-2021: 5th Lecture Series in Cancer Research

Niclou, S.

3/01/22 → 31/12/24

Project: Research

CancerProfile: Predictive and personalized medicine of pancreatic cancer

Mittelbronn, M.

1/01/22 → 30/01/26

Project: Research

TRICK-ALDH: Assessment the impact of selective ALDH1 inhibitors on tumor infiltrating lymphocytes and the therapeutic benefit of Immune checkpoint blockers

Berchem, G. & Janji, B.

1/01/22 → 31/07/25

Project: Research

NCTCR: National Centre of Translational Cancer Research

Niclou, S. & Berchem, G.

1/01/22 → 31/12/22

Project: Research

SUNRISE (TLV-PDR-2021): TARGETING TUMOR PROPAGATING CELLS IN GLIOBLASTOMA: FROM MECHANISTICINSIGHTS TO PRECISION MEDICINE

Van Dyck, E., Rogister, B., Neirinckx, V., Nazarov, P. & Herold‐mende, C.

1/12/21 → 30/04/24

Project: Research

IMPACT 21: IMPROVING CANCER IMMUNOTHERAPY BY TARGETING HYPOXIA

Janji, B. & Benoit, A.

1/11/21 → 29/03/24

Project: Research

I2TRON Kim Eiden: The role of mitochondrial folate metabolism during macrophage polarization (Mac1L)

Meiser, J. & Eiden, K.

15/10/21 → 14/10/25

Project: Research

SMART COMBO: Improving cancer immunotherapy based on anti-PD-1 and STING agonists by combining small innovative molecule

Janji, B. & De Milito, A.

FNR - Fonds National de la Recherche, Lions Clubs International

15/07/21 → 14/07/23

Project: Research

TERMINI: Roles of NEIL3 DNA glycosylase in telomere dynamics and DNA demethylation in glioblastoma: From molecular insights topreclinical target validation

Van Dyck, E., Sinkkonen, L. & Baidarjad, H.

1/07/21 → 30/06/23

Project: Research

GLASS-LUX: Glioma Longitudinal AnalySiS in Luxembourg (GLASS-LUX): ex vivo and in vivo Functional Profiling of Recurrent Gliomas

Niclou, S., Golebiewska, A., Kwon, Y., Nazarov, P. & Klink, B.

Collaboration Fondation Cancer - FNR , FNR - Fonds National de la Recherche

1/06/21 → 31/12/25

Project: Research

ImmoGBM: ImmoGBM

Niclou, S., Robe, P., Bours, V., Rezaeipour, M. & Golebiewska, A.

1/06/21 → 31/05/23

Project: Research

I2TRON Elena Ockfen: Biological and clinical implications of PD-L1 protein polarization at the tumor tissue and cell levels

Thomas, C. & Ockfen, E.

1/03/21 → 28/02/25

Project: Research

INTERACTINg: Targeting a key promoter of multiple pro-metastatic pathways in breast cancer

Thomas, C., Dittmar, G. & Berro, F.

1/03/21 → 28/02/23

Project: Research

I2TRON Frida Lind-Holm Mogensen: Microglia programs under PARK7/DJ-1 deficiency, a genetic cause of Parkinson’s disease

Michelucci, A. & Lind-Holm, F.

15/02/21 → 14/02/25

Project: Research

EMT-TNBC: EMT-dependent regulation of the ectonucleotidase CD73 in Triple Negative Breast Cancer and its role as a new therapeutic target

15/02/21 → 14/02/23

Project: Research

EV-META-L (EV METAbolism in Leukemia): Involvement of leukemic-derived extracellular vesicles in tumor microenvironment metabolic rewiring

Paggetti, J., Meiser, J. & Moussay, E.

1/02/21 → 30/06/23

Project: Research

I2TRON Pilar Moreno : Precision medicine for Glioblastoma patients: a patient-based pre-clinical platform for immuno-oncology

Niclou, S., Golebiewska, A. & Moreno Sanchez, P. M.

Personalised Medicine Consortium (PMC)

1/02/21 → 31/01/25

Project: Research

PIMP-GBM: Prognostic Impact of Monocyte subsets in Patients with Glioblastoma

Michelucci, A., Skupin, A. & Betsou, F.

1/01/21 → 31/12/22

Project: Research

TRANSACTINg: Unraveling the genetic pathways underlying actin remodeling-mediated cancer immune evasion

Thomas, C., Skupin, A. & Krecke, M.

1/01/21 → 31/12/22

Project: Research

CAMeSyn: Contribution of Astrocyte Metabolism to Synucleinopathy in Parkinson’s disease.

Meiser, J. & Grünewald, A.

1/09/20 → 31/08/23

Project: Research

ACTIVASION: Actin cytoskeleton remodeling in tumor immune evasion - mechanisticaspects

Thomas, C.

15/07/20 → 14/02/24

Project: Research

SMART GLIOBLASTOMA: SMART GLIOBLASTOMA: Signaling and Modulation of the AtypicalIsoform of the CXCR3 RecepTor in glioblastoma cells

Chevigne, A., Niclou, S., Rogister, B., Hanson, J. & D'Uonnolo, G.

Collaboration Fondation Cancer - FNR , Plooschter Projet a.s.b.l., FNRS - Fonds National de la Recherche Scientifique

15/05/20 → 14/10/24

Project: Research

TIME-CLL: Characterization of the tumor and its microenvironment in chronic lymphocytic leukemia

Paggetti, J., Moussay, E. & Fernandez Botana, I.

29/04/20 → 31/03/26

Project: Research

EVIL: Reprogramming of the leukemic microenvironment by small extracellular vesicles: from characterization totherapeutic application

Paggetti, J., Moussay, E. & Morande, P. E.

Collaboration Fondation Cancer - FNR , European Commission

29/04/20 → 31/03/26

Project: Research

SHIFT: Shifting immune-suppressed monocyte-derived macrophage programs into microglia-like reactive cells in Glioblastoma

Michelucci, A.

Lions Clubs International

1/01/20 → 31/12/22

Project: Research

METGLIO: eEF1A1K165 methylation modulator of protein synthesis and promoter of glioma tumorigenesis

Dittmar, G. & Niclou, S.

1/01/20 → 14/06/23

Project: Research

ACTIPHAGY: Actin remodeling in autophagy-mediated tumor immune escape,mechanistic aspects

Thomas, C., Janji, B. & Biolato, A. M.

1/12/19 → 30/04/24

Project: Research

HAB-CLL: Role of AHR and HIF1α transcription factors in normal and chroniclymphocytic leukemia B lymphocytes

Moussay, E., Paggetti, J. & Gonder, S.

1/10/19 → 29/02/24

Project: Research

Try-IBD: Multi-dimensional resolution of tryptophan-driven immune-metabolism as a novel pathophysiologicalprinciple in inflammatory bowel disease

Meiser, J., Aden, K., Ogris, C. & Pravdivtsev, A.

Fondatioun Kriibskrank Kanner

1/09/19 → 30/11/24

Project: Research

NEUROIMMUNOTHERAPY PHASE II: Combining JQI and PD-1 as an innovative approach for the treatment of Childhood Neuroblastoma.

Janji, B. & Berchem, G.

1/07/19 → 30/06/23

Project: Research

CANBIO (Hugo Dosquet): Development of methodologies for monitoring cancer progression and predicting treatment response

Azuaje, F. & Dosquet, H.

1/01/19 → 31/12/22

Project: Research

COMBATIC 2018: Improving T-cell and Macrophage Immune checkpoint blockades by combining autophagy inhibitors

1/01/19 → 31/07/23

Project: Research

GBModImm: Innovative Models and Oncolytic Viruses for Immunotherapy of Glioblastoma

Niclou, S., Marchini, A., Bours, V., Robe, P. & Salvato, I.

1/11/18 → 31/01/23

Project: Research

1cFlux: Understanding and targeting the function of formate overflow in cancer ce

Meiser, J.

1/09/18 → 31/08/23

Project: Research

Chair in Neuropathology: NPath

Niclou, S., Balling, R. & Mittelbronn, M.

1/01/17 → 31/12/22

Project: Research

CANBIO (PRG Management): Training in Cancer Biology: Focus on Tumour Escape Mechanisms

Niclou, S.

15/10/16 → 14/04/23

Project: Research

Optimization of image acquisition protocols in Magnetic resonance Imaging (MRI) in oncology and neurology applications

Keunen, O. & Kanli, G.

MR Solutions Ltd.

1/10/15 → 31/12/22

Project: Consultancy

IVIP: In Vivo Imaging Platform

Keunen, O. & Kanli, G.

1/01/15 → 31/12/22

Project: Research

Not started

CombiN: mproving the Therapeutic benefit of immunotherapy in Neuroblastoma by combining autophagy inhibitor and anti-PD-i