Department of Cancer Research

Active

ACTICAM: Role of ICAM-1 in mediating actin remodeling-dependent tumor immune evasion

Thomas, C. & Pereira Fernandes, D.

1/10/23 → 30/09/25

Project: Research

RESTAGE: NR1D2 circadian clock gene as a target for reverting glioblastoma associated-immunosuppression via functional modulation of myeloid cells.

Poli, A. & Michelucci, A.

1/10/23 → 30/09/25

Project: Research

CANBIO2 (Lucie Rospape): Bioengineered small extracellular vesicles (sEV) as new cancer immunotherapies to counteract immune suppression

Paggetti, J. & Rospape, L.

FNR - Fonds National de la Recherche

1/10/23 → 30/09/27

Project: Research

Nextimmune-2 (Alice Verdier): Immunometabolism adaptation in leukemia/lymphoma and new therapeutic opportunities

Moussay, E. & Verdier, A.

FNR - Fonds National de la Recherche

1/10/23 → 30/09/27

Project: Research

MOFIC: Deciphering the role of the microbiome-derived oncometabolite formate on the immune cell compartment in colorectal cancer

Letellier, E., Meiser, J. & Wilmes, P.

1/10/23 → 30/09/25

Project: Research

CANBIO2 (Eleonora Campus): Elucidating the role of the IRG1/ACOD1-itaconate axis in TAMs polarization in glioblastoma

Michelucci, A. & Campus, E.

FNR - Fonds National de la Recherche

15/09/23 → 14/09/27

Project: Research

CANBIO2 (Ana Catarina Almeida): Harnessing DNA repair factors to promote an innate immune response against glioblastoma

Van Dyck, E. & Almeida, A. C.

FNR - Fonds National de la Recherche

1/09/23 → 31/08/27

Project: Research

PLASTIG: TACKLING TUMOR HETEROGENEITY AND PLASTICITY AS RESISTANCE MECHANISMS IN GLIOBLASTOMA

Golebiewska, A.

FNR - Fonds National de la Recherche

1/09/23 → 31/08/26

Project: Research

ASH AWARD_2023: American Society of Hematology Global Research Award

Morande, P. E.

American Association of Hematology

1/08/23 → 31/07/26

Project: Research

CCI4EU: Strengthening research capacities of comprehensive cancer infrastructures

Niclou, S. & Michel, T.

1/05/23 → 30/04/26

Project: Research

MONO-GLIO: Prognostic impact of circulating monocyte subsets in glioblastoma patients

Michelucci, A.

Scailyte

1/04/23 → 31/03/25

Project: Research

IPerGlio: Improving personalized glioblastoma care by intertwined immunomics and artificial intelligence approaches

Cosma, A. & Nazarov, P.

FNR - Fonds National de la Recherche

1/04/23 → 31/03/26

Project: Research

iNEW: Role for the Itaconate/Nrf2 axis in metabolic and epigenetic reprogramming of neonatal macrophages

Meiser, J. & Ohl, K.

1/03/23 → 31/05/25

Project: Research

ATLANTIS: Targeting homologous recombination and replication stress in glioblastoma: from molecular insights to synthetic lethality approaches

Van Dyck, E. & Yi, T.

FNR - Fonds National de la Recherche

1/03/23 → 28/02/27

Project: Research

CANBIO2 (Maryna Chepeleva): Deconvolution of complex molecular signals of metabolomics and transcriptomics for predicting drug sensitivity and therapy resistance in malignant melanoma

Nazarov, P. & Chepeleva, M.

FNR - Fonds National de la Recherche

1/03/23 → 28/02/27

Project: Research

Nextimmune-2 (Mónica Miranda de la Maza): Impact of the interplay between microglia, astrocytes and infiltrating immune cells in neuroinflammatory mechanisms in Alzheimer’s disease.

Mittelbronn, M., Bouvier, D. S. & Miranda de la Maza, M.

FNR - Fonds National de la Recherche

1/02/23 → 31/01/27

Project: Research

TARGET-CLL: DEVELOPMENT OF NEW TOOLS AND THERAPEUTICS FOR CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

Moussay, E., Paggetti, J. & Viry, E.

1/02/23 → 31/01/25

Project: Research

CombiN (Elisabetta Bartolini): Improving the Therapeutic benefit of immunotherapy in Neuroblastoma by combining autophagy inhibitor and anti-PD-i

Janji, B. & Bartolini, E.

Stiftelsen Cancera

1/02/23 → 31/01/27

Project: Research

CANBIO2 (Chloé Duculty): Overcoming treatment resistance with new therapeutic opportunities in leukaemia

Moussay, E. & Duculty, C.

FNR - Fonds National de la Recherche

1/01/23 → 31/12/26

Project: Research

1cRedox: Targeting ALDH1L2 to enforce ER stress sensitivity of cancer cells

Becker, B.

1/11/22 → 31/01/25

Project: Research

ACTIDRUG: High-content drug screening to inhibit actin cytoskeleton-mediated cancer immune evasion

Thomas, C. & Mgrditchian, T.

1/10/22 → 30/09/24

Project: Research

KILLERCD4-CLL: CYTOTOXIC CD4+ T CELLS AS NOVEL IMMUNOTHERAPY IN CLL AND OTHER B-CELL MALIGNANCIES

Paggetti, J., Moussay, E. & Borne, C.

1/10/22 → 30/09/24

Project: Research

EPIPHARM: IMPACT OF EPITRANSCRIPTOMIC REGULATION ON RESPONSE TO PHARMACOLOGICAL TREATMENTS IN GLIOMAS

Golebiewska, A., Fritah, S. & Niclou, S.

Fondation de Luxembourg

1/10/22 → 30/09/24

Project: Research

Pseudo PET: Pseudo PET imaging of brain tumor hypoxia

Keunen, O. & Niclou, S.

1/10/22 → 30/09/24

Project: Research

CANBIO2 (PRG Management): CANBIO2

Niclou, S. & Meiser, J.

1/10/22 → 30/06/29

Project: Research

CraNE: Creation of National Comprehensive Cancer Centres and EU Networking

Niclou, S.

1/10/22 → 30/09/24

Project: Research

I2TRON Vanessa Klapp: Immunotherapies and drug screening in improved patient-derived models: a translational approach towards personalized treatments for leukaemia

Paggetti, J., Klapp, V. & Moussay, E.

FNR - Fonds National de la Recherche

1/09/22 → 30/08/26

Project: Research

PreCyse: Predictive biomarker profile for tumour and patient stratification for CyPep-1 guided ICI-therapy

Janji, B. & Poussard, M.

FNR - Fonds National de la Recherche

1/09/22 → 30/11/25

Project: Research

GLIORESOLVE: Training of next generation of European glioblastoma (translational) researchers, to resolve precision targeting of the brain tumour microenvironment

Golebiewska, A., Niclou, S. & de Lucas Sanz, M.

European Commission

1/09/22 → 31/08/25

Project: Research

1cFlex: Understanding the Flexibility of 1C metabolism and its role during metastatic dissemination of cancer cell

Meiser, J., Letellier, E. & Chen, O.

Collaboration Fondation Cancer - FNR

1/09/22 → 30/09/26

Project: Research

Synapodia: Novel synaptic filopodium-like protrusions (SFPs) protect tumor cells against cytotoxic lymphocyte-mediated killing

Thomas, C., Filali, L. & Moreau, F.

FNR - Fonds National de la Recherche, Fondation Cancer

15/07/22 → 14/10/24

Project: Research

DIOMEDES: Deconvolution of heterogeneity in the Glioblastoma cellular ecosystem for understanding treatment resistance and improving patient stratification

Golebiewska, A., Nazarov, P., Mittelbronn, M., Skupin, A., Zinovyev, A., Bjerkvig, R., Brown, D., Lukashiv, T., Nosirov, B. & Dording, C.

FNR - Fonds National de la Recherche, Fondation Cancer

1/07/22 → 30/06/25

Project: Research

EVceptor: Role of chemokine receptor-bearing extracellular vesicles in leukaemia and lymphoma

Chevigne, A., Paggetti, J., Szpakowska, M. & Bonnemain-Pascual, H.

FNRS - Fonds National de la Recherche Scientifique

1/05/22 → 30/04/24

Project: Research

INCITE: Investigating the role of CMTM proteins in the regulation of PD-L1 expression

Janji, B.

FNRS - Fonds National de la Recherche Scientifique

1/04/22 → 30/08/24

Project: Research

C2I: CHECKPOINT INHIBITORS IMPROVEMENT FOR THE TREATMENT OF CANCER

Janji, B., Gao, R. & Van Moer, K.

FNR - Fonds National de la Recherche

1/04/22 → 31/10/25

Project: Research

SUNRISE (TLV-PDR-2021): TARGETING TUMOR PROPAGATING CELLS IN GLIOBLASTOMA: FROM MECHANISTICINSIGHTS TO PRECISION MEDICINE

Van Dyck, E., Rogister, B., Neirinckx, V., Nazarov, P. & Pailas, A.

Fondation du Pélican de Mie et Pierre Hippert-Faber, FNRS - Fonds National de la Recherche Scientifique

1/03/22 → 28/02/26

Project: Research

RNA Therapeutic: In search of RNA Therapeutic Drugs in Oncology

Fritah, S., Golebiewska, A. & Adiamah, M.

1/03/22 → 28/02/24

Project: Research

NIMBUS: Roles of the epigenetic reader MBD1 in IDH1-mutated gliomas

Van Dyck, E. & Fritah, S.

FNRS - Fonds National de la Recherche Scientifique

17/01/22 → 16/10/24

Project: Research

RESCOM-2021: 5th Lecture Series in Cancer Research

Niclou, S. & Janji, B.

FNR - Fonds National de la Recherche

3/01/22 → 31/12/24

Project: Other

CancerProfile: Predictive and personalized medicine of pancreatic cancer

Mittelbronn, M.

1/01/22 → 30/01/26

Project: Research

TRICK-ALDH: Assessment the impact of selective ALDH1 inhibitors on tumor infiltrating lymphocytes and the therapeutic benefit of Immune checkpoint blockers

Berchem, G., Janji, B. & Kumar, A.

Advanced BioDesign

1/01/22 → 30/06/24

Project: Research

IMPACT 21: IMPROVING CANCER IMMUNOTHERAPY BY TARGETING HYPOXIA

Janji, B. & Benoit, A.

FNRS - Fonds National de la Recherche Scientifique

1/11/21 → 1/12/25

Project: Research

I2TRON Kim Eiden: The role of mitochondrial folate metabolism during macrophage polarization (Mac1L)

Meiser, J. & Eiden, K.

FNR - Fonds National de la Recherche

15/10/21 → 14/10/25

Project: Research

TERMINI: Roles of NEIL3 DNA glycosylase in telomere dynamics and DNA demethylation in glioblastoma: From molecular insights topreclinical target validation

Van Dyck, E. & Baidarjad, H.

FNR - Fonds National de la Recherche, Lions Clubs International

1/07/21 → 30/06/24

Project: Research

ImmoGBM: ImmoGBM

Golebiewska, A., Bours, V., Robe, P., Rezaeipour, M. & Niclou, S.

FNRS - Fonds National de la Recherche Scientifique

1/06/21 → 31/05/25

Project: Research

GLASS-LUX: Glioma Longitudinal AnalySiS in Luxembourg (GLASS-LUX): ex vivo and in vivo Functional Profiling of Recurrent Gliomas

Golebiewska, A., Niclou, S., Nazarov, P., Kwon, Y., Klink, B. & Krokhmal, I.

Collaboration Fondation Cancer - FNR , FNR - Fonds National de la Recherche

1/06/21 → 31/12/25

Project: Research

PFP: Personalized Functional Profiling - PFP

Mittelbronn, M. & Michel, T.

1/05/21 → …

Project: Research

MelCol_PFP: PERSONAL FUNCTIONAL PROFILING FOR DRUG DISCOVERY IN MELANOMA AND COLORECTAL CANCER

El Khoury, V. & Cutrona, M.

FNR - Fonds National de la Recherche

1/04/21 → 31/03/25

Project: Research

I2TRON Elena Ockfen: Biological and clinical implications of PD-L1 protein polarization at the tumor tissue and cell levels

Thomas, C. & Ockfen, E.

FNR - Fonds National de la Recherche

1/03/21 → 28/02/25

Project: Research

I2TRON Frida Lind-Holm Mogensen: Microglia programs under PARK7/DJ-1 deficiency, a genetic cause of Parkinson’s disease

Michelucci, A. & Lind-Holm, F.

FNR - Fonds National de la Recherche

15/02/21 → 14/02/25

Project: Research

Department of Cancer Research

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