Department of Cancer Research

Luxembourg Institute of Health

Websitehttps://www.lih.lu/en/research-scope/research-department/department-of-cancer-research/

3 Not started
64 Active
92 Finished

1 - 50 out of 159 results

Active
RADIO-D2R2: Radiomics for the differential diagnosis of radio-necrosis vs. progression after stereotactic radiotherapy of oligometastasis
Keunen, O. (PI), Vogin, G. (CoPI), Nazarov, P. (Partner), Zhang, L. (Participant) & Palissot, V. (Participant)
1/10/24 → 30/09/26
Project: Research
CANBIO2 (Wanxin Huang): Reciprocal effects of intrinsic tumour immune resistance and the tumour microenvironment
Thomas, C. (PI) & Huang, W. (PhD Student)
FNR - Fonds National de la Recherche
1/09/24 → 31/08/28
Project: Research
TNT2-CLL: Translation as Novel Therapeutic Target in CLL
Paggetti, J. (PI) & Moussay, E. (CoPI)
1/06/24 → 31/05/26
Project: Research
MVD: Minimal Viable Dataset
Meiser, J. (PI), Fagherazzi, G. (Partner), Fünfgeld, M. (Partner), Bahlawane, C. (Partner), Herkenne, E. (Partner), Kalmanti, D. (Partner) & Tonini, M. M. (Partner)
1/06/24 → …
Project: Other
T3L2: Translation as novel therapeutic target in leukemia/lymphoma
Moussay, E. (PI) & Paggetti, J. (Partner)
Fondation Cancer
1/05/24 → 30/04/27
Project: Research
4M8: Formate-dependent Regulation of Cancer Metastasis
Meiser, J. (PI)
1/05/24 → 30/04/29
Project: Research
NANO-SCOPE: Pre-operative methylation-based brain tumor classification
Toth, R. (CoPI), Frauenknecht, K. (CoPI) & Tabbakh, D. (PhD Student)
FNR - Fonds National de la Recherche
1/04/24 → 30/06/27
Project: Research
PEAR-OP: Personalized Medicine Acceleration through Rapid Omics Profiling
Toth, R. (PI), Nazarov, P. (CoPI), Dittmar, G. (CoPI), Frauenknecht, K. (Partner) & STEFANIZZI, F. M. (Participant)
1/04/24 → 31/03/26
Project: Research
INCEPTOR: Investigating the mode of action of ACB1801 on increasing TAP1 and improving cancer immunotherapy
Janji, B. (Scientific Advisor/Mentor) & Ramos, T. (PI)
European Commission
1/04/24 → 31/03/26
Project: Research
MITOFIT: The importance of being MitoFit: targeting mitochondrial metabolism in glioblastoma multiforme
Golebiewska, A. (PI) & Meiser, J. (CoPI)
FNR - Fonds National de la Recherche
1/03/24 → 31/05/27
Project: Research
ReForMCaS: Delineating the role of caclium signaling in controlling formate overflow
Meiser, J. (PI) & Voorsluijs, V. (Partner)
1/03/24 → 31/05/27
Project: Research
CANBIO2 (Hamed Allahverdi): Tumour plasticity as a treatment resistance mechanism in glioblastoma.
Golebiewska, A. (PI) & Allahverdi, H. (PhD Student)
FNR - Fonds National de la Recherche
1/12/23 → 30/11/27
Project: Research
PIANO: Impact of intratumoral heterogeneity on treatment resistance and tumor relapse in glioblastoma
Van Dyck, E. (PI), Mittelbronn, M. (CoPI), Rogister, B. (CoPI), Neirinckx, V. (CoPI) & Torres Fernández, M. (PhD Student)
15/11/23 → 30/11/25
Project: Research
CANBIO2 (Gautham Srinivasan): Identifying metabolic vulnerabilities in 3D
Meiser, J. (PI) & Srinivasan, G. (PhD Student)
FNR - Fonds National de la Recherche
4/10/23 → 3/10/27
Project: Research
ACTICAM: Role of ICAM-1 in mediating actin remodeling-dependent tumor immune evasion
Thomas, C. (PI) & Pereira Fernandes, D. (PhD Student)
1/10/23 → 30/09/25
Project: Research
Nextimmune-2 (Alice Verdier): Immunometabolism adaptation in leukemia/lymphoma and new therapeutic opportunities
Moussay, E. (PI) & Verdier, A. (PhD Student)
FNR - Fonds National de la Recherche
1/10/23 → 30/09/27
Project: Research
MOFIC: Deciphering the role of the microbiome-derived oncometabolite formate on the immune cell compartment in colorectal cancer
Letellier, E. (PI), Meiser, J. (CoPI) & Wilmes, P. (CoPI)
1/10/23 → 30/09/25
Project: Research
CANBIO2 (Lucie Rospape): Bioengineered small extracellular vesicles (sEV) as new cancer immunotherapies to counteract immune suppression
Paggetti, J. (PI) & Rospape, L. (PhD Student)
FNR - Fonds National de la Recherche
1/10/23 → 30/09/27
Project: Research
TiTLe: Role of the transcription factors AHR and HIF-1alpha in the suppressive ability of regulatory T cells in chronic lymphocytic leukemia
Moussay, E. (PI) & Paggetti, J. (CoPI)
1/10/23 → 30/09/25
Project: Research
RESTAGE: NR1D2 circadian clock gene as a target for reverting glioblastoma associated-immunosuppression via functional modulation of myeloid cells.
Poli, A. (PI) & Michelucci, A. (CoPI)
1/10/23 → 30/09/25
Project: Research
CANBIO2 (Eleonora Campus): Elucidating the role of the IRG1/ACOD1-itaconate axis in TAMs polarization in glioblastoma
Michelucci, A. (PI) & Campus, E. (PhD Student)
FNR - Fonds National de la Recherche
15/09/23 → 14/09/27
Project: Research
CANBIO2 (Ana Catarina Almeida): Harnessing DNA repair factors to promote an innate immune response against glioblastoma
Van Dyck, E. (PI) & Almeida, A. C. (PhD Student)
FNR - Fonds National de la Recherche
1/09/23 → 31/08/27
Project: Research
PLASTIG: TACKLING TUMOR HETEROGENEITY AND PLASTICITY AS RESISTANCE MECHANISMS IN GLIOBLASTOMA
Golebiewska, A. (PI)
FNR - Fonds National de la Recherche
1/09/23 → 30/11/26
Project: Research
ASH AWARD_2023: American Society of Hematology Global Research Award
Morande, P. E. (PI)
American Association of Hematology
1/08/23 → 31/07/26
Project: Research
ECHOS: Establishing of national cancer mission hubs and creation of network to support the mission on cancer
Niclou, S. (Partner) & Geffers, L. (CoPI)
1/05/23 → 30/04/26
Project: Research
CCI4EU: Strengthening research capacities of comprehensive cancer infrastructures
Niclou, S. (Partner) & Michel, T. (CoPI)
1/05/23 → 30/04/26
Project: Research
MONO-GLIO: Prognostic impact of circulating monocyte subsets in glioblastoma patients
Michelucci, A. (PI)
Scailyte
1/04/23 → 31/03/25
Project: Research
IPerGlio: Improving personalized glioblastoma care by intertwined immunomics and artificial intelligence approaches
Cosma, A. (PI), Nazarov, P. (Partner) & Drissi Yahyaoui, L. (PhD Student)
FNR - Fonds National de la Recherche
1/04/23 → 31/03/26
Project: Research
ATLANTIS: Targeting homologous recombination and replication stress in glioblastoma: from molecular insights to synthetic lethality approaches
Van Dyck, E. (PI) & Yi, T. (PhD Student)
FNR - Fonds National de la Recherche
1/03/23 → 28/02/27
Project: Research
iNEW: Role for the Itaconate/Nrf2 axis in metabolic and epigenetic reprogramming of neonatal macrophages
Meiser, J. (PI) & Ohl, K. (PI)
1/03/23 → 31/05/26
Project: Research
CANBIO2 (Maryna Chepeleva): Deconvolution of complex molecular signals of metabolomics and transcriptomics for predicting drug sensitivity and therapy resistance in malignant melanoma
Nazarov, P. (PI) & Chepeleva, M. (PhD Student)
FNR - Fonds National de la Recherche
1/03/23 → 28/02/27
Project: Research
TARGET-CLL: DEVELOPMENT OF NEW TOOLS AND THERAPEUTICS FOR CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Moussay, E. (PI), Paggetti, J. (CoPI) & Viry, E. (Partner)
1/02/23 → 31/01/25
Project: Research
CombiN (Elisabetta Bartolini): Improving the Therapeutic benefit of immunotherapy in Neuroblastoma by combining autophagy inhibitor and anti-PD-i
Janji, B. (PI) & Bartolini, E. (PhD Student)
Stiftelsen Cancera
1/02/23 → 31/01/27
Project: Research
Nextimmune-2 (Mónica Miranda de la Maza): Impact of the interplay between microglia, astrocytes and infiltrating immune cells in neuroinflammatory mechanisms in Alzheimer’s disease.
Mittelbronn, M. (PI), Bouvier, D. S. (PI) & Miranda de la Maza, M. (PhD Student)
FNR - Fonds National de la Recherche
1/02/23 → 31/01/27
Project: Research
MRI-PLATOC: MRI Platform Operation Continuity
Keunen, O. (PI) & Kanli, G. (Participant)
1/01/23 → 31/12/25
Project: Consultancy
CANBIO2 (Chloé Duculty): Overcoming treatment resistance with new therapeutic opportunities in leukaemia
Moussay, E. (PI) & Duculty, C. (PhD Student)
FNR - Fonds National de la Recherche
1/01/23 → 31/12/26
Project: Research
CANBIO2 (PRG Management): CANBIO2
Niclou, S. (PI) & Meiser, J. (PI)
1/01/23 → 30/06/29
Project: Research
1cRedox: Targeting ALDH1L2 to enforce ER stress sensitivity of cancer cells
Becker, B. (PI)
1/11/22 → 31/01/25
Project: Research
GLIORESOLVE: Training of next generation of European glioblastoma (translational) researchers, to resolve precision targeting of the brain tumour microenvironment
Golebiewska, A. (PI), Niclou, S. (Partner) & de Lucas Sanz, M. (PhD Student)
European Commission
1/09/22 → 31/08/26
Project: Research
PreCyse: Predictive biomarker profile for tumour and patient stratification for CyPep-1 guided ICI-therapy
Janji, B. (PI) & Poussard, M. (Partner)
FNR - Fonds National de la Recherche
1/09/22 → 30/11/25
Project: Research
1cFlex: Understanding the Flexibility of 1C metabolism and its role during metastatic dissemination of cancer cell
Meiser, J. (PI), Letellier, E. (CoPI) & Chen, O. (Partner)
Collaboration Fondation Cancer - FNR
1/09/22 → 30/09/26
Project: Research
I2TRON Vanessa Klapp: Immunotherapies and drug screening in improved patient-derived models: a translational approach towards personalized treatments for leukaemia
Paggetti, J. (PI), Klapp, V. (PhD Student) & Moussay, E. (CoPI)
FNR - Fonds National de la Recherche
1/09/22 → 30/08/26
Project: Research
Synapodia: Novel synaptic filopodium-like protrusions (SFPs) protect tumor cells against cytotoxic lymphocyte-mediated killing
Thomas, C. (PI), Filali, L. (CoPI) & Moreau, F. (Partner)
Collaboration Fondation Cancer - FNR
15/07/22 → 14/04/25
Project: Research
DIOMEDES: Deconvolution of heterogeneity in the Glioblastoma cellular ecosystem for understanding treatment resistance and improving patient stratification
Golebiewska, A. (PI), Nazarov, P. (CoPI), Mittelbronn, M. (Partner), Skupin, A. (PI), Zinovyev, A. (CoPI), Bjerkvig, R. (CoPI), Brown, D. (CoPI), Lukashiv, T. (Partner), Nosirov, B. (Partner) & Dording, C. (Partner)
FNR - Fonds National de la Recherche
1/07/22 → 30/06/25
Project: Research
EVceptor: Role of chemokine receptor-bearing extracellular vesicles in leukaemia and lymphoma
Chevigne, A. (PI), Paggetti, J. (CoPI), Szpakowska, M. (CoPI) & Bonnemain-Pascual, H. (PhD Student)
FNRS - Fonds National de la Recherche Scientifique
1/05/22 → 30/04/26
Project: Research
INCITE: Investigating the role of CMTM proteins in the regulation of PD-L1 expression
Janji, B. (PI), Ramos, T. (Partner) & Gao, R. (Partner)
FNRS - Fonds National de la Recherche Scientifique
1/04/22 → 14/03/25
Project: Research
SUNRISE (TLV-PDR-2021): TARGETING TUMOR PROPAGATING CELLS IN GLIOBLASTOMA: FROM MECHANISTICINSIGHTS TO PRECISION MEDICINE
Van Dyck, E. (PI), Rogister, B. (CoPI), Neirinckx, V. (CoPI), Nazarov, P. (CoPI) & Pailas, A. (PhD Student)
Fondation du Pélican de Mie et Pierre Hippert-Faber, FNRS - Fonds National de la Recherche Scientifique
1/03/22 → 28/02/26
Project: Research
NIMBUS: Roles of the epigenetic reader MBD1 in IDH1-mutated gliomas
Van Dyck, E. (PI), Fritah, S. (CoPI) & Tourneur, L. (PhD Student)
FNRS - Fonds National de la Recherche Scientifique
17/01/22 → 16/10/26
Project: Research
RESCOM-2021: 5th Lecture Series in Cancer Research
Niclou, S. (PI) & Janji, B. (PI)
FNR - Fonds National de la Recherche
3/01/22 → 31/12/24
Project: Other
CancerProfile: Predictive and personalized medicine of pancreatic cancer
Mittelbronn, M. (PI) & El Khoury, V. (PI)
1/01/22 → 15/10/25
Project: Research