Projects per year
Organisation profile
Organisation profile
The main mission of the Department of Cancer Research is to advance the treatment options of cancer and reduce the cancer burden within the Luxembourg population and beyond. We do so through research excellence in priority areas covering the basic, translational and clinical research landscape to foster personalised medicine programs. Our activities focus on difficult to treat cancers and our teams have dedicated expertise in cancer immunology, the tumour microenvironment, tumor metabolism and neuro-oncology. We explore the cellular and molecular mechanisms of tumor progression using a wide range of state-of-the-art technologies, including multimodal omics technologies (genomics, metabolomics…), advanced immunoprofiling analyses, as well as ex vivo and in vivo imaging modalities leveraging patient data and innovative patient-derived models for cancer research.
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Collaborations and top research areas from the last five years
Profiles
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IMMUNOGENCODE: Decoding the impact of germline and somatic genetic variation on anti-tumoral immunity and immunotherapy efficacy in brain metastatic tumors
Alvarez Prado, A. F. (PI) & Meiser, J. (Scientific Advisor/Mentor)
FNR - Fonds National de la Recherche
15/01/25 → 14/07/30
Project: Research
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FM2MRI: Foundation Multi-modal Model for Modality Synthesis & Segmentation of Magnetic Resonance Images
Ghamizi, S. (PI) & Keunen, O. (Scientific Advisor/Mentor)
FNR - Fonds National de la Recherche
5/01/25 → 5/10/27
Project: Research
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A comprehensive guide to study the immunological synapse using imaging flow cytometry
Biolato, A. M., Filali, L., Krecke, M., Thomas, C. & Hoffmann, C., 5 Feb 2025, In: Methods in Cell Biology. 193, p. 69-97Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids
Salvato, I., Klein, E., Poli, A., Rezaeipour, M., Ermini, L., Nosirov, B., Lipsa, A., Oudin, A., Baus, V., Dore, G. M., Cosma, A., Golebiewska, A., Marchini, A. & Niclou, S. P., Mar 2025, In: Molecular Oncology. 19, 3, p. 682-697 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Association of LEF1-AS1 with cardiovascular and neurological complications of COVID-19
Vausort, M., Lumley, A. I., Boubakeur, H., Zhang, L., Hefeng, F. Q., Ollert, M., Wilmes, P., Fagherazzi, G. & Devaux, Y., Mar 2025, In: Journal of Molecular and Cellular Cardiology Plus. 11, 8 p., 100280.Research output: Contribution to journal › Article › Research › peer-review
Open Access