Projects per year
Organisation profile
Organisation profile
The main mission of the Department of Cancer Research is to advance the treatment options of cancer and reduce the cancer burden within the Luxembourg population and beyond. We do so through research excellence in priority areas covering the basic, translational and clinical research landscape to foster personalised medicine programs. Our activities focus on difficult to treat cancers and our teams have dedicated expertise in cancer immunology, the tumour microenvironment, tumor metabolism and neuro-oncology. We explore the cellular and molecular mechanisms of tumor progression using a wide range of state-of-the-art technologies, including multimodal omics technologies (genomics, metabolomics…), advanced immunoprofiling analyses, as well as ex vivo and in vivo imaging modalities leveraging patient data and innovative patient-derived models for cancer research.
Fingerprint
Collaborations and top research areas from the last five years
Profiles
-
CAMEL: The one-carbon metabolism as novel therapeutic target in leukemia/lymphoma
Paggetti, J. (PI), Meiser, J. (CoPI), Viry, E. (Partner), Marttila, P. (Partner) & Pierson, S. (Partner)
1/07/25 → 30/09/28
Project: Research
-
CANBIO2 (Perez Climent): Decoding the impact of genetic variation on anti-tumoral immunity and immunotherapy efficacy in brain metastatic tumors
Álvarez-Prado, Á. (PI) & Perez Climent, P. (PhD Student)
FNR - Fonds National de la Recherche
15/06/25 → 14/06/29
Project: Research
-
CANBIO2 (NN - Project 21): Integrative multi-omics analysis of IDH mutant gliomas to reveal novel targets for treatment
Fritah, S. (PI) & Metta, G. (PhD Student)
FNR - Fonds National de la Recherche
1/06/25 → 31/05/29
Project: Research
-
A comprehensive guide to study the immunological synapse using imaging flow cytometry
Biolato, A. M., Filali, L., Krecke, M., Thomas, C. & Hoffmann, C., 5 Feb 2025, In: Methods in Cell Biology. 193, p. 69-97Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Adaptation to Arginine Deprivation Leads to a More Aggressive, Therapy-Resistant Phenotype in HNSCC Cells
Chen, O., Vovk, O., Polishchuk, N., Mayevska, O., Shuvayeva, G., Demir, M., Lukiyanchuk, V., Kunz-Schughart, L. A., Dubrovska, A. & Stasyk, O., 19 Jun 2025, In: Biomolecules. 15, 6, 20 p., 900.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids
Salvato, I., Klein, E., Poli, A., Rezaeipour, M., Ermini, L., Nosirov, B., Lipsa, A., Oudin, A., Baus, V., Dore, G. M., Cosma, A., Golebiewska, A., Marchini, A. & Niclou, S. P., Mar 2025, In: Molecular Oncology. 19, 3, p. 682-697 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access