Projects per year
Organization profile
Organisation profile
Mission/Activities
The Cardiovascular Research Unit aims to better understand the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and therapeutic approaches to personalise health care. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.
Research projects
Our ongoing research projects address two major areas:
- Biomarkers
Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.
- Therapeutics
By focusing on the mechanisms that RNAs regulate the development of diseases, the group aims to facilitate drug discovery.
Strategic goals
- Address the main causes of mortality and morbidity in developed countries: heart and braindiseases
- Fulfil unmet medical needs: lack of diagnostic tools and drugs forpersonalisedhealthcare
- Develop networks of international collaborators
- Collaborate with private partners to bring research products to clinical application
- Perform translational research to push forward personalised medicine.
Fingerprint
Network
Profiles
-
-
MAACS: N6 - methyladenosine RNA modification in acute coronary syndrome
1/03/23 → 28/02/25
Project: Research
-
Association of diet quality indices with serum and metabolic biomarkers in participants of the ORISCAV-LUX-2 study
Vahid, F., Hoge, A., Hébert, J. R., Bohn, T., Alkerwi, A., Noppe, S., Delagardelle, C., Beissel, J., Chioti, A., Stranges, S., Schmit, J. C., Lair, M. L., D’Incau, M., Pastore, J., Aguayo, G., Le Coroller, G., Vaillant, M., Samouda, H., Appenzeller, B., Malisoux, L., & 10 others , 14 Mar 2023, (E-pub ahead of print) In: European Journal of Nutrition.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Call for participation in the AtheroNET COST Action to implement multiomics in atherosclerotic cardiovascular disease research
Sopic, M., Kararigas, G., Devaux, Y. & Magni, P., 12 Apr 2023, (E-pub ahead of print) In: European Heart Journal.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Cardiovascular complications of diabetes: role of non-coding RNAs in the crosstalk between immune and cardiovascular systems
Spinetti, G., Mutoli, M., Greco, S., Riccio, F., Ben-Aicha, S., Kenneweg, F., Jusic, A., de Gonzalo-Calvo, D., Nossent, A. Y., Novella, S., Kararigas, G., Thum, T., Emanueli, C., Devaux, Y. & Martelli, F., Dec 2023, In: Cardiovascular Diabetology. 22, 1, 122.Research output: Contribution to journal › Review article › peer-review
Open Access