Projects per year
Organisation profile
Organisation profile
Mission/Activities
The Cardiovascular Research Unit aims to better understand the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and therapeutic approaches to personalise health care. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.
Research projects
Our ongoing research projects address two major areas:
- Biomarkers
Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.
- Therapeutics
By focusing on the mechanisms that RNAs regulate the development of diseases, the group aims to facilitate drug discovery.
Strategic goals
- Address the main causes of mortality and morbidity in developed countries: heart and braindiseases
- Fulfil unmet medical needs: lack of diagnostic tools and drugs forpersonalisedhealthcare
- Develop networks of international collaborators
- Collaborate with private partners to bring research products to clinical application
- Perform translational research to push forward personalised medicine.
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Collaborations and top research areas from the last five years
Profiles
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TreatPD: An RNA to treat Parkinson’s disease
Devaux, Y. (PI)
FNR - Fonds National de la Recherche
1/03/26 → 31/05/29
Project: Research
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OxiPARK: Mitochondria targeting RNAs involved in oxidative stress and Parkinson’s Disease
Devaux, Y. (PI) & Kalmes, C. (PhD Student)
FNR - Fonds National de la Recherche
15/09/25 → 14/09/29
Project: Research
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RVHF: Long noncoding RNAs in Right Ventricular Heart Failure towards personalized healthcare
Devaux, Y. (PI) & Acharya, S. (Partner)
FNR - Fonds National de la Recherche
1/01/24 → 31/03/28
Project: Research
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Blood N1-methyladenosine (m1A) RNA modification and outcome after cardiac arrest
Stopa, V., Sopic, M., Bernardin, F., Legrave, N. M., Zhang, L., Stammet, P. & Devaux, Y., 25 Feb 2026, In: Critical Care. 30, 1, 12 p., 135.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Direct RNA sequencing identified solute carrier family 2 member 1 to improve neurological outcome prediction after cardiac arrest
Stopa, V., Sopic, M., Zhang, L., Lumley, A., Stammet, P., Schrag, C., Smid, O., Hassager, C., Kjaergaard, J., Pellis, T., Horn, J., Kuiper, M., Hovdenes, J., Rylander, C., Wise, M. P., Nielsen, N. & Devaux, Y., 7 Jan 2026, In: Intensive Care Medicine Experimental. 14, 1, p. 3 3.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Do nurses and allied professionals need to upskill to meet developments in RNA therapeutics for CVD? A discussion paper
Forsyth, F. & Devaux, Y., 16 Jul 2026, In: European Journal of Cardiovascular Nursing. 25, 4, p. 851-857 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access