Projects per year
Organisation profile
Organisation profile
Mission/Activities
The Cardiovascular Research Unit aims to better understand the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and therapeutic approaches to personalise health care. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.
Research projects
Our ongoing research projects address two major areas:
- Biomarkers
Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.
- Therapeutics
By focusing on the mechanisms that RNAs regulate the development of diseases, the group aims to facilitate drug discovery.
Strategic goals
- Address the main causes of mortality and morbidity in developed countries: heart and braindiseases
- Fulfil unmet medical needs: lack of diagnostic tools and drugs forpersonalisedhealthcare
- Develop networks of international collaborators
- Collaborate with private partners to bring research products to clinical application
- Perform translational research to push forward personalised medicine.
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Collaborations and top research areas from the last five years
Profiles
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Xpose (Magali De Carvalho): Molecular responses of dietary and physical activity related exposures and their relationships to cardiovascular health
Devaux, Y. (PI) & De Carvalho, M. (PhD Student)
FNR - Fonds National de la Recherche
1/11/24 → 31/10/28
Project: Research
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RVHF: Long noncoding RNAs in Right Ventricular Heart Failure towards personalized healthcare
Devaux, Y. (PI) & Acharya, S. (Partner)
FNR - Fonds National de la Recherche
1/01/24 → 31/03/28
Project: Research
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HealthyW8: Empowering Healthy Lifestyle Behaviour Through Personalized Intervention Portfolios To Prevent And Control Obesity During Vulnerable Stages Of Life
Bohn, T. (PI), Vahid, F. (Partner), Desai, M. (Partner), Turner, J. (Partner), Devaux, Y. (Partner) & Malisoux, L. (Partner)
1/05/23 → 30/04/28
Project: Research
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A protocol for microRNA extraction from gastrointestinal digesta
Cifuentes Acebal, M., Devaux, Y. & Bohn, T., Jun 2025, In: Food Chemistry: Molecular Sciences. 10, 8 p., 100245.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Association of LEF1-AS1 with cardiovascular and neurological complications of COVID-19
Vausort, M., Lumley, A. I., Boubakeur, H., Zhang, L., Hefeng, F. Q., Ollert, M., Wilmes, P., Fagherazzi, G. & Devaux, Y., Mar 2025, In: Journal of Molecular and Cellular Cardiology Plus. 11, 8 p., 100280.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Circular RNA regulatory role in pathological cardiac remodelling
Bibi, A., Bartekova, M., Gandhi, S., Greco, S., Madè, A., Sarkar, M., Stopa, V., Tastsoglou, S., de Gonzalo-Calvo, D., Devaux, Y., Emanueli, C., Hatzigeorgiou, A. G., Nossent, A. Y., Zhou, Z. & Martelli, F., Jan 2025, In: British Journal of Pharmacology. 182, 2, p. 316-339 24 p.Research output: Contribution to journal › Review article › peer-review
Open Access