Projects per year
Organization profile
Mission/Activities
The Cardiovascular Research Unit aims to better understand the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and therapeutic approaches to personalise health care. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.
Research projects
Our ongoing research projects address two major areas:
- Biomarkers
Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.
- Therapeutics
By focusing on the mechanisms that RNAs regulate the development of diseases, the group aims to facilitate drug discovery.
Strategic goals
- Address the main causes of mortality and morbidity in developed countries: heart and braindiseases
- Fulfil unmet medical needs: lack of diagnostic tools and drugs forpersonalisedhealthcare
- Develop networks of international collaborators
- Collaborate with private partners to bring research products to clinical application
- Perform translational research to push forward personalised medicine.
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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COVIRNA: A diagnostic test to improve surveillance and care of COVID-19 patients
Devaux, Y., Firat, H., Schneider, R., Petretto, E., deWindt, L. J., Brandenburger, T., Baker, A., Karaduzovic-Hadziabdic, K., Martelli, F., Ferdinandy, P., Scholz, M., Lustrek, M., Badimon, L. & Ferreira, L.
1/11/20 → 1/11/22
Project: Research
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LncSSH1: LONG NONCODING RNAs IN TISSUE REPAIR
FNR - Fonds National de la Recherche
1/08/20 → 31/07/23
Project: Research
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Association between Dietary Factors and Constipation in Adults Living in Luxembourg and Taking Part in the ORISCAV-LUX 2 Survey
Rollet, M., Bohn, T., Vahid, F., ORISCAV Working Group, Pastore, J., Aguayo, G., Le Coroller, G., Vaillant, M., Samouda, H., Appenzeller, B., Malisoux, L., Couffignal, S., Gantenbein, M., Devaux, Y., Bejko, D., Fagherazzi, G., Perquin, M., Ruiz-Castell, M. & Ernens, I., 1 Jan 2022, In: Nutrients. 14, 1, 18 p., 122.Research output: Contribution to journal › Article › peer-review
Open Access -
Challenges of microRNA-based biomarkers in clinical application for cardiovascular diseases
EU-CardioRNA COST Action CA17129, Feb 2022, In: Clinical and Translational Medicine. 12, 2, p. e585Research output: Contribution to journal › Article › peer-review
Open Access -
Consensus guidelines for the validation of qRT-PCR assays in clinical research by the CardioRNA consortium
de Gonzalo-Calvo, D., Marchese, M., Hellemans, J., Betsou, F., Skov Frisk, N. L., Dalgaard, L. T., Lakkisto, P., Foy, C., Scherer, A., Garcia Bermejo, M. L., Devaux, Y. & EU-CardioRNA COST Action CA17129 (https://cardiorna.eu/), 10 Mar 2022, In: Molecular Therapy - Methods and Clinical Development. 24, p. 171-180 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access