Projects per year
Organization profile
Mission/Activities
The Cardiovascular Research Unit aims to better understand the role of RNAs in heart and brain diseases. Our goal is to develop RNA-based biomarkers and therapeutic approaches to personalise health care. Our current focus is on heart failure, cardiac arrest and Parkinson's disease.
Research projects
Our ongoing research projects address two major areas:
- Biomarkers
Using high-throughput transcriptomics tools, the team seeks to develop RNA-based diagnostic and prognostic biomarkers for cardiovascular and brain diseases. Research projects focus on non-coding RNAs: microRNAs, long non-coding RNAs, and circular RNAs.
- Therapeutics
By focusing on the mechanisms that RNAs regulate the development of diseases, the group aims to facilitate drug discovery.
Strategic goals
- Address the main causes of mortality and morbidity in developed countries: heart and braindiseases
- Fulfil unmet medical needs: lack of diagnostic tools and drugs forpersonalisedhealthcare
- Develop networks of international collaborators
- Collaborate with private partners to bring research products to clinical application
- Perform translational research to push forward personalised medicine.
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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LncSSH1: LONG NONCODING RNAs IN TISSUE REPAIR
FNR - Fonds National de la Recherche
1/08/20 → 31/07/23
Project: Research
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(Epi)transcriptomics in cardiovascular and neurological complications of COVID-19
Jusic, A., Stellos, K., Ferreira, L., Baker, A. H. & Devaux, Y., Sep 2022, In: Journal of Molecular and Cellular Cardiology Plus. 1, 100013.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Association between Dietary Factors and Constipation in Adults Living in Luxembourg and Taking Part in the ORISCAV-LUX 2 Survey
Rollet, M., Bohn, T., Vahid, F., ORISCAV Working Group, Pastore, J., Aguayo, G., Le Coroller, G., Vaillant, M., Samouda, H., Appenzeller, B., Malisoux, L., Couffignal, S., Gantenbein, M., Devaux, Y., Bejko, D., Fagherazzi, G., Perquin, M., Ruiz-Castell, M. & Ernens, I., 1 Jan 2022, In: Nutrients. 14, 1, 18 p., 122.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Association of miR-144 levels in the peripheral blood with COVID-19 severity and mortality
Madè, A., Greco, S., Vausort, M., Miliotis, M., Schordan, E., Baksi, S., Zhang, L., Baryshnikova, E., Ranucci, M., Cardani, R., Fagherazzi, G., Ollert, M., Tastsoglou, S., Vatsellas, G., Hatzigeorgiou, A., Firat, H., Devaux, Y. & Martelli, F., 21 Nov 2022, In: Scientific Reports. 12, 1, 20048.Research output: Contribution to journal › Article › Research › peer-review
Open Access